Inflammation/Tissue Repair Flashcards
Name the 4 parts to the inflammatory response:
- Vascular
- Hemostatic
- Cellular
- Immune
During the first 0-2 minutes after injury the body’s vascular response starts vaso____, in which time MARGINATION occurs
Constriction
Name the 3 vasodilators that are released by platelets and mast cells during the vascular inflammatory response
- Histamine
- Bradykinin
- Prostaglandin
During the hemostatic response, ruptured vessels retract and platelets aggregate and deposit ___, trapping RBCs and forming a clot.
Fibrin
A mass of clotted blood in an organ or tissue is called?
Hematoma
During the cellular response to inflammation, leukocytes migrate to the area of damage (most are neutrophils). They rid the area of bacteria and debris by a process called _____
Phagocytosis
Cardinal signs of inflammation? (SHARP)
Swelling Heat Altered (loss) function Redness Pain
____ is characterized by early proliferation of new blood vessels and the formation of connective tissue
Tissue repair
Tissues that are too damaged to regenerate or cannot regenerate heal with ____ formation
Scar
The two phases of tissue repair?
- Proliferative phase
2. Remodeling phase
The proliferative phase of tissue repair occurs from about day __-__
3-20
The remodeling phase of tissue repair begins at about day ___ (there is overlap w/proliferative phase)
9
The best scar is only __% as strong as the original tissue.
70%
Chronic inflammation results in the replacement of normal tissue with scar tissue. In the musculoskeletal system, this leads to _____, which is promoted by lack of movement through the normal ranges of motion.
Adhesions