Infertility Flashcards
Define Infertility
Failure to conceive after 1 year of unprotected intercourse in women less than 35 years of age and after 6 months in women 35+
Lifestyle Factors Associated with Increased Risk of Infertility
Environmental & occupational Toxic effects of tobacco, marijuana Excessive exercise Inadequate diet (extreme weight loss or gain) Advanced age
Factors Associated with Infertility
Male factor Ovulatory dysfunction Tubal damage Endometriosis Coital problems Cervical factor Unexplained
Female Factors Associated with Infertility
Cervical Uterine Ovarian Tubal Peritoneal
Cervical Factors Associated with Infertility
Stenosis
Abnormality of the mucus-sperm interactions
Uterine Factor Associated with Infertility
Congenital or acquired defects may affect endometrium or myometrium
Ovarian Factor Associated with Infertility
Ovulatory dysfunction
Tubal Factors Associated with Infertility
Abnormalities or damage to fallopian tube
Congenital or acquired
Peritoneal Factors Associated with Infertility
Anatomic defects
Physiologic dysfunctions
Types of Physiologic Dysfunctions Associated with Infertility
Infection
Adhesions
Adnexal masses
Endometriosis
Male Factors Associated with Infertility
Pre-testicular
Testicular
Post-testicular
Pre-testicular Factor Associated with Infertility
Congenital or acquired diseases of the hypothalamus, pituitary, or peripheral organs that alter the hypothalamic pituitary axis
Ex: prolactinoma
Testicular Factors Associated with Infertility
Genetic: Klinefelter
Non-genetic: marijuana, radiation, varicoceles
Post-testicular Factors Associated with Infertility
Congenital or acquired factors that disrupt normal transport of sperm through the ductal system
Examples of Post-Testicular Factors Associated with Infertility
CF Chlamydia Gonorrhea Trauma Surgery Lack of vas deferent on one side
Evaluation of Infertility
Complete eval performed according to the woman’s menstrual cycle
History in the Evaluation of Infertility
Copy of previous medical records
Complete medical history questionnaire
Details regarding type of infertility
Hx of previous pregnancies & outcomes
Hx of previous infertility eval/treatment
Female menstrual history, frequency & patterns since menarche
Male medical history of any previous semen analysis
Couple’s history of STDs
Couple’s current medical treatment, reason, & history of allergies
Complete ROS to identify endocrine or immunologic reasons