Inflammation I Flashcards
What are the main causes of acute inflammation?
Infection
Trauma
Foreign bodies
Immune reaction
Necrosis of any kind
The main cell of acute inflammation is?
The Neutrophil (polymorph)
What are the 4 main responses to injury?
Vascular changes
Cellular changes
Chemical mediators
Morphologic patterns
What are the vascular changes in acute infammation?
Changes in flow and vessel caliber
Vasodilation
First invloves arterioles then capillary beds
Mediated by histamine and Nitric oxide
Results in increased heat (calor) and increased redness/eyrthema (rubor)
What, released from inflammatory cells, increase Selectin expression?
Histmamine
Thrombin
….More attractive
After inflammation, the endothelium becomes?
More attractive