Infertility/ED Flashcards
What’s expected of the semen analysis and hormone level in ejaculatory duct obstruction or CAVD
low semen volume, absent semen fructose, acidic semen (< 7.1) , low-normal FSH
What are the contraindications to PDE5 inhibitors?
MI w/i 6 months, retinitis pigments, nitrites
When is IUI considered?
sperm count between 5-40 million
What is the mechanism of action of clomiphene citrate and when is it indicated?
Estrogen modulator that increases intratesticular testosterone
Indicated in low to normal T and NOA
What are the treatments for stuttering priapisms
alpha adrenergic (ex. psuedoephedrine) anti androgens (ex. bicalutamide) LH-RH antagonists/agonists PDE 5 inhibitors Beta 2 agonist (terbutaline)
what are the products of spermatogenesis?
spermatogonium -> primary spermatocyte (2n) (mieosis I) -> secondar spermatocyte (1n) (meiosis II) -> spermatid -> spermatozoa
What do you do if motility is low but viability test is normal?
Ultrasound to rule out obstruction since can also affect motility
What are the characteristics of obstructive azoospermia?
low semen volume
acidic semen
absent seminal fructose
poor motility
when do you obtain microdeletion test?
when sperm concentration < 5
What condition does this describe:
Hypogonadtropic hypogonadism
Anosmia, hypotrophic testicles
Kallman’s syndrome
What condition does this describe:
Hypergonadtropic hypogonadism
gynecomastia, tall, eunuchoid, infertile (NOA), testicular atrophy, T:E2 imbalance
Kleinfelter’s
What is the significance of DNA fragmentation?
controversial for now no significance
What tumor is more likely in Klinefelter’s syndrome?
Leydig and sertoli cell
Breast cancer
What are the advantages of a two piece pump compared to a three piece? what are the disadvantages?
Advantages: No reservoir, requires less pumps,
Disdvantages: requires larger incision, less natural
What is most predictive of paternity in spina bifida patients?
sacral nerve level lesion of lesion at L5
