Infliximab Flashcards

1
Q

Mecanismo de acción

A

Es un anticuerpo monoclonal (IgG1 kappa quimérico) que inhibe a TNF-alfa.

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2
Q

Indicaciones terapéuticas

A

Tratamiento de artritis reumatoide y otras enfermedades autoinmunes

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3
Q

Reacciones adversas

A

Mayor riesgo de infecciones, lupus inducido por fármacos, urticaria, reacciones de hipersensibilidad

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4
Q

Farmacocinética

A

I.V
D: 5670.8 mL
E: 11,72 ml/h

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5
Q

Embarazo y lactancia

A

No se puede descartar el riesgo fetal.

No se puede descartar el riesgo de lactantes.

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6
Q

Contraindicaciones

A

Insuficiencia cardíaca, de moderada a grave, hipersensibilidad.

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