Inflammatory Bowel Disease Flashcards
Appendicitis
- inflammation of the appendix
- Caused by obstruction of the lumen or opening of the appendix
- Fecaliths (hard pieces of stool) can be initial cause of obstruction
- Adolescents or young adults at inc risk
Peritonitis
- inflammation of peritoneum
- Results from infection of peritoneum due to puncture (surgery or trauma), septicemia, or rupture of part of GI tract
- Can lead to septicemia
- Life threatening event
Gastroenteritis
- inflammation of stomach and small intestine
- Triggered by infection: either bacterial or viral
- Vomiting and frequent, watery stools–>place the client at inc risk of fluid and electrolyte imbalance and impaired nutrition
what characterizes UC and Crohn’s?
- Frequent stools
- Crampy abdominal pain
- Exacerbations
- Remissions
ulcerative colitis (UC)
- edema and inflammation primarily in the rectum and rectosigmoid colon
- In severe cases, it can involve the entire length of the colon
- Mucosa and submucosa become hyperemic (inc in blood flow)
- Colon will become edematous and reddened
- Can lead to abscess formation
- Edema and thickened bowel mucosa can cause partial bowel obstruction
- Intestinal mucosal cell changes can lead to colon cancer or insufficient absorption of vitamin B12
- Classified as either mild, moderate, severe, and fulminant
Crohn’s Dz
- inflammation and ulceration of the GI tract
- Often at distal ileum
- All bowel layers can be involved and lesions are sporadic
- Fistulas are common
- Can involve the entire GI tract from the mouth to the anus
- Malabsorption and malnutrition: develop when the jejunum and ileum become involved
- Requires supplemental vitamins and minerals
- Possibly includes vitamin B12 injections
- Requires supplemental vitamins and minerals
diverticulitis
- inflammation and infection of the bowel mucosa caused by bacteria, food, or fecal matter trapped in one or more diverticula (pouch like herniations in the intestinal wall)
- Not the same as diverticulosis: presence of many small diverticula in colon W/O inflammation
- Not all clients with diverticulosis develop diverticulitis
- Diverticula can perforate and cause peritonitis, and or severe bleeding
UC: risk factors
- genetics
- caucasians
- Jewish heritage
- gender and age:
- adolescence to young adulthood–>More often in females
- Older adulthood–>more often in males
Crohn’s dz: risk factors
- genetics
- Jewish heritage
- develops in adolescents and young adults, but can occur at any age
- tobacco use
Diverticulitis: risk factors
- African Americans
- occurs more often in older adults and more frequently in men
UC: expected findings
- Abdominal pain/cramping: often left lower quadrant pain
- Anorexia and weight loss
- Fever
- Diarrhea: up to 15-20 liquid stools/day
- Stools can contain mucus, blood, or pus
- Abdominal distention, tenderness, and/or firmness on palpation
- High pitched bowel sounds
- Rectal bleeding
Crohn’s dz: expected findings
- Abdominal pain/cramping: often right lower quadrant pain
- Anorexia and weight loss
- Fever
- Diarrhea: 5 loose stools/day w/ mucus or pus
- Abdominal distention, tenderness, and/or firmness upon palpation
- High pitched bowel sounds
- Steatorrhea
Diverticulitis: expected findings
- Acute onset of abdominal pain in left lower quadrant
- n/v
- Fever
- Chills
- Tachycardia
UC: lab tests
- H&H: dec
- ESR: inc
- WBC: inc
- CRP: inc
- Serum albumin: dec
- Stool for occult blood: can be positive
- K+, Mg, Ca: dec
Crohn’s dz: lab tests
- H&H: dec
- ESR: inc
- WBC: inc
- CRP: inc
- Serum albumin: dec
- Folic acid & B12: dec
- Anti glycan antibodies: inc
- Stool for occult blood: can be positive
- Urinalysis: WBC
- K+, Mg, Ca: dec
diverticulitis: lab tests
- H&H: dec
- ESR: inc
- WBC: inc
- Stool for occult blood: can be positive
chronic inflammatory bowel dz: diagnostic procedure
- Magnetic resonance enterography: can be used w/ all IBD
- Client edu:
- remain NPO for 4-6 hr prior
- Will have to drink contrast medium
- Client edu:
UC: diagnostic procedures
- sigmoidoscopy/colonoscopy: can diagnose UC
- Barium enema: can help distinguish UC from other dz processes
- CT scan or MRI: can identify presence of abscesses
- Stool exam: for the presence of parasites or microbes
Crohn’s dz: diagnostic procedures
- Endoscopy:
- Can use pill cam
- Proctosigmoidoscopy: performed to identify inflamed tissue
- colonoscopy/sigmoidoscopy: can visualize large intestine and rectum
- Abdominal U/S, x-ray, CT scan:
- CT scan shows bowel thickening
- Barium enema
Crohn’s dz: barium enema
- barium inserted into rectum as contrast media for x-ray
- Allows for visualization of rectum and large intestine
- Used to diagnose UC
- Can also show presence of diverticulosis but is contraindicated in diverticulitis due to risk of perforation
- Nursing Actions:
- Monitor postprocedure for manifestations of bowel perforation: rectal bleeding, firm abdomen, tachycardia, hypoTN
- Findings:
- Small intestine ulcerations and narrowing consistent with Crohn’s
- Ulcerations and inflammation of sigmoid colon and rectum significant for UC
- Client Edu:
- NPO and bowel prep
- May have possible abdominal discomfort and cramping during barium enema
UC & Crohn’s dz: nursing care
- Seek care for bowel obstruction or perforation: fever, severe abdominal pain, vomiting
- Instruct on med therapy and vitamin supplements
- Monitor by colonoscopy for inc risk of colon cancer
- If long exacerbations, NPO status and administer TPN to promote bowel rest
- Eat high protein, high calorie, low fiber foods
- Identify trigger foods
- Avoid caffeine and alcohol
- Take a multivitamin with iron
- Small frequent meals
- Monitor for electrolyte imbalance, esp K, b/c of diarrhea
- Monitor I&O–>assess for dehydration
- Educate regarding use of B12 injections
diverticulitis: nursing care
- If severe manifestations (pain, high fever), client is hospitalized, NPO, and receives NG suctioning, IV fluids, IV abx, and opioids for pain
- Mild diverticulitis: home care–>abx, analgesics, antispasmodics, rest
- Clear liquid diet until manifestations subside, then progress to low fiber diet
- Add fiber to diet once solid foods are tolerated w/o problems
- Advance slowly to high fiber diet
- Avoid seeds or indigestible material which can block diverticulum (nuts, popcorn, seeds)
- Avoid foods or drinks that irritate the bowel: alcohol, limit fat
- Bulk forming laxatives, fluids, avoid enemas
chronic inflammatory bowel dz: med classes
- 5 amino salicylic acid (anti-inflammatory): sulfonamides, non-sulfonamides
- corticosteroids
- immunosuppressants
- immunomodulators
- antidiarrheals
chronic inflamm bowel dz: 5 aminosalicylic acid: anti-inflammatory
Reduces inflammation of intestinal mucosa and inhibits PGs
chronic inflamm bowel dz: sulfonamides
- Nursing considerations:
- Contraindicated in sulfa allergy
- Monitor CBC, kidney and hepatic fcn
- Given orally
- ADRs: nausea, fever, rash, agranulocytosis, hemolytic anemia, macrocytic anemia
- 2-4 for therapeutic effects
- Client Edu:
- Take w/ full glass of water after meals
- Avoid sun exposure
- Inc fluids to 2 L/day
- Can cause urine, skin, contact lenses to have yellow orange color
- Report if n/v, anorexia, sore throat, rash, bruising, fever occur
- Maintenance dose: 2-4 g/day
chronic inflamm bowel dz: nonsulfonamides
- mesalamine, balsalazide, olsalazine
- Nursing considerations:
- ADRs not as serious as sulfonamides
- Contraindicated if salicylate or sulfa allergy
- Monitor for kidney toxicity
- Report HA or GI discomfort or diarrhea
chronic inflamm bowel dz: corticosteroids
- Reduces inflammation and pain
- Nursing considerations:
- If rectal inflammation: topical steroids administered by retention enema
- Used to induce remission
- Don’t use long term
- Can cause adrenal suppression, osteoporosis, infection, cushingoid syndrome
- Use low doses
- Monitor BP, electrolyte, glucose
- Can slow healing
- Client Edu:
- Take w/ food
- Don’t d/c suddenly
- Report unexpected inc in weight
- Avoid crowds
- Report evidence of infection
chronic inflamm bowel dz: immunosuppressants
- cyclosporine, methotrexate, azathioprine, mercaptopurine
- Nursing Considerations:
- Monitor for pancreatitis and neutropenia
- 6 mos to see therapeutic effects
- Not used as monotherapy
- Reserved for refractory dz due to toxicity
- Client Edu:
- Avoid crowds
- Report evidence of infection
- Monitor for bleeding, bruising, infection
chronic inflamm bowel dz: immunomodulators
- infliximab, adalimumab, natalizumab, certolizumab
- Suppress immune response and inhibits TNF
- Nursing Considerations:
- Follow directions for IV use
- ADRs: chills, fevers, HTN/hypoTN, dysrhythmias, blood dyscrasias
- Monitor liver enzymes, coagulation studies, CBC
- Client Edu:
- Avoid crowds and report evidence of infection
- Report bleeding, bruising, infection
chronic inflamm bowel dz: antidiarrheals
- diphenoxylate and atropine, loperamide
- Suppress number of stools
- Nursing Considerations:
- Dec risk of fluid vol deficit and electrolyte imbalance
- Reduce discomfort
- Can lead to toxic megacolon: massive dilation of colon with risk of development of gangrene and peritonitis
- Observe for: hypoTN, fever, abdominal distention, dec/absence of bowel sounds
- Watch for respiratory depression
- Client Edu:
- Avoid hazardous activities
diverticulitis: antimicrobials
- cipro, metronidazole, SMX
- Treat infection (dec inflammation in Crohn’s)
- Nursing considerations:
- Can cause superinfection
- Watch for thrush or yeast infection
- d/c cipro for tendon pain b/c can lead to tendon rupture
- Dec dose used if client has impaired kidney
- Monitor kidney and hepatic studies
- Client edu:
- Use may darken and is harmless
- Monitor for manifestations of CNS effects: numbness of extremities, ataxia, seizures
UC: therapeutic procedures
colectomy w/ or w/o ileostomy
Crohn’s dz: therapeutic procedures
- Laparoscopic stricturoplasty to inc diameter of bowel for bowel strictures
- Surgical repair of fistulas or in response to other complications related to dz (perforation)
diverticulitis: therapeutic procedures
- (dependent on problem)
- Required for rupture that results in peritonitis, bowel obstruction, uncontrolled bleeding, abscess
- Colon resection w/ or w/o colostomy
chronic inflamm bowel dz: therapeutic procedures pre/post op
- Pre Op:
- Creation of stoma planned–>collaborate w/ enterostomal therapy
- Administer abx bowel prep
- Administer cleansing enema or laxative
- Post Op:
- Remain NPO and have NG tube to suction
- An ileostomy can drain as much as 1000 mL/day
- Prevent fluid vol deficit
- Replace fluid loss with IV fluids if client is NPO
- Oral hydration is slowly introduced in 1-2 days
chronic inflamm bowel dz: complications
- peritonitis
- bleeding due to deterioration of the bowel
- F&E imbalance
- abscess and fistula
- toxic megacolon
peritonitis:: what is it? assessment?
- Life threatening inflammation of peritoneum and lining of abdominal cavity
- Often caused by bacteria in peritoneal cavity
- Assessment:
- Rigid, board like abdomen
- Abdominal distention
- n/v
- Rebound tenderness
- Tachycardia
- Fever
peritonitis: nursing actions
- Client in Fowler’s or semi Fowler’s to promote drainage of peritoneal fluid and improve lung expansion
- Monitor respiratory status: turn, cough, deep breathe, O2
- Monitor NG suction
- Keep NPO
- Monitor F&E and monitor for hypovolemia
- Administer IV abx
- If surgery performed:
- Closely monitor V/S post op
- Monitor I&O every hour
- Monitor surgical dressing for bleeding
- If wound irrigation post op: use sterile technique
peritonitis: client edu
- Maintain adequate rest and resume home activity slowly
- No heavy lifting for 6 weeks
- Monitor for infection
chronic inflamm bowel dz: bleeding due to deterioration of bowel as a complication
- Bleeding due to deterioration of bowel
- Nursing actions:
- Watch for rectal bleeding
- Monitor V/S
- Check labs: H&H, coag factors
- Client Edu:
- Report rectal bleed
- Explain importance of bed rest
chronic inflamm bowel dz: F&E imbalance as a complication
- occurs due to loss of fluid thru diarrhea, vomiting, NG suctioning
- Nursing actions:
- Monitor lab values, provide replacement therapy
- Monitor weight
- Assess for fluid vol deficit
- Client edu:
- Record number of loose stools
- Maintain fluid intake
- Follow prescribed diet
chronic inflamm bowel dz: abscess and fistula as a complication
- occurs due to destruction of bowel wall, leading to infection
- Nursing actions:
- Monitor F&E
- Watch for dehydration
- High protein and calorie (at least 3000) diet with low fiber
- Vitamin supplement
- Talk to enterostomal therapist to prevent skin breakdown and promote wound healing
- Monitor for infection
chronic inflamm bowel dz: toxic megacolon
- occurs due to inactivity of colon
- Massive dilation of colon occurs and client at risk for perforation
- Nursing actions:
- Maintain NG suction
- Administer IV F&E
- Administer meds: abx, corticosteroids
- Prep for surgery (usually an ileostomy) if client does not begin to show improvement w/in 72 hours