Inflammation 2

Question 1

The main type of leukocyte in early inflammatory reactions is

Answer 1

Neutrophils

Question 2

The main type of leukocyte in late inflammatory reactions is

Answer 2

Macrophages

Question 3

The main type of leukocyte in viral infections is

Answer 3

T lymphocytes

Question 4

The main type of leukocyte in hypersensitivity is

Answer 4

Eosinophils

Question 5

List the steps of leukocyte recruitment

Answer 5

Margination
Transmigration
Chemotaxis

Question 6

Differentiate between rolling & adhesion

Answer 6

Rolling is loose attachment of leukocytes to the endothelium

Adhesion is firm attachment of leukocytes to the endothelium

Question 7

Define chemotaxis

Answer 7

Movement of leukocytes toward the irritant under the effect of chemotactic factors that are present at the inflamed area

Question 8

What’s the role of leukocytes at site of inflammation

Answer 8

They ingest causative agents by phagocytosis
They kill bacteria & microbes
They eliminate necrotic tissues & cells
They release chemical mediators

Question 9

Explain engulfment

Answer 9

Phagocytic cells send out pseudopods that surrounds the microbe and internalize it within a phagosome then the phagosome fuses with lysosomes to form phagolysosomes and finally releases its contents

Question 10

The final step in phagocytosis is

Answer 10

Killing & degradation