Infectious Diseases And Anti-Infectives Flashcards
Tx for necrotising fasciitis (ALL)
M-eropenem
V-ancomycin
C-lindamycin
Strep pyogenes confirmed B-enzylpenicillin C-lindamycin PLUS normal immunoglobulin
Endocarditis Tx Native valve Empirical Tx Prostatic valve and MRSA Empirical Tx Hypersensitivity to penicillin Directed enterococcus Tx
Native Valve Empirical Tx
Gentamicin +
Benzylpenicillin +
Flucloxicillin
MRSA Empirical Tx & Prosthetic Valve Empirical Tx
Gentamicin +
Vancomycin +
Flucloxicillin
If immediate sensitivity to penicillins:
Gentamicin +
Vancomycin
Directed- enterococcal Gentamicin PLUS EITHER Benzylpenicillin OR Amoxicillin/ampicillin
What does TB Tx consist of?
Combination and prolonged therapy
TB Tx and duration
Isoniazid 6 months
Rifampicin 6 months
Ethambutol 2 months
Pyrazinamide 2 months
Bacterial gastroenteritis empirical Tx
Ciprofloxacin
OR
Norfloxicin 400mg 12-hourly 3 days
Campylobacter enteritis Tx
Azithromycin OR ciproflox OR norflox
Cholera tx
Azithromycin AS A SINGLE DOSE
OR
ciproflox AS A SINGLE DOSE
Salmonella Tx
If AB are required:
Azith
OR
ciproflox
Shigellosis Tx
Ciproflox OR Norflox OR Co-trimoxazole
Travellers diarrhoea Tx
Mild: no AB just rehydration, +/- anti motility drugs, usually self limiting Moderate or severe: rehydration 2-3L/day azithromycin OR norfloxacin
What are the two parasitic infections of the GIT?
Amoebiasis
Giardia
Ameobasis Tx
Tindazole OR 2. Metronidazole Then administration of a luminal agent to eradicate cysts and prevent relapse Paromomycin
Giardia Tx
Water borne
- Tindazole OR
- Metronidazole
Empirical Tx for bacterial meningitis
Hypersensitivity incl
Dexamethasone PLUS EITHER Ceftriaxone OR cefotaxime
If listeria is suspected or immunocompromised, pregnant, >50 years etc. ADD
Benzylpenicillin to the above regimen
Hypersensitive immediate
Vanc
PLUS
Ciproflox
OR
2. Moxiflox as monotherapy
Direct therapy neisseria minigitidis
Benzylpenicillin
Immediately hypersensivity
Ciproflox