inhalers for COPD Flashcards
group A
bronchodilator
0-1 moderate exacerbations (not leading to hospital admission
mMRC 0-1, CAT<10
Short acting bronchodilators
SABA and SAMA
albuterol
Proventil, porair, Ventolin
SABA
MDIs
rescue relief
albuterol
accuneb
SABA
neb
rescue relief
levalbuterol
xopenex
SABA
MDI and neb
decreases risk of tachycardia
ipratropium
atrovent
SAMA
MDI and neb
albertrol/ipratropium
Combivent Respimat
albuterol/ipratropium
duonebs
neb
long acting bronchodilators
LABA and LAMA
salmeterol
servant diskus
LABA
slowest onset
formoterol
perforomist
LABA
neb
arformterol
brovana
LABA
neb
olodaterol
striverdi Respimat
LABA
tiotropium
Spiriva Respimat
LAMA
longest onset
umeclidinium
incruse ellipta
LAMA
aclidinium
tudorza pressair
LAMA
glycopyrrolate
lonhala magnair
LAMA
neb
glycopyrrolate
seebri neohaler
revefenacin
yupelri
neb
group B
LABA and LAMA
0-1 moderate exacerbations (not leading to hospital admission)
mMRC>2, CAT>10
umeclidinium/vilanterol
anoro ellipta
LABA/LAMA
slowest onset
glycopyrrolate/formoterol
bevespi aeresphere
LABA/LAMA
aclidinium/formoterol
duaklir pressair
LABA/LAMA
tiotropium/olodaterol
stiolto Respimat
group E
LABA and LAMA consider inhaled corticosteroid if eosinophils >300
>2 moderate exacerbations or >1 leading to hospitalization
beclomethasone
qvar redihaler
ICS
budesonide
pulmicort
ICS
DPI and neb
fluticasone
flovent
ICS
fluticasone
arnuity ellipta
ICS
mometasone
asmanex twisthaler
ICS
mometasone
asmanex
ICS
MDI
budesonide/formoterol
Symbicort
ICS/LABA
fluticasone/vilanterol
breo ellipta
ICS/LABA
fluticasone/salmeterol
Advair
ICS/LABA
mometasone/formoterol
bulera
ICS/LABA
budesonide/glycopyrrolate/formoterol
breztri aerosphere
ICS/LAMA/LABA
fluticasone/umeclidinium/vilanterol
trelegy ellipta
ICS/LAMA/LABA
for exacerbations can add these if
roflumilast
daliresp
exacerbations present and inhalers are maxed
FEV1<50% and has chronic bronchitis
DO NOT USE WITH THEOPHYLLINE
dupilumab
dupixent
adherent to triple therapy
chronic bronchitis and history of 2 moderate exacerbations or 1 severe in the past year
eosinophil >300
azithromycin
Zithromax
when exacerbations present and inhalers are maxed
smoking cessation is complete
ensifentrine
ohtuvayre
improves dyspnea and lung function but not exacerbations