Inflammation/Tissue Repair Flashcards

1
Q

Name the 4 parts to the inflammatory response:

A
  1. Vascular
  2. Hemostatic
  3. Cellular
  4. Immune
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2
Q

During the first 0-2 minutes after injury the body’s vascular response starts vaso____, in which time MARGINATION occurs

A

Constriction

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3
Q

Name the 3 vasodilators that are released by platelets and mast cells during the vascular inflammatory response

A
  1. Histamine
  2. Bradykinin
  3. Prostaglandin
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4
Q

During the hemostatic response, ruptured vessels retract and platelets aggregate and deposit ___, trapping RBCs and forming a clot.

A

Fibrin

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5
Q

A mass of clotted blood in an organ or tissue is called?

A

Hematoma

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6
Q

During the cellular response to inflammation, leukocytes migrate to the area of damage (most are neutrophils). They rid the area of bacteria and debris by a process called _____

A

Phagocytosis

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7
Q

Cardinal signs of inflammation? (SHARP)

A
Swelling
Heat
Altered (loss) function
Redness
Pain
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8
Q

____ is characterized by early proliferation of new blood vessels and the formation of connective tissue

A

Tissue repair

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9
Q

Tissues that are too damaged to regenerate or cannot regenerate heal with ____ formation

A

Scar

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10
Q

The two phases of tissue repair?

A
  1. Proliferative phase

2. Remodeling phase

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11
Q

The proliferative phase of tissue repair occurs from about day __-__

A

3-20

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12
Q

The remodeling phase of tissue repair begins at about day ___ (there is overlap w/proliferative phase)

A

9

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13
Q

The best scar is only __% as strong as the original tissue.

A

70%

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14
Q

Chronic inflammation results in the replacement of normal tissue with scar tissue. In the musculoskeletal system, this leads to _____, which is promoted by lack of movement through the normal ranges of motion.

A

Adhesions

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