Inhaled Anesthesia

Question 1

Inhaled Anesthesia in general

Answer 1

CNS: depression, increase CBF, no analgesia, decrease MAP,
CVS: decrease BP, decrease arrhythmias
RS: depress ventilation
risk in sick patients and to surgeons
O:G (oil gas ratio if high then enters brain rapidly- potency)
B:G (blood gas solubility, low you have a fast wake up)
SVP (saturated vapor pressure- how easy it is vaporizing)

Question 2

Isoflurane

Answer 2

SVP : 240
B:G 1.46 
O:G 97 
MAC 1.3%
Halogenated ether
Cause: decrease TPR --> decrease BP, hypoventilation, airway irritation

Question 3

Sevoflurane

Answer 3

SVP: 157
B:G 0.65
O:G 53
MAC 2.4%
decrease TPR - Decrease BP
less depression than iso

Question 4

Desflurane

Answer 4

SVP: 243
B:G 2.3
O:G 220
MAC 0.8%
halogenated hydrocarbon
decrease BP
sensitizes myocardium 
dose dependent respiratory depression
very expensive

Question 5

Halothane

Answer 5

SVP 243
B:G 2.3
O:G 220
MAC 0.8%
decrease BP, sensitizes myocardium- arrhythmias
resp depression
HEPATOTOXIC
off market

Question 6

Nitrous Oxide

Answer 6

onset rapid
not potent 
MAC 200%
no metab
provides analgesia
mils SNS stim
non irritant, augments ventilation
Hypoxia risk, arrhythmias, death