Inflammatory arthritis Flashcards
Name examples of inflammatory arthritis
Rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis
What is rheumatoid arthritis?
Inflammatory autoimmune disorder causing a symmetrical polyarthritis
what are the signs and symptoms of RA?
Symmetrical swollen, painful, stiff joints. Worse in the morning (lasts longer than 30 mins)
MCP, PIP, MTP affected. DIPs spared
ulnar deviation, swan neck, boutonniere deformity
extra-articular: pleural effusions, pericarditis, scleritis, amyloidosis
investigations of RA?
XRAY (peri-articular erosions, joint space narrowing)
Bloods (+ve rheumatoid factor (Sensitive), +ve anti-ccp (specific)
Management of RA?
DMARDs eg. methotextrate
biological therapist eg. TNF-alpha blockers Infliximab