Inhalation Induction Flashcards
Fi
inspired concentration of volatile agent
Fa
concentration of volatile agent in alveoli (and expiratory tubing)
inhalation induction mechanism
- volatile agent on
- Fi increases
- Fa increases
- agent diffuses into blood
- agent diffuses from blood to brain
- pt asleep when conc in brain is sufficient
how does concentration gradient effect diffusion speed?
the greater the conc gradient from the lungs to blood the faster the diffusion to the blood
T/F diffusion is slow at first and then rapid.
false, rapid at first then slows as the concentration gradients decrease
Fa/Fi ratio
how concentrated the alveoli are compared to machine
why is the Fa/Fi ratio less than one?
b/c blood is always absorbing agent from the lungs
list the volatile agents in order from fastest to slowest for Fa/Fi ration approaching 1
nitrous oxide des sevo iso halo
what does a steep slope on the Fa/Fi curve mean?
Fa is rapidly increasing and leads to faster diffusion and faster induction
why is low blood solubility important?
slower initial diffusion into blood and Fa builts up, rapidly diffuses to brain b/c low blood solubility
high blood solubility
quickly diffuses to blood, slow to the brain bc wants to stay in the blood
If Desflurane has a lower blood gas coefficient than nitrous oxide, why does nitrous oxide have a steeper Fa/Fi curve?
Because N2O is typically used in much higher concentrations
how to speed up inhalational induction
higher % poison
higher FGF rate
decrease circuit volume
agent with lowest blood solubility
how much oxygen does a patient need?
250mL
When do you need to run at least 2L/min?
sevo is used