Inflammation Flashcards
inflammation suggests
a harmful reaction, it is actually a protective response that
is essential for survival. true or false
True
_________ of the noxious agent that is the initiating stimulus for inflammation.
Recognition
What are recruited during inflammation?
Leukocytes and plasma proteins
Removal of the stimulus for inflammation is accomplished
mainly by host cell. True or false
False
Cellular infiltrate of Acute inflammation
Mainly neutrophils
Cellular infiltrate of Chronic Inflammation
Monocytes/macrophages
and lymphocytes
The fifth clinical sign of inflammation was coined by
Rudolf Virchow 19th century
Discovered Phagocytosis by observing the
ingestion of rose thorns by amebocytes of starfish larvae
and of bacteria by mammalian leukocytes
Russian biologist Elie Metchnikoff
TRY TO MEMORIZE CAUSES OF INFLAMMATION
Infections (bacterial, viral, fungal, parasitic) and microbial
toxins
Tissue necrosis
Foreign bodies (splinters, dirt, sutures
Immune reactions (also called hypersensitivity)
Best defined cellular receptor for microbes
Toll-like receptors
All cells have cytosolic receptors. True or false
True
Receptors activate what cytosolic complex?
Inflammasome
The complement system reacts against
microbes and produces products of inflammation. T or F
False. Produce mediators
Give the five R’s of inflammatory response
(1) recognition of the injurious agent, (2) recruitment of leukocytes, (3) removal of the agent, (4) regulation
(control) of the response, and (5) repair (resolution)
Systemic effects of inflammation include
Fever and leukocytes