Inhalers and others Flashcards

1
Q

Albuterol - brand name and type

A

Proventil HFA, Ventolin HFA, Proair
short acting beta 2 agonist (SABAs)

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2
Q

albuterol - indication

A

acute symptom relief in asthma and COPD, prevention of exercise-induced asthma (RESCUE MED)

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3
Q

albuterol - MOA

A

stimulates beta-2 receptors in the airways, causes bronchial smooth muscle relaxation

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4
Q

albuterol - contraindication

A

hypersensitivity

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5
Q

albuterol - common reaction

A

tremor
nervousness/excitement
tachycardia
pharyngitis
rhinitis
URTI

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6
Q

albuterol - rare but serious reaction

A

bronchospasm
pulmonary edema
atrial fibrillation

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7
Q

albuterol - counsel

A

if metered dose: shake well and prime
follow up with prescriber if frequent use is required

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8
Q

albuterol - alternatives

A

levalbuterol (Xopenex)

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9
Q

tiotropium - brand name and type

A

Spiriva
long acting antimuscarinic antagonist (LAMA)

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10
Q

tiotropium - indication

A

maintenance medication for COPD and asthma

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11
Q

tiotropium - MOA

A

inhibition of M3-receptors at the bronchial smooth muscle, leading to bronchodilation

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12
Q

tiotropium - contraindication

A

hypersensitivity to drug
hypersensitivity to MILK PROTEIN (SPIRIVA HANDIHALER ONLY)

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13
Q

tiotropium - common reaction

A

extension of anticholinergic effects: Xerostomia (dry mouth)
URTI
pharyngitis

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14
Q

tiotropium - rare but serious reaction

A

worsening of bronchospasm, bowel obstruction

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15
Q

tiotropium - counsel

A

dont use for quick relief of symptom
for handihaler: capsule are to be punctured and contents inhaled using the device. DO NOT SWALLOW

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16
Q

fluticasone - brand name and type

A

flovent, arnuity, armonair
inhaled corticosteroids (ICS)

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17
Q

fluticasone - MOA

A

reduction and prevention of airway inflammation

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18
Q

fluticasone - indication

A

asthma (maintenance)

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19
Q

fluticasone - contraindication

A

hypersensitivity of the drug
hypersensitivity to MILK PROTEIN (dry powder inhalers only)
do not use for acute flares of asthma or status asthmaticus

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20
Q

fluticasone - common reaction

A

pharyngeal candidiasis (oral thrush), hoarsness

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20
Q

fluticasone - rare but serious reaction

A

pneumonia
glaucoma, cataracts (less likely with proper administration)
secondary hypocortisolism, osteoporosis (less likely due to minimal systemic absorption)

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21
Q

fluticasone - counsel

A

not for quick relief of symptoms
rinse mouth after use -> reduce risk of oral thrush

22
Q

fluticasone - alternatives

A

Budesonide (Pulmicort)

23
Q

Fluticasone/Salmeterol - brand name and type

A

Advair, AirDuo, Wilexa, other
inhaled corticosteroids/Long acting Beta-2 agnoist (ICS/LABA)

24
Q

Fluticasone/Salmeterol - MOA

A

ICS: anti-inflammatory
LABA: bronchodilation

25
Q

Fluticasone/Salmeterol - Indication

A

asthma and COPD (maintenance)

26
Q

Fluticasone/Salmeterol - contraindication

A

hypersensitivity of the drug
hypersensitivity to MILK PROTEIN (dry powder inhalers ONLY)
do not use for acute flares of asthma or staus asthmaticus
posaconazole co-administration -> lead to an increase steroid concentration and systemic ADRs

27
Q

Fluticasone/Salmeterol - common reaction

A

headache
pharyngitis
pharyngeal candidiasis (oral thrush)
hoarseness
URTI

28
Q

Fluticasone/Salmeterol - rare but serious reaction

A

atrial fibrillation
myocardial infarction (MI)
osteoporosis
bronchospasm

29
Q

Fluticasone/Salmeterol - counsel

A

not for quick relief symptoms (except symbicort)
rinse mouth after use -> reduce risk of oral thrush

30
Q

Fluticasone/Salmeterol - alternatives

A

Budesonide/formoterol (Symbicort)

31
Q

Ipratropium/Albuterol - brand name and type

A

combivent
short-acting muscarinic antagonist/short-acting beta-2 agonist (SAMA/SABA)

32
Q

Ipratropium/Albuterol - indication

A

COPD (quick relief)

33
Q

Ipratropium/Albuterol - MOA

A

see SAMA and SABA mechanisms

34
Q

Ipratropium/Albuterol - contraindication

A

hypersensitivity to drug
hypersensitivity to atropine or its derivatives
soy/peanut allergy -> a CI for the OLD version of these inhalers

35
Q

Ipratropium/Albuterol - common reaction

A

bronchitis
URTI
headache
nervousness
tremor
insomnia

36
Q

Ipratropium/Albuterol - rare but serious reaction

A

pneumonia
angle closure glaucoma
worsening bronchospasms

37
Q

Ipratropium/Albuterol - counsel

A

quick relief of symptoms

38
Q

montelukast - brand name and type

A

singulair
leukotriene receptor antagonist

39
Q

montelukast - indication

A

asthma (maintenance)
exercise induced bronchospasm
allergic rhinitis

40
Q

montelukast - MOA

A

blind leukotriene receptors to inhibit their effect, results in bronchodilation

41
Q

montelukast - contraindications

A

hypersensitivity to drug

42
Q

montelukast - BLACK BOX WARNINGS

A

behavior and mood effects (suicide [thoughts])

43
Q

montelukast - common reaction

A

dizziness
headache
fatigue (generally well-tolerated)

44
Q

montelukast - rare but serious reaction

A

aggressive or altered behavior
suicidal thoughts
cholestatic hepatitis
allergic granulomatous angitis

45
Q

montelukast - counsel

A

not for quick symptom relief
usually taken at night/bedtime

46
Q

Epinephrine - brand name and type

A

EpiPen Autoinjector
Anaphylaxis Agent

47
Q

Epinephrine - indication

A

emergency treatment of acute anaphylaxis due to allergic reaction

48
Q

Epinephrine - MOA

A

Alpha and beta agonist

49
Q

Epinephrine - contraindications

A

none in emergency situations

50
Q

Epinephrine - common reaction

A

anxiety
apprehension
headache
nausea
palpitations
pale complexion
restlessness
sweating tremor

51
Q

Epinephrine - rare but serious reaction

A

angina
cardia dysthrhythmia
pulmonary edema
ventricular fibrilation

52
Q

Epinephrine - counsel

A

proper administration technique
immediately seek care after administration, even if feeling better after use