Infectious Diseases w/o Vaccines Flashcards

1
Q

Measles:

  • Virus
  • SxS
  • Complications
  • Tx
A
Virus: Morbillivirus
SxS:
-Cough, choryza and conjunctivitis
-Koplik spots:
-Exanthem: Rash appears 3-5days after fever. Begins at hairline and spreads down body 

Complications: Pneumonia, Encephalitis

Tx: Supportive & prevent that ish with the MMR vaccine

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2
Q

Mumps:

  • Virus
  • SxS
  • Complications
  • Tx
A

Virus: Paramyxovirus

SxS: Parotitis & Orchitis

Complications: sub-fertility

Tx: Prevent that ish with the MMR vaccine

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3
Q

Rubella

  • Virus
  • SxS
  • Complications
  • Tx
A

Virus: Togavirus

SxS:

  • Descending rash - “blueberry muffin”
  • Post auricular and posterior lymphadenopathy

Complications:
-Congenital Rubella: Deafness, Autism, Cataracts and glaucoma, Heart defects (PDA), Low birth weight, Psychomotor retardation

Tx: Prevent that ish with the MMR vaccine

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4
Q

Diphtheria

  • Virus
  • SxS
  • Complications
  • Tx
A

Virus: Corynebacterium diphtheria

SxS:

  • Cervical lymphadenopathy
  • Pseudomembrane: friable, grey/white membrane on pharynx that bleeds with scraping

Complications:

  • Airway obstruction
  • Myocarditis
  • Paralysis
  • Death

Tx:

  • Diphtheria antitoxin + Antibiotics (Erythromycin or Penicillin)
  • Place on respiratory droplet isolation
  • Prevent with DTap
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5
Q

Pertussis

  • Virus
  • SxS
  • Complications
  • Tx
A

Virus: Bordetella pertussis

SxS

  • Catarral Stage (1-2wks): Runny nose, sneezing, low grade fever, cough that worsens
  • Paroxysmal Stage (1-6wks): Paroxysms of coughing and posttussive vomiting. Inspiratory “whoop” is classic but not always present. Cyanosis and difficulty breathing
  • Convalescent Stage (weeks to months): Gradual recovery

Complications: Apnea, Secondary pneumonia, Seizures, Encephalopathy, Death

Tx: Azithromycin. DTap

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6
Q

Tetanus

  • Virus
  • SxS
  • Complications
  • Tx
A

Virus: Clostridium Tetani

SxS:

  • Muscle rigidity
  • Trismus: ”Lock jaw”
  • Muscle spasms: Sudden, involuntary muscle tightening
  • Painful muscle stiffness all over the body
  • Trouble swallowing
  • Jerking or staring (seizures)
  • Headache
  • Fever and sweating
  • Changes in blood pressure and tachycardia

Complications: Laryngospasm, Fractures, Seizures, Death

Tx: DTap

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7
Q

What is the leading cause of hospitalizations in infants and younger children <2yo and why?

A
Bronchiolitis
Due to:
- Hypoxemia
- Respiratory compromise
- Dehydration/difficulty feeding
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8
Q

Your patient who attends daycare comes in for 1-3 days of a runny nose and cough. The parent states that the symptoms are becoming worse. On auscultation, you hear wheezing, rales, and rhonci. What is the most likely diagnosis and how would you treat it?

A

Bronchiolitis.

MC caused by RSV or Rhinovirus.

Tx: self-limiting usually. Saline + Suction.

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9
Q

Under what circumstances would you admit a patient with bronchiolitis?

A
  • Increased work of breathing
  • Breathing >60 times a minute
  • Retractions
  • Nasal flaring or grunting
  • Cyanosis and hypoxia
  • Dehydration or Refusal to drink
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10
Q

If you were to order a CXR for bronchiolitis, which isn’t usually necessary, what would you find?

A

Hyperinflation
Peribronchial thickening
Segmental atelectasis
Increased AP diameter

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11
Q

What age groups are croup and epiglottitis found?

A

Croup: 6 months - 3 years
Epiglottitis: 6-12 yo

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12
Q

A 2yo patient comes in with a cough that worsens at night. What is the most likely diagnosis and how would you treat it?

A

Croup: the cough would be described as barky.
Tx: Dexamethasone + Racemic epinephrine if resting stridor –> monitor for 2 hours after

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13
Q

What would you find on CXR in a patient with croup?

A

Steeple Sign - subglottic narrowing

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14
Q

What are the MC organisms that cause epiglottitis?

A

H. Flu
Strep. pneumo
S. aureus
B-hemolytic streptococci

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15
Q

Your patient comes in with difficulty breathing and stridor. When they speak, their voice is muffled and they complain of difficulty swallowing. What is the most likely diagnosis and how would you treat it?

A

Epiglottitis

Tx: ED transfer for airway management!!!

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16
Q

What are the main clinical features of a pt with epiglottitis?

A

Drooling
Dysphagia
Dysphonia
Distressed respiratory effort

Tripoding!

17
Q

What diagnostic measurements would you take to confirm a dx of epiglottitis?

A

Laryngoscopy is definitive due to direct visualization, but it can only be done on a stable patient.

Lateral Neck XR: thumb print sign

18
Q

What is contraindicated in a distressed patient with epiglottitis?

A
  • Do NOT attempt to examine throat or use tongue blade

- Do NOT obtain initial labs or X-ray

19
Q

Define the differences between wheezing and stridor.

In which disease processes are wheezing and stridor found?

A

Wheezing:

  • Intrathoracic = lower airway obstruction
  • Continuous whistling sound heard more on expiration
  • Disease: Bronchiolitis

Stridor:

  • Extrathoracic = upper airway obstruction
  • High pitched sound, heard more on inspiration
  • Croup & epiglottitis
20
Q

When should patients expect the worst of the symptoms to start in those who have bronchiolitis?

A

Days 3-5

21
Q

When are patients with bronchiolitis most contagious?

A

1st week but can remain contagious for up to 4 weeks if they’re really young or if they have risk factors

22
Q

Which virus most commonly causes croup?

A

Parainfluenza Type 1