Infectious Disease questions Flashcards

1
Q
Which of the following is the most accurate test for infectious disease?
A-protein levels
B-culture
C-IgM levels
D-Gram stain
A

B-culture

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2
Q
Which of the following anabiotic's will cover MRSA?
A-nafcillin
B-cefozollin
C-piperacillin-tazobactam
D-ceftaroline
E-azithromycin
A

D- ceftaroline (only cephalosporin that will)

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3
Q
Which of the following is most likely to be effective for Morganella or Citrobacter?
A-tedizolid
B-dalbavancin
C-ertapenem
D-oritavancin
E-erythromycin
A

C- ertapenem

All the others are for gram +

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4
Q
What is the best broad-spectrum coverage for anaerobic G.I. bacteria?
A-aztreobam
B-piperacillin/tazobactam
C-oxacillin
D-cefipime
E-doxy
F-vanc
A

B-piperacillin-tazobactam. Only one listed that covers anaerobes. The penems will as well

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5
Q

What is the best anabiotic for E. coli bacteremia?
A- vancomycin
B- linolezid
C- quinolones/aminoglycosides/penems/aztreonam
D-doxy
E-oxacillin

A

C

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6
Q
What is the best way to confirm meningitis with a false negative culture?
A-gram stain
B-glucose level
C-latex agglutination test
D-protein level
A

C. Latex agglutination tests wont change after a few doses of abx

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7
Q
What is the next step in managing a patient with meningeal signs and focal neuro deficits?
A-ceftriaxone, vanc and steroids
B-head CT
C-ceftriaxone
D-neuro consult
E- steroids
A

A- just treat in a clear-cut case

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8
Q
What is the most accurate test of herpes encephalitis?
A-brain biopsy
B -PCR of CSF
C-MRI
D-tzank prep
E-serology
A

B. PCR is most accurate. Serology is useless.

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9
Q
What is the next step in a patient on acyclovir for encephalitis with rising creatinine levels?
A-stop acyclovir
B-reduce dose and hydrate
C-switch to orals
D-switch to foscarnet
A

B- orals are insufficient and foscarnet is more renally toxic

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10
Q
What is the most sensitive finding for otitis media?
A-redness
B-immobility
C-bulging
D-decreased light reflex
E-decreased hearing
A

B- mobility essentially excludes OM

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11
Q
What is the most accurate diagnostic test for febrile sinusitis
A-sinus biopsy or aspirate
B-CT scan
C- x-ray
D- culture of the discharge
E-transillumination
A

A

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12
Q
What is the next most appropriate step in a patient who presents with febrilesinusitis
A-linezolid
B-ct scan
C- xray
D-amoxicillin/clav and a decongestant
E-erythromycin and a decongestant
A

D- treat empirically in a clear cut case.

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13
Q
Which is most accurate in determining diarrhea etiology?
A-recent history
B-frequency of bowel movements
C-blood in stool
D-stool odor
E-recent interstate travel
A

C- blood must mean invasive pathogen

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14
Q
Which best correlates with increased mortality likelihood in hepatitis?
A- bilirubin
B- PT
C- ALT
D-AST
E- alk phos
A

B- increased prothrombin time suggests fulminant liver failure

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15
Q
Which will become abnormal first after hep B infection?
A- bilirubin
B-e antigen
C- surface antigen
D- core IgM antibody
E-ALT
A

C

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16
Q
Which of the following most strongly correlates with viral replication?
A-bilirubin
B-e antigen
C-surface antigen
D-core IgM antibody
E-ALT
A

B (same as DNA polymerase)

17
Q
which shows a patient is no longer infective?
A-normal bilirubin
B-no e antigen
C no surface antigen
D- no core IgM
E-normal ALT
A

C- as long as there is surface antigen, there is replication

18
Q
Which suggests need for treatment for chronic disease? 
A bilirubin
B e antigen
C surface antigen
D core igM antibody
E ALT
A

B: e antigen is strongest indicator of viral replication

19
Q
Which most strongly suggests transmission to an unborn child?
A bilirubin
B e antigen
C surface antigen
D core IgM
E ALT
A

B

20
Q
What is the next step with new vesicular lesions?
A oral acyclovir
B topical acyclovir
C tzanck prep
D serology
E PCR
A

A: treat a clear cut case

21
Q
What is the most sensitive CSF test for neurosyphilis?
A VDRL
B RPR
C FTA
D stain
E dark field
A

C: only FTA confirms “not neurosyphilis”

22
Q
What is the next step with dysuria and many white blood cells in urine?
A nitrofurantoin x3
B nitrofurantoin x7
C urine cx
D us of urinary tract
E ct of urinary tract
A

A: treat obvious uti. Only need longer tx if anatomic abnormality

23
Q
What is the difference in treatment between prostatitis and cystitis?
A causitive organism
B duration of therapy
C use of urinalysis
D oral med efficacy
E iv med efficacy
A

B- prostatitis takes longer

24
Q
What is the next step after diagnosing c. Septicum endocarditis?
A colonoscopy
B TEE
C CT ABD
D repeat blood cx
E surgical valve replacement
A

A: like S. Bovis, has GI association