Infectious diseases Flashcards

1
Q

What infections are prone to reactivation in patients with HIV?

A

Toxoplasma gondii
Myocbacterium tuberculosis

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2
Q

What is dapsone? How does it work? What are its side effects? What do you need to test before giving it?

A

An antimycobacterial. Probably acts through inhibition of folate synthesis. It’s used to treat dermaitis herpetiformis as well as leprosy.

Important unwanted adverse effects: haemolysis (life threatening if G6PD deficient patient), methaemoglobinaemia, anorexia, nausea and vomiting, fever, allergic dermatitis, neuropathy.

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