Infectious Viral Disease Flashcards
period of contagiousness of Rubeola
3 days before up to 4-6 days onset of rash
Pathognomonic sign of measles
warthin finkeldey giant cells:exanthem
Incubation period of measles
8-12 days high grade fever
Clinical features of measles
cough, coryza and conjuctivitis with photophobia
In measles this sign appers 1-4 days prior to the onset of rash that can be seen at the level of the premolars
Koplik spot
Mannner of appearance of rash in measles
cephalocaudal which starts with forehead, behind the ear, upper neck and confluence in the torso
Describe the rash of measles
maculopapular rash
most common complication of measle
otitis media
Vitamin recommendation for child with measles and the dose
VItamin A supplementation single dose
200,000 >1y/o
100,000 6mos-1y/o
50,000 <6mos
what is the most common cause of death in patients with measles
Pneumonia
A chronic complication of measles, a delayed onset with fatal outcome, which affects the CNS
Subacute sclerosing Panencephalitis
What virus causes measles?
paramyxovirus
What virus affects Rubella
togaviridae
This is a 3 day virus that can usually transmitted transplacentally which causes fetal damage
Rubella
Viral shredding of rubella
nasopharynx begins at 10 days after infection and detected upto 2 weeks following the onset of rash
What it the period of highest communicability of rubella
5 days before to 6 days after the appearance of rash
what is the incubation period of rubella
14-21 days
patient with low grade fever, sorethroat , red eyes with or without pain, and lymphadenopathy
rubella
Characteristic of rash(Rubella)
non distinctive, centrifugal, no desquamation that last for 3 days
This is a petechial hemorrhage on the soft palate which coincide with the onset of rash
forchheimer spots
What are the complications of rubella
thrombocytopenia, arthritis, encephalitis
Babies born with congenital rubella can shred up to how many days/months
1 year via respiratory secretions
what are the timing of vaccine (MMR) for rubella
2 doses
1st dose:12-15mos
2nd dose:4-6 years
What is the etiology of VZV?
herpes virus
incubation period ov VZV
10-21 days
what is the manner of appearance of rash in VZV?
appears first on the scalp, face the trunk( centripetal)
What disease has clounding and umbilication which begins at 24-48 hr
Varicella zoster virus
10-year-old patient calls his parents from summer camp to state that he has had fever, muscular pain in the neck, headache, and malaise. He describes the area from the back of his mandible toward the mastoid space as being full and tender and that
his earlobe on the affected side appears to be sticking upward and outward. Drinking sour liquids causes much pain in the affected area. When his father calls your office, you remind him that he had refused immunizations for his child on religious grounds. Which of the following preventable diseases has this child acquired?
a. Mumps
b. Varicella
c. Rubella
d. Measles
mumps
A 2-month-old child of an HIV-positive mother is followed in your pediatric practice. Which of the following therapies should be considered
for this child?
a. Monthly evaluation for Kaposi sarcoma
b. Prophylaxis against Pneumocystis jiroveci pneumonia (Pneumocystis carinii)
c. Vitamin C supplementation
d. Oral polio virus vaccine
e. Bone marrow transplantation
Prophylaxis against Pneumocystis jiroveci pneumonia (Pneumocystis carinii)
A 10-month-old infant on long-term aspirin therapy for Kawasaki disease develops sudden onset of high fever, chills, diarrhea, and irritability.
A rapid swab in your office identifies influenza A, adding her to the long list of influenza patients you have seen this December. Over the next few
days, she slowly improves and becomes afebrile. However, 5 days after your last encounter you hear from the hospital that she has presented to
the emergency center obtunded and posturing with evidence of liver dysfunction. Which of the following statements about her current condition
is correct?
a. With proper supportive care, the overall mortality rate is low.
b. With her progressive liver dysfunction, increased total serum bilirubin is anticipated.
c. Administration of N-acetylcysteine is first-line therapy
d. Seizures are uncommon with this condition.
e. Death is usually associated with increased intracranial pressures and herniation.
e. Death is usually associated with increased intracranial pressures and herniation.
an acquired mitochondrial hepatopathy results from the interaction of an influenza (or varicella) infection and aspirin use
Reye syndrome
An 18-month-old child presents to the emergency center having had a brief, generalized tonic-clonic seizure. He is now postictal and has a
temperature of 40°C (104°F). During the lumbar puncture (which ultimately proves to be normal), he has a large, watery stool that has both
blood and mucus in it. Which of the following is the most likely diagnosis in this patient?
a. Salmonella
b. Enterovirus
c. Rotavirus
d. Campylobacter
e. Shigella
e. Shigella
A 2-year-old child is admitted to your hospital team. The child’s primary care doctor has been following the child for several days and has
noted her to have had high fever, peeling skin, abdominal pain, and a bright red throat. You are concerned because two common pediatric
problems that could explain this child’s condition have overlapping presenting signs and symptoms. Which of the following statements comparing
these two diseases in your differential is true?
a. Neither has a cardiac complication.
b. Serologic tests are helpful in diagnosing both.
c. Only one of the diseases has mucocutaneous and lymph node involvement.
d. Pharyngeal culture aids in the diagnosis of one of the conditions.
e. A specific antibiotic therapy is recommended for one of the conditions, but only supportive care is recommended for the other
d. Pharyngeal culture aids in the diagnosis of one of the conditions.
Erythrogenic toxin-producing group A ß-hemolytic streptococci is the agent responsible for scarlet fever
and rise in antistreptolysin O titer
A 2-year-old child is admitted to your hospital team. The child’s primary care doctor has been following the child for several days and has
noted her to have had high fever, peeling skin, abdominal pain, and a bright red throat. You are concerned because two common pediatric
problems that could explain this child’s condition have overlapping presenting signs and symptoms. What is your possible differential diagnosis
kawasaki disease
scarlet fever
What is the most serious complication of kawasaki disease?
Coronary Artery aneurysm
A patient with hair loss complaint with the lesion does not fluoresce with a Wood lamp and has not responded well to a variety of topical
agents. The lesion is boggy, is spreading, and has tiny pinpoint black dots throughout. Which of the following courses of action is most
appropriate for this child?
a. Instruct mom to keep all hair braids loose rather than tight against the scalp
b. Initiate griseofulvin therapy
c. Ultraviolet light therapy and intradermal steroid injection
d. Supplement diet with biotin
e.Obtain thyroid function studies
b. Initiate griseofulvin therapy