inheritance Flashcards
gene
section of DNA that codes for a specific protein
protein used by the cell for a specific function
genotype
the genetic constitution of an organism
gene pool
all the alleles within an interbreeding population
population
all the individuals of the same species that occupy the same habitat at the same time
phenotype
expression of its genetic constitution and its interaction within the environment
allele
different version of the same gene
dominant , recessive or codominant
multiple alleles
more than 2 alleles for the same gene
produces a hierarchy of dominance
locus
different alleles for the same gene are found at the same position on the homologous chromosome
homozygous
organism has two copies of the same allele
heterozygous
two copies of a gene are different alleles
dominant allele
always expressed in the phenotype
recessive allele
only expressed in the phenotype if the genotype is homozygous
codominant alleles
equally expressed within the phenotype
eg C(r)C(w)
cross 2 heterozygous always 1:2:1 ratio
pedigree charts
dominant characteristic rules
affected offspring must have at least 1 affected parent
unaffected parent only have unaffected offspring
if both parents affected and have an unaffected offspring both parents must be heterozygous
hardy weinburg equations
p + q = 1
p^2 +2pq + q^2 = 1
P = frequency of dominant allele
q = frequency of recessive allele
p^2 = frequency of homozygous dominant
2pq = frequency of heterozygous
q^2 = frequency of homozygous recessive
what does hardy weinburg predict
the allelic frequencies of a particular gene will remain constant over generation
assumes there is no
mutations
migration or emigration
selection for a particular allele
large population
mating is random
monohybrid inheritance
normal
inheritance of a single gene which determines a single characteristic
if you cross 2 heterozygous individuals together always a 3:1 ratio
pedigree charts
recessive characteristic rules
unaffected parents can have an affected offspring if they are heterozygous
sex linked genes
gene found on the x chromosome
a female would need to have two copies of a recessive allele for it to appear in the phenotype whereas male only need one
in who are sex linked genes more common
more common in males
they show a mother to son inheritance pattern and often skip a generation
to prove a characteristic is not sex linked
dads and daughters
-if a daughter is affected
-her father is not
-it is a recessive characteristic
-it is not sex linked
mothers and sons
-if a son is affected
-his mum is not
-it is a dominant characteristic
-it is not sex linked
dihybrid inheritance
when an organism has two genes linked on the same chromosome or on different chromosome
eg AaBb
gametes are
AB Ab aB ab
double heterozygote ratio - 9:3:3:1
autosomal linked
when 2 genes are automally linked they do not follow the expected phenotypic ratio for a dihybrid cross between heterozygous parents
epistatis
interaction between 2 genes where one allele influences the expression of another
ratios add up to 16 but do not show 9:3:3:1