infectious diseases Flashcards

1
Q

what does RILE stand for with regards to the heart

A

right murmurs loudest on inspiration, left murmurs loudest on expiration

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2
Q

Which valve does the patient lean forward for

A

Aortic

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3
Q

Which valve does the patient lean to the side for

A

mitral

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4
Q

Features of atypical pneumonia

A

dry cough, malaise, fever, joint pain, longer history

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5
Q

key things in cardiology exam

A

parasternal heave LHS, check for thrills over each valve

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6
Q

What does stoney dull indicate

A

pleural effusion

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7
Q

Things to remember from cardio exam that you need in resp

A

JVP and apex beat

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8
Q

Ptosis on respiratory exam

A

Horners syndrome, pancoast tumour

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9
Q

fever definitions

A

Continuous fever - fluctuates within 1 degree but remains high
Intermittent - fluctuates between baseline and high
Remittent - there is fluctuation but always 1 degree above baseline at least

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10
Q

systems review

A

CNS headache, seizures, neck stiffness, photophobia, vision changes. Skin - colour changes, rash, pruritis, tenderness. MSK - joint pain or mobility issues. GI- stool problems, abdominal pain. Resp- cough, SOB. Cardiac - chest pain, palpiatation, SOB. Urinary - dysuria, anuria, discharge, flank pain. Red flags- lumps and bumps, malignancy, fever, rash, weight loss, sweats. Metabolic - heat or cold intolerance, mood changes.

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11
Q

In general examination always mention

A

pulses

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12
Q

Jaundice associations -

A

changes in colour of urine and stools, itching of skin, dull achy pain in right hypochondrium, vomiting

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13
Q

Haemolysis history

A

= chills and back pain, blood problems, sickle cell, G6PH etc

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14
Q

Liver disease stigmata =

A

rectal varices, skin

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15
Q

investigation for TB patient

A

CXR and bronchoscopy

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16
Q

pyelonephritis treatment

A

co-amox IV

17
Q

treatment for line infection with coagulating neg staph (neutropenic sepsis)

A

IV tazocin

18
Q

What does this show

A

gametocyte = malaria

19
Q

What does this show

A

Area of consolidation could be pneumonia in apex of right upper zone with effusion of horizontal fissure

20
Q

organism and treatment

A

Group A streptococcus - gram positive cocci chains
IV benzylpenicillin/Flucloxacillin would be the appropriate choice

21
Q

response to penicillin allergic reaction anaphylaxis

A

Allergic reaction - anaphylaxis to antibiotic
IM adrenaline 0.5mg in 500ml
Antihistamine, salbutamol nebulised, steroid treatment e.g. hydrocortisone

Stop antibiotic treatment

22
Q

Falciparum malaria =

A

headphones on blood film (treatment is artemisinin (IV artesunate and PO Riamet)

23
Q

Dengue features

A

Dengue = classically presents with rash
* Lasts 1-5 days
* Improves 3-4 days after rash
* Supportive treatment only
* Re infection can be dangerous

24
Q

Fever, headache +/- abdo pain (dry cough) =

A

Fever, headache +/- abdo pain (dry cough) = Typhoid and paratyphoid/enteric fever (most common in Leic), faecal-oral (salmonella typhi)
* Invades Payer’s patches not mucosa (hence not necessarily diarrhoea)
* Low infectious dose, survives gastric acid, reside within macrophages
* Incubation 7-14 days
* 10% mortality
* +tive blood culture
* Treat with IV ceftriaxone or azithromycin (Meropenem if Ceftriaxone resistance)
* Takes 7-10 days to settle even with antibiotics

25
Difference between meningitis and encephalitis
Meningitis is inflammation of the meninges surrounding brain and spinal cord, encephalitis is inflammation of the brain itself Meningitis: fever, headache, vomiting, photophobia, stiff neck Encephalitis: altered consciousness, seizures and focal deficits
26
Immediate management of meningitis
Single dose of parenteral benzylpenicillin IV/IM Corticosteroids Paracetamol for temperature Oxygen/fluids/pain relief if indicated
27
Investigations to confirm meningitis diagnosis
Blood culture CT scan Spinal tap - cerebrospinal fluid culture
28
Examples of notifiable diseases
Botulism, legionnaires disease, measles, TB
29
CSF result in meningitis that is bacterial
CSF results: Increased opening pressure, high protein, high WBC count between 10-10,000, decreased glucose concentration <45 mg/dL, cloudy
30
What infectious disease are associated with patients travelling to sub saharan africa
HIV, TB, malaria, schistosomiasis
31
Most likely parasitic infection from sub saharan africa
Schistosomiasis - microscopic visualisation of eggs in stools or urine, or serological testing of affected tissues for detection Treat with praziquantel
32
Types of TB
TB meningitis/CNS TB, pericardial TB, Miliary TB, pulmonary TB
33
TB meningitis key points
TB meningitis. MRI would show leptomeningeal enhancement. LP will show high protein, low glucose and lymphocytosis Given steroids when starting treatment and treatment is longer (12 months)
34