Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

OB/GYN - CSE > Infectious Diseases in Pregnancy > Flashcards

Infectious Diseases in Pregnancy Flashcards

1
Q

Common sequela of maternal-fetal infections

A
  • Premature Delivery
  • CNS abnormalities
  • Anemia
  • Jaundice
  • Hepatosplenomegaly
  • Growth restriction
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Congenital toxoplasmosis syndrome

A
  • Triad: Hydrocephalus, Intracranial calcifications, Chorioretinitis
  • Ring-enhancing lesions on MRI
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Toxoplasmosis diagnosis

A

Not routine; Serologic testing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Toxoplasmosis treatment

A

Pyrimethamine + sulfadiazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Toxoplasmosis prevention

A

Avoid exposure to cat feces or uncooked meat during pregnancy; spiramycin prophylaxis for the third trimester

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Congenital rubella syndrome

A
  • Purpuric “blueberry muffin” rash
  • Cataracts, congenital glaucoma
  • Mental retardation, microcephaly
  • Hearing loss (most common single defect)
  • PDA
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Rubella diagnosis

A

Serologic testing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Rubella prevention

A

Immunize before pregnancy; vaccinate the mother after delivery if serologic titers remain ⊝

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Congenital CMV syndrome

A
  • Chorioretinitis
  • Periventricular calcifications
  • Microcephaly; Mental and motor retardation
  • Hemolytic anemia
  • Sensorineural deficits (e.g. hearing loss)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

CMV diagnosis

A

Not routine: Urine culture, PCR of amniotic fluid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

CMV treatment

A

Postpartum gangciclovir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

HSV newborn symptoms

A

Skin, eye, and mouth infections
Life-threatening CNS/systemic
infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

HSV diagnosis

A

Not routine; Serologic testing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

HSV treatment

A

Acyclovir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

HSV prevention

A

Perform a C-section if lesions are present at delivery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

HIV diagnosis

A

ELISA, Western blot

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

HIV treatment

A

HAART

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

HIV prevention

A

AZT or nevirapine in pregnant women with HIV; perform elective C-section if viral load is > 1000
Treat infants with prophylactic AZT; avoid breastfeeding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Syphilis fetal symptoms

A
  • Maculopapular skin rash
  • Lymphadenopathy
  • Hepatomegaly
  • “Snuffles”: mucopurulent rhinitis
  • Osteitis
  • Late congenital syphilis:
    • Saber shins
    • Saddle nose, frontal bossing, short maxilla, high palatal arch
    • CNS involvement
    • Hutchinson triad: peg-shaped central incisors, deafness, interstitial keratitis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Syphilis diagnosis

A

Dark-field microscopy, VDRL/RPR, FTA-ABS/MHA-TP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Syphilis treatment

A

Penicillin (if allergic, should desensitize and give penicillin)

22
Q

Syphilis prevention

A

Penicillin in pregnant women who test ⊕

23
Q

Infections more common in pregnancy and puerperium

A

Pyelonephritis, endomyometritis, mastitis, toxic shock syndrome

24
Q

Infections whose complications increase during pregnancy

A

UTIs, bacterial vaginosis, surgical wounds

25
ABS/UTI complications in pregnancy
Preterm birth, low-birth-weight infants; bacteremia, sepsis, adult ARDS for mother
26
Weeks of gestation in which routine urine culture is used to screen ASB
12-16 weeks (1st trimester)
27
Acute cystitis syndrome
Urgency, frequency, dysuria and suprapubic discomfort
28
First line antibiotics in ASB/UTIs in pregnancy
Penicillins or cephalosporins
29
Treatment when patient has dysuria or bladder pain
Phenazopyridine
30
BV complications in pregnancy
Preterm premature rupture of membranes (PPROM), preterm delivery, puerperal infections (chorioamnionitis and endometritis)
31
Amsel criteria (3 out of 4)
1) vaginal discharge 2) whiff test (10% KOH) positive 3) ph > 4.5 4) clue cells > 20%
32
BV treatment in pregnancy
Oral metronidazole (or clindamycin) for 1 wk
33
Weeks of gestation in which routine vagina/rectal swab culture is performed to screen for GBS
35-37 weeks
34
GBS prophylaxis in pregnancy
IV penicillin G (or ampicillin) at time of labor or ROM
35
GBS complications in pregnancy
Neonatal sepsis; UTIs, PROM, chorioamnionitis and endomyometritis
36
Chorioamnionitis complications in pregnancy on neonate
Neonatal respiratory distress, pneumonia, meningitis, periventricular leukomalacia, cerebral palsy
37
Chorioamnionitis complications in pregnancy on mother
Uterine atony, postpartum hemorrhage, need for cesarean, endomyometritis, septic shock
38
Diagnosis of Triple I
High index of suspicion, fever >39°C or 102.2°F (oral temp) + another sign (↑ WBC [>15k/mL], purulent fluid, fetal tachycardia [>160 bpm]) or ⊕ amniocentesis culture
39
Treatment of chorioamnionitis
IV antibiotics (2/3rd gen cephalosporins or amp/genta) and delivery of fetus
40
Varicella syndrome (transplacental in first trimester)
- Skin scarring and limb hypoplasia - Chorioretinitis - Microcephaly (cerebral cortical atrophy) - Hydronephrosis
41
Neonatal varicella infection (acquired during labor) treatment
VZIG for passive immunity
42
Influenza vaccine
Given at any gestational age
43
Parvovirus B19 complications in fetus
Nonimmune hydrops (due to aplastic anemia), fetal death (abortion)
44
Parvovirus B19 infection in newborn
Erythema infectiosum or fifth disease
45
Most common cause of perinatal infection
CMV
46
Most common cause of congenital hearing loss
CMV
47
Most common cause of chorioamnionitis
GBS
48
GBS prophylaxis in pregnancy does not prevent
Late-onset (1wk - 3m) disease, usually meningitis
49
Most common cause of ophthalmia neonatorum
Chlamydia trachomatis
50
Hepatitis B prevention
Vaccine to mother during pregnancy; HBIG and vaccine to infant upon delivery
51
Neonatal HPV infection
Juvenile-onset respiratory laryngeal papillomatosis (due to HPV-6 and 11)
52
Infections associated with preterm delivery
Gonorrhea, Trichomoniasis, BV

OB/GYN - CSE (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions