Infective Endocarditis Flashcards
Clinical Features
Hand: Clubbing, Splinter Haemorrhages, Janeway lesions, Osler’s nodes
Chest: changing heart murmur
Abdominal: Splenomegaly, Microscopic haematuria ( emboli to the kidneys)
Causes
Most common in developing countries
Developed countries
Indwelling lines
Colorectal cancer
Streptococcus viridans was the most common cause of infective endocarditis. This is no longer the case, except in developing countries.
Staphylococcus aureus is now the most common cause of infective endocarditis.
Staphylococcus epidermidis commonly colonize indwelling lines and are the most cause of endocarditis in patients following prosthetic valve surgery,
Streptococcus bovis is associated with colorectal cancer
Management
Pen allergic: Vancomycin
Staph Aureus: Flucloxacillin + gentamycin
Prosthetic vlave: + rifampicin
Strep viridans: benzylpenicllin + gentamycin
