Infective Endocarditis Flashcards

1
Q

What is infective endocarditis?

A

infection producing vegetations on the endocardium usually including the heart valves

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2
Q

In IE more common in men or women

A

men

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3
Q

Is IE a disease of the young or the elderly

A

Elderlu- more than 50% of cases occur in those over 60

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4
Q

What are the most commonly valves infected

A

Mitral (most common), Aortic

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5
Q

What is the most common cause of IE

A

Staph aureus or strep viridins

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6
Q

What type of IE do immunocompromised and IV drug users get

A

Fungi

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7
Q

Risk factors of IE

A
Prosthetic heart valve
Structural heart disease
Poor dentition
IV drug user
Pregnant
Diabetes
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8
Q

Presentation when infected with staff aureus

A

Acute bacterial, severe illness progresses over days to weeks

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9
Q

Presentation with streptococci

A

subacute bacterial, mild-moderate that progresses slowly over weeks to months

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10
Q

When Might you see endocarditis infecting the tricuspid valve

A

Right sided endocarditis- IV drug users

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11
Q

What percentage of prosthetic valve patients get IE within the first year

A

1-2%

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12
Q

Clinical manifestations

A
Fever of unk origin
Weight loss
New cardiac murmur
Petechia
Splinter hemorrhages
Roth spots
Osler nodes
Janeway lesions
Night sweats
Fatigue
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13
Q

If the vegitation dislodges where will it go

A

Septic embolism- heart, brain, kidney, spleen, liver and extremitis

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14
Q

Diagnosis of IE

A

Min 3 blood cultures

TEE- 50-80% have vegetation

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15
Q

What is the duke criteria

A

Uses minor and major criteria

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16
Q

Treatment of IE

A

High dose IV antibiotics for 2-6 weeks, surgery if bad enough

17
Q

Who gets prophylaxed

A

Only patients with mitral valve prolapse with REGURITATION

18
Q

When do you prophylax

A

Dental proceedures, resiratory tract with biopsy, GI or urology proceedures

19
Q

What is the antibtiotic prophylaxis

A

amoxicillin 2 grams orally 30-60 mins before the procedure

or Keflex or azithromycin for pen allergic