Inflammation Flashcards
Aspirin
TC: anti inflammatory, anti platelet, NSAID, antipyretic
PC: salicylate
Need to know: cannot give to children under 12 years
Old, such as Tylenol because your liver can die
Identify cels that re predominantly involved in the innate immune response
Eosinophils, mat cells, leukocytes, neutrophils, dendritic cells, natural killer cells, macrophages and then there is monocytes
What are some facilitated mediators of inflammation?
There are two classes such as
Plasma derived:
Clotting factor, kinin system , complement system
Cell derived or vasoactive mediators: which increase vasodilation and increase capillary permeability
These are cells such as WBC, platelets like serotonin and histamine, arachnoid acid stimulates prostaglandins to then release in initial inflammation signs,
Immunity definition ⛑️
a physiologic process that provides an individual with protection or defense from
What are the antecedents for an acute inflammation? Cellular response
Chemotaxis
Cellular adherence
cellular migration
Chemotaxis
Bringing in cells for tissue repair to injury site , chemo tactic mediators : chemokines
What are the acute inflammation clinical manifestations?
5 cardinal signs and systemically are fever increasing and plasma proteins with leukocytes circulating
Laboratory/ diagnostic test to test
Inflammation
elevated WBC, white blood count differential (left shift, neutrophils proliferate)
Elevated C reactive protein, erythrocyte sedimentation rate, procalcitonin
Medicine: Aspirin
TC: anti inflammatory, anti platelet, NSAID,
PC: salicylate
Should not be given to children under 12 years or younger,
Attributes of chronic inflammation
Last longer than seven weeks, monocytes, macrophages and lymphocytes , create scarring tissue, causes immune suppression and risk of opportunistic infections
