Inflammation and fever

Question 1

Vascular acute inflammation

Answer 1

• vasoconstriction
• vasodilation
• increased permeability

Question 2

Cellular acute inflammation

Answer 2

• chemotaxis
• margination
• phagocytosis

Question 3

Cardinal signs

Answer 3

1. Erythema
2. Swelling
3. Warmth
4. Pain

Question 4

Examples of systemic manifestations

Answer 4

• headache
• fatigue
• malaise
• fever

Question 5

Benefits of fever

Answer 5

• enhances phagocytosis and immune response

* inhibits proliferation of microbes

Question 6

Types of exudate

Answer 6

1. Serous
2. Purulent
3. Hemorrhagic
4. Fibrinous
5. Membranous

Question 7

Histamine function

Answer 7

• increased capillary permeability

* capillary dilation

Question 8

Prostaglandin function

Answer 8

• mediates pain
• increased capillary permeability
• capillary dilation

Question 9

Pathogenesis of fever

Answer 9

Bacteria enter body-> produce exogenous pyrogens -> stimulate production of endogenous pyrogens (by defence cells) -> stimulates production of prostaglandin2 (mediated by IL, IL6 and TNF) -> travels to hypothalamic receptor -> adjusts temperature set point (with cAMP)

Question 10

Acute

Answer 10

• vascular

* cellular