Inhalers and others Flashcards

1
Q

Albuterol - brand name and type

A

Proventil HFA, Ventolin HFA, Proair
short acting beta 2 agonist (SABAs)

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2
Q

albuterol - indication

A

acute symptom relief in asthma and COPD, prevention of exercise-induced asthma (RESCUE MED)

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3
Q

albuterol - MOA

A

stimulates beta-2 receptors in the airways, causes bronchial smooth muscle relaxation

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4
Q

albuterol - contraindication

A

hypersensitivity

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5
Q

albuterol - common reaction

A

tremor
nervousness/excitement
tachycardia
pharyngitis
rhinitis
URTI

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6
Q

albuterol - rare but serious reaction

A

bronchospasm
pulmonary edema
atrial fibrillation

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7
Q

albuterol - counsel

A

if metered dose: shake well and prime
follow up with prescriber if frequent use is required

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8
Q

albuterol - alternatives

A

levalbuterol (Xopenex)

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9
Q

tiotropium - brand name and type

A

Spiriva
long acting antimuscarinic antagonist (LAMA)

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10
Q

tiotropium - indication

A

maintenance medication for COPD and asthma

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11
Q

tiotropium - MOA

A

inhibition of M3-receptors at the bronchial smooth muscle, leading to bronchodilation

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12
Q

tiotropium - contraindication

A

hypersensitivity to drug
hypersensitivity to MILK PROTEIN (SPIRIVA HANDIHALER ONLY)

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13
Q

tiotropium - common reaction

A

extension of anticholinergic effects: Xerostomia (dry mouth)
URTI
pharyngitis

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14
Q

tiotropium - rare but serious reaction

A

worsening of bronchospasm, bowel obstruction

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15
Q

tiotropium - counsel

A

dont use for quick relief of symptom
for handihaler: capsule are to be punctured and contents inhaled using the device. DO NOT SWALLOW

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16
Q

fluticasone - brand name and type

A

flovent, arnuity, armonair
inhaled corticosteroids (ICS)

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17
Q

fluticasone - MOA

A

reduction and prevention of airway inflammation

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18
Q

fluticasone - indication

A

asthma (maintenance)

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19
Q

fluticasone - contraindication

A

hypersensitivity of the drug
hypersensitivity to MILK PROTEIN (dry powder inhalers only)
do not use for acute flares of asthma or status asthmaticus

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20
Q

fluticasone - common reaction

A

pharyngeal candidiasis (oral thrush), hoarsness

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20
Q

fluticasone - rare but serious reaction

A

pneumonia
glaucoma, cataracts (less likely with proper administration)
secondary hypocortisolism, osteoporosis (less likely due to minimal systemic absorption)

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21
Q

fluticasone - counsel

A

not for quick relief of symptoms
rinse mouth after use -> reduce risk of oral thrush

22
Q

fluticasone - alternatives

A

Budesonide (Pulmicort)

23
Q

Fluticasone/Salmeterol - brand name and type

A

Advair, AirDuo, Wilexa, other
inhaled corticosteroids/Long acting Beta-2 agnoist (ICS/LABA)

24
Fluticasone/Salmeterol - MOA
ICS: anti-inflammatory LABA: bronchodilation
25
Fluticasone/Salmeterol - Indication
asthma and COPD (maintenance)
26
Fluticasone/Salmeterol - contraindication
hypersensitivity of the drug hypersensitivity to MILK PROTEIN (dry powder inhalers ONLY) do not use for acute flares of asthma or staus asthmaticus posaconazole co-administration -> lead to an increase steroid concentration and systemic ADRs
27
Fluticasone/Salmeterol - common reaction
headache pharyngitis pharyngeal candidiasis (oral thrush) hoarseness URTI
28
Fluticasone/Salmeterol - rare but serious reaction
atrial fibrillation myocardial infarction (MI) osteoporosis bronchospasm
29
Fluticasone/Salmeterol - counsel
not for quick relief symptoms (except symbicort) rinse mouth after use -> reduce risk of oral thrush
30
Fluticasone/Salmeterol - alternatives
Budesonide/formoterol (Symbicort)
31
Ipratropium/Albuterol - brand name and type
combivent short-acting muscarinic antagonist/short-acting beta-2 agonist (SAMA/SABA)
32
Ipratropium/Albuterol - indication
COPD (quick relief)
33
Ipratropium/Albuterol - MOA
see SAMA and SABA mechanisms
34
Ipratropium/Albuterol - contraindication
hypersensitivity to drug hypersensitivity to atropine or its derivatives soy/peanut allergy -> a CI for the OLD version of these inhalers
35
Ipratropium/Albuterol - common reaction
bronchitis URTI headache nervousness tremor insomnia
36
Ipratropium/Albuterol - rare but serious reaction
pneumonia angle closure glaucoma worsening bronchospasms
37
Ipratropium/Albuterol - counsel
quick relief of symptoms
38
montelukast - brand name and type
singulair leukotriene receptor antagonist
39
montelukast - indication
asthma (maintenance) exercise induced bronchospasm allergic rhinitis
40
montelukast - MOA
blind leukotriene receptors to inhibit their effect, results in bronchodilation
41
montelukast - contraindications
hypersensitivity to drug
42
montelukast - BLACK BOX WARNINGS
behavior and mood effects (suicide [thoughts])
43
montelukast - common reaction
dizziness headache fatigue (generally well-tolerated)
44
montelukast - rare but serious reaction
aggressive or altered behavior suicidal thoughts cholestatic hepatitis allergic granulomatous angitis
45
montelukast - counsel
not for quick symptom relief usually taken at night/bedtime
46
Epinephrine - brand name and type
EpiPen Autoinjector Anaphylaxis Agent
47
Epinephrine - indication
emergency treatment of acute anaphylaxis due to allergic reaction
48
Epinephrine - MOA
Alpha and beta agonist
49
Epinephrine - contraindications
none in emergency situations
50
Epinephrine - common reaction
anxiety apprehension headache nausea palpitations pale complexion restlessness sweating tremor
51
Epinephrine - rare but serious reaction
angina cardia dysthrhythmia pulmonary edema ventricular fibrilation
52
Epinephrine - counsel
proper administration technique immediately seek care after administration, even if feeling better after use