Infertility Flashcards

1
Q

What percentage of couples will concieve naturally within one year and two years respectively ?

A

First year: 85%

Second year: 94%

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2
Q

On what day in a normal 28 day cycle does ovulation occur?

A

Day 14

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3
Q

How do you calculate when ovulation is occuring in a non-standard cycle length?

A

Take 14 away from cycle length e.g. 35 day cycle, ovulation will occur on day 21

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4
Q

How is male factor infertility diagnosed?

A

2 semen analyses 2-3 days apart with total abstinence inbetween. If abnormal sperm are detected, the test is repeated in 3 months.

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5
Q

What is the likely cause of oligozoospermia, asthenazoospermia and teratozoospermia (known as OATs)?

A

Anabolic steroid use causing hypogonadotrophic hypogonadism.

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6
Q

What is the most common cause of male facter infertility?

A

Idiopathic causes - unidentifiable

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7
Q

What are the three possible managements for male factor infertility?

A

If sperm are present: intracytoplasmic sperm injection

If sperm are absent: percutaneous sperm aspiration OR sperm donation

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8
Q

What is the most common cause of couple infertility?

A

Male factor infertility

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9
Q

What are the 3 identifiable causes of couple infertility?

A
  1. Male factor infertility
  2. Ovulatory disorders
  3. Pelvic pathology
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10
Q

What are the 3 ovulatory disorders causing infertility?

A
  1. Hypothalamic or pituitary dysfunction (including weight loss)
  2. PCOS
  3. Primary ovarian insufficiency
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11
Q

What are the four pelvic pathologies causing infertility?

A
  1. PID
  2. Endometriosis
  3. Fibroids
  4. Previous surgery or infection
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12
Q

How is pelvic pathology related infertility investigated?

A

Hysterosalpingography
Hysterosalpingo-contrast-ultrasonography
Laparoscopy

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13
Q

What is the first line treatment for unexplained infertility and at what time should this be commenced?

A

IVF: after 2 years of trying to concieve

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14
Q

Which group of women are particularly at risk of ovarian hyperstimulation syndrome?

A

Woman with PCOS

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15
Q

What is the cause of ovarian hyperstimulation syndrome?

A

High dose gonadotrophins used in IVF to trigger egg production

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