Infectious Diseases

Question 1

All viruses have protein coat or shell surrounding thier genome. Name it.

Answer 1

Capsid

Question 2

The genome of a virus contains______or______. And it can either be______stranded or______standed.

Answer 2

• RNA or DNA

* Single-stranded or Double-stranded

Question 3

What is a naked capsid virus?

Answer 3

It does not contain an envelope

Question 4

What 2 types of nucelocapsid due viruses form

Answer 4

icosahedron or helix

Question 5

Are viruses with envelopes more or less susceptible to environmental drying or chemical disruptions?

Answer 5

More susceptible

Question 6

Name the 8 phases of virus replication. Starting from attachement and ending with budding/lysis. When does the Eclipse phase occur? What is the Eclipse Phase?

Answer 6

Attachement Penetration Uncoating - eclipse phase begins because the virus can not be seen. Synthesis Translation Replication Assembly Budding or Lysis

Question 7

What is tropism in virology?

Answer 7

Tropism determines which host cells a virus can infect. It is determined by cell receptors and viral glycoproteins.

Question 8

What is latency in virology?

Answer 8

Latency is when a virus infects a host cell and becomes quiescent (dormant) with little-to-no genomic replication or protein production.

Question 9

Name 5 viral disease states

Answer 9

• Acute (flu)
• Acute w/ novel disease manifestations later in life (measles–>SSPE)
• Latent infection (shingles)
• Persistant in Host, but latent with occasional reactivation (herpes)
• Chronic Infection (hepititis, HIV)

Question 10

What is the process by which a host cell becomes immortalized and potentially cancerous as a result of a viral infection.

Answer 10

Transformation