Inflammatory Mediators Flashcards
1
Q
what causes vasodilation?
A
Histamine, prostaglandin, PAF, NO
2
Q
What causes vasoconstriction?
A
Serotonin, Thromboxane
3
Q
What causes increased permeability?
A
Histamine, serotonin, bradykinin and clotting factors, C3a and C5a, Leukotrienes (LTC-E4), PAF, O2-, neuropeptides (substance P)
4
Q
what causes chemotaxis?
A
C5a, luekotrienes (LTB4), IL-8, chemokines, PAF
5
Q
What causes pain?
A
Prostaglandin, Bradykinin, Substance P
6
Q
what causes fever
A
IL-1, IL-6, TNF, prostaglandin
7
Q
what cause endothelial activation?
A
TNF, IL-1, NO, C5a, C4a, C3a, Anatgonized by lipoxin
8
Q
what causes tissue damage?
A
Lysosomal enzymes, O2, NO
9
Q
Antiinflammatory mediators?
A
IL-10, TGF beta, Lipoxins
10
Q
Plasma Derived Mediators
A
Compliment, Coagulation, Kinin
