Infectious disease buzz words Flashcards
PANCE
Common illnesses d/t H. influenza
1 epiglottitis, #2 CAP, sinusitis and otitis media
Coxsackie A sxs
Hand/foot/mouth and aspetic meningitis
Tx of H. influenza
Beta lactams (amoxicilin); Epiglotitis/CAP/Meningitis tx = ceftriaxone (prophylaxis for close contacts with rifampin)
rabies prodrome
pain and parasthesia at initial bite site
Tx for cryptococcus
fluconazole if CD4 < 50 (aids defining illness)
oral hairy leukoplakia MC in…
HIV/immunocompromised pts
MCC of pericarditis
Coxsackie virus
Bird/bat droppings near cave
Histoplasmosis capsulatum
cat scratch disease organism
bartonella henselae
Kawasaki MC in which age group
kids<5yo
tx of small pox
supportive; isolation and vaccine for close contacts
Vector for Brucellosis
Farm animals (goats, cows, sheep) Also, ingestion of unpasteurized milk/cheese
common clinical manifestations of MAC
- Pulmonary infxn in immunocompetent (bronchiectasis), 2. Disseminated (in HIV pts), 3. Lymphadenitis in kids (cervical, submandibular and maxillary)
break bone fever
Dengue fever
Dx for osteomylitis
MRI is most sensative early, bone bx is gold standard. X-ray shows periosteal reaction
Adult presentation of rubella
arthritis and lymphadenopathy
coronavirus causes
atypical pneumonia
bubonic plague organism
Yersinia pestis
TX of rubella
NONE!!! MMR vaccine available (given after delivery if prego, HIV pts if CD4 >200)
5th dz complications in pts with sickle cell dz
aplastic crisis
common manifestions of chagas
acute (3wks-3mo) - asymptomatic or unilateral periorbital edema
Latent - cardiomyopathy, CHF, megacolon and megaesophagus
common manifestations of Leprosy
skin lesions with poorly defined boarders (coolest parts of the body, ie face, ears, wrists), loss of eyebrows/eyelashes, facial deformities and symmetric nerve involvement (stocking glove neuropathy)
Tx of Q fever
doxycycline (typically self limiting)
well-demarcated margins of cellulitis
erysipelas (MCC strep)
MCC gas gangrene
clostridium perfringens
Common sites of involvement for mycobacterium leprae
SF tissues (skin and peripheral nerves)
Complications of mumps
orchitis (unilateral), oophoritis, encephalitis and aseptic meningitis
smallpox sxs
flu like prodrome with severe head/back pain –> skin eruptions in the same stage simulataneously (palmar and plantar lesions common)
Hanatavirus MC in which location
SW united states (young healthy adults)
Rabies Resp phase
resp muscle paralysis –> death
bunon-pitting edema with sharp irregular margins extending peripherally BUT clearing centrally; limited to hands/fingers/webspaces
erysipeloid (erysipelothrix rhusiopathiae)
Rubella
German Measles
Head –> toe flaccid paralysis
botulism
Coxsackie B sxs
Dilated cardiomyopathy and MCC of pericarditis and pleurodynia
EBV is part of which family
Herpes (HHV 4)
post-exposure prophylaxis for subsequent rabies exposures
HDCV (Rabies vaccine) days 0 and 3
zoster vaccine given to
adults >60yo or if CD4 >200
MC locations for chagas
latin america and texas
Romana’s sign
unilateral periorbital swelling (seen in chagas dz)
Tx of Karposi sarcoma
HAART therapy (radiation prn)
what traits are protective against malaria
sickle cell dz and thalassemia traits
phases of rabies
prodrome, CNS phase and resp phase
Tx of gas gangrene
Penicillin
vector for lyme dz
ixodes deer tick, MC in northeast
Kernig sign
hip/knee bent 90 and painful knee extension
Hantavirus causes
hemorrhagic fever
Tx of toxoplasmosis
sulfadiazene + pyrimethamine (spiramycin if prego)
Prophylaxis give bactrim
MC sx of pinworm (enterobiasis)
nocturnal anal itching
Tx of dengue fever
volume support, pressors and TYLENOL (NOT NSAIDS) - reduce the bleeds
Dx of babesiosis
parasites within the RBC (pathognomonic tetrads)
most dangerous form of malaria
Falciparum
MCC of infectious blindness
chlamydia
Pain out of proportion
- nec fasc 2. intestinal ischemia 3. compartment syndrome
CI for smallpox vaccine
eczema, dermatitis and burns
Tzank smear showing multinucleated giant cells
HSV
Common sxs of mono (EBV)
fever, sore throat, POSTERIOR cervical lymphadenopathy, malaise, splenomegaly
primary herpes infxn in adults
acute herpetic pharyngotonsillitis
Tx of Aspergillus
Allergic bronchopulm = tapered steroids, chest PT and Itraconazole; Severe sinusitis = Voriconazole + high dose steroids; aspergilloma = surgical resection if symptomatic (nothing if asyptomatic)
west nile virus caused by….
flavavirus
Tx of EBV
supportive; avoid trauma X 1 month to avoid splenic rupture
Dx of chagas
cardiac echo showing cardiomegaly with apical atrophy/aneurysm
non-painful white plaque along lateral tongue or buccal mucosa. CANNOT be scraped off.
oral hairy leukoplakia
Tx of botulism
Botulinum IG and resp support
MCC of pharyngitis
viral
MCC of encephalitis in US
HSV
Coxsackie infxn most common in which season
summer
brudzinski
neck flexion causes involuntary flexing of the hip/knee
Litseria tx
IV ampicillin + gent
Jones criteria
Rheumatic fever (GAS) - 1. Joints 2. Carditis 3. nodules 4. erythema marginatum 5. sydenham chorea
cause of rocky mountain spotted fever (RMSF)
rickettsia rickettsii
MC bacterial cause of pharyngitis
GABHS
Q fever organism
coxiella burnetti (sheep, goat, cattle feces contain the spores)
Bacillus anthracis commonly found in
animal wool/fur (sheep, goat, horse, swine)
Tx of tetanus
- intubate prn 2. tetanus IG 3. Diazepam 4. Debride 5. flagyl or Pen G prn 6. BB prn
Prophylaxis: Td vaccine q 10 years, IG if never vaccinated
Tx for candidiasis
antifungals
pathophys of trichinosis
larvae cyst grow/replicate in the duodenum/jejunum. Adults excreted in stool and larva penetrate the intestinal wall and ENCAPSULATE IN STRIATED MUSCLE TISSUE
Tx of 5th dz
supportive
Congenital Varicella syndrome (TORCH vertical transmission)
develops during 1st and 2nd trimester; Limb hypoplasia, scarring, and blindness
TX of cat scratch disease
self limiting (amox or doxy prn severe)
Tx of SARS
aggresive supportive
dx of leprosy
skin bx and AFB
Q fever sxs
ACUTE - MC pneumonia (flu-like illness). HA, fever, hepatitis.
CHRONIC - endocarditis
Tx of yersinia pestis infxn
streptomycin (aminoglycosides) + tetracyclin
(killed vaccine available)
Tetracycline used for post exposure prophylaxis
Tx of Pertussis
Erythromycin (macrolids) - does not alter course of disease, but decreases contagiousness. (alt - bactrim)
Prophylaxis for close contacts REGARDLESS of age or immunization status (macrolide).
Tdap booster for everyone!
Chicken pox begin on…
face and trunk –> extremities
Common HIV opportunistics infxns at CD4 <200
PCP, histoplasmosis
Tx of coccidiodes
Most are self limiting. CNS spread tx with Fluconazole (amp B if severe CNS dz)
Tx of syphilis
Pen G (desensatize if allergic) **Jarisch-Herscheimer reaction once tx starts (fever/chills while spirochetes are dying d/t tx)**
Tx of erysipeloid (erysipelothrix rhusiopathiae)
Pencillin G, cephalosporin or clinda
what is malaria
RBC dz caused by Plasmodium (falciparum, vivax, ovale, and malariae);
1. infects RBC 2. RBC lysis 3. cyclical fever
Rubeolla
Measles
brown watery exudates with crepitus to palpation
gas gangrene
Dx of trichinosis
Eosinophilia is hallmark
(triad: periorbital edema, myositis and eosinophilia)
Definitive dx: muscle bx
Dx of gas gangrene
air in tissues seen on x-ray
sxs of anthrax
MC - cutaneous (painless black eschar with surrounding edema and vesicles).
inhalation (flu-like sxs, mediastinum widening on CXR d/t to hemorrhagic lymphadenitis
4 C’s of Rubeola (Measles)
Cough, Coryza, Conjunctivitis and Koplik spots (small red spots in buccal mucosa with blue/white pale center)
MCC of nec fasc
GAS
violacious lesions on nose, extremities, and mucous membranes d/t proliferation of vasculature
Karposi sarcoma
Tx of chlamydia
oral azithromycin 1gm (alt doxy); oral NOT topical for neonate conjunctivitis
sxs of Creutzfeldt-jakob dz
rapid progression in dementia, gait issues, and myoclonus when startled
Dx of syphilis
RPR, if + confirm with FTA Ab testing (false positive for autoimmune conditions)
EBV infects B cells, increasing risk of…
Hodgkins Lymphoma (Reed-Sternberg/owl eyes), Non-hodgkins lymphoma (burkitts lymphoma - large jaw lesions/swelling), nasopharyngeal carcinoma (MC in asians) and oral hairy leukoplakia (in HIV pts)
Tx of nec fasc
surgical debridement and broad abx (zosyn, unasyn)
Leading cause of CHF in Latin America
Chagas dz
organism responsible for “fish tank granulomas” seen in marine workers or fisherman
mycobacterium marinum
blue, hemorrhagic bullae
nec fasc
painful genital lesion + painful inguinal LAD
Chancroid (d/t haemophilus ducreyi)
Virus that causes 5th dz
parvovirus B-19
Tx of kawasaki
IVIG + high dose ASA
Definition of acanthamoeba keratitis
minor ocular trauma, usually seen with swimming with contacts lens that become infected
Tx of CMV
gancyclovir
vesicles in different healing stages
chicken pox
Tx of RMSF
doxycycline (even for young children)
MCC of osteomylitis
Staph aureus
Parasite for chagas dz
trypanosoma cruzi
MCC of sensorineural hearing loss
congenital CMV (TORCH)
Common HIV opportunistics infxns at CD4 <50
MAC and CMV
rabid animals observed for how many days?
7-10
Tx of GAS
Penicillin G or VK (alt macrolides)
Tx of mumps
supportive, anti-inflammatories; pts are HIGHLY contagious for 9 days
Tx of chancroid
azithromycin 1g X 1 (alt ceftriaxone)
virus that causes smallpox
orthopox virus
Complications of Measles
Pneumonia
Hantavirus vector
rodents (deer mouse)
parasite for enterobiasis (pinworm)
enterobius vermicularis
small deep ulcers seen on EGD
HSV esophagitis (immunocompromised pts)
Dx of Cryptococcus
Antigen seen in CSF (India Ink stain)
outdoor activities near decaying wood soils and near waterways (great lakes)
Blastomycosis (blastomyces dermatitidis)
Tx of diphtheria
- diphtheria antitoxin + erythromycin (or penicillin) X 2 weeks
- prophylaxis tx for close contacts: erythromycin
- prevention: dtap (2,4,6 and 15 months, booster at age 4-6yo)
common diphtheria sxs
pseudomembranes, bulls neck (cervical lymphadenopathy), myocarditis (blocks/arrhythmias) and neuropathy (posterior pharynx)
EBV remains latent in the
B cells
Dx of toxoplasmosis
ring-enhancing lesions on head CT
Labs for Reactive arthritis (reiter’s syndrome)
+HLA-B27 (+chalmydia?)
5th dz complications during pregnancy (1st and 2nd trimesters)
increased fetal loss due to hydrops fetalis (CHF and edema)
Tx of babesiosis
Atovaquone and Azithromycin (OR clinda and Quinine)
Sxs of Tularemia
Fever, HA, nausea –> single papule at site of inoculation (typically the hand/arm)
Stages of lyme dz
Early - erythema migrans (central bullseye) and flu like sxs
Early disseminated - AV heart block and bell’s palsy (CN VII)
Late - migratory arthritis and encephalopathy
HHV 8
karposi sarcoma
MCC sxs of CMV (cytomegalovirus)
80-90% asymptomatic
stages of african sleeping sickness
early: painless chancre at bite site.
late: persistent HA, daytime sleepiness with nighttime insomnia
MCC of impetigo
GAS or Staph Aureus
2 main complications of GAS if untreated
Rheumatic fever and Acute post-streptococcal glomerulonephritis
Tx of chagas
nifurtimox X 3-4mo
sticato cough in neonate
chlamydia pneumonia
dx of rabies
negri bodies in brain of dead animal (hippocampus)
rashes that involve the palms/soles
coxsackie, RMSF, secondary syphilis, kawasaki, measles, TSS, Reactive arthritis and janeway lesions
Sxs of dengue fever
Biphasic fever, break bone pain, HA, flushed skin and hemorrhage (Touniquet test)
Flavivirus causes
Dengue fever, yellow fever, west nile and hep C
fifth dz, also known as…
erythema infectiosum
Reservoir for Tularemia
Rabbits (francisella tularensis)
rash presentation for RMSF
fever/chills/HA –> rash on wrist/ankles that spreads CENTRALLY. Face is spared.
Common ADEs of NRTIs
bone marrow suppression (Zidovudine), agranulocytosis, anemia, peripheral neuropathy, pancreatitis, lactic acidosis, rash (Abacavir)
Primary herpes infxn in kids
acute herpetic gingivostamatitis (vesicles in mouth, tongue and lips)
ramsay-hunt syndrome
varicella zoster oticus - otalgia, lesions on ear, auditory canal and TM, facial palsy
Dx of RMSF
clinical, do NOT delay treatment (can lead to coma, encephalopathy and organ failure)
Def of kawasaki
medium and small vessel vasculitis
Tx of impetigo
topical mupirocin
maculpapular rash develops in mono infxn if…
Amoxicillin taken (mistaken for Strep throat)
The “3 day rash”
Rubella
Leishmaniasis caused by…
female sandfly (common in mediterranean, central/south america, africa and asia)
hutchinson sign
heralding lesion on nose prior to zoster ocular involvement
Dx of aspergillus fungus
dusky, necrotic tissue on bx and seen in tissues
complications of Varicella zoster
Adults - pneumonia; immunocompromised - encephalitis
Tx of Histoplasmosis
Itraconazole (mild-mod); Amp B (severe); Prophylaxis if CD4 < 200 (Itraconazole)
Tx of pasteurella
augmentin (alt doxy)
Listeria associated with
premature labor, stillbirth and 3rd MCC of meningitis in infants <2mo
Tx of lyme dz
doxycycline, amoxicillin if <8yo X 2-3 weeks; IV ceftriaxone if severe/late stages
MC ogranism from dog/cat bite
pasteurella
The great imitator
syphilis
mad cow dz
Creutzfeldt-jakob dz
MC site of involvement for blastomycosis
Lungs (flu like sxs); MC dissemination into lungs, skin, bones (ribs/vertebral) and GU system
pinworm infection MC in which age group
school-aged kids
Grows in soil near desert/southwest/mexico regions
Coccidiodes (valley fever)
congenital syphilis causes…
hutchinson teeth (notches in teeth), saber shins, saddle-nose deformity and DEAFNESS (TORCH)
Travel to mississippi or Ohio river
Histoplasmosis capsulatum
slap cheek and lacy reticular rash
5th dz
MCC of cellulitis
Staph aureus and GAS
Tx of malaria
Chloroquine and quinidine (atovaquone with doxy if drug resistent)
MCC of septic arthritis
Staph aureus; Gonorrhea in young sexually active
Aspergillosis found in
garden and houseplant soils
Tx of coxsackie
supportive
Spirochet that causes syphilis
treponema pallidum
friable gray/white membrane on pharynx
diphtheria (corynebacterium diphtheriae)
MCC meningitis in college students
neisseria meningitidis
MCC epiglottitis
Haemophilus influenza
smallest DNA virus
parvovirus B-19
Common HIV opportunistics infxns at CD4 <500
Thrush, Kaposi Sarcoma, TB, Zoster
congenital CMV sxs
sensorineural hearing loss, blueberry muffin rash (TTP), mental retardation (MCC) and seizures
TX of brucellosis
doxy + rifampine
Reservoir for west nile
birds, MC in late summer or early fall
common NRTIs
Zidovudine, Emtricitabine, Abacavir, Lamivudine, Didanosine, Zalcitabine, Stavudine and Tenofivir
Post-exposure prophylaxis for 1st episode of rabies
HDCV (rabies vaccine) days 0, 3, 7 and 14 + rabies IG (within 6d of bite/exposure).
If immunecompromised, include day 28 in the HDCV vaccine schedule.
common valley fever sxs
fever, arthralgia, erythema nodosum/multiforme
MC sxs of bubonic plague
swollen and painful nodes (bubo) found in the groin/axilla/cervical regions
Animals that commonly transmit rabies
BATS (#1), raccoons, skunks, foxes, wolves, and DOGS
Dx of pinworm
scotch tape test
zoster ophthalmicus involved which CN
1st division of CN 5
sandpaper rash and strawberry tongue
scarlet fever (from GAS)
common infectious dz associated with arthropathy
erythema infectiosum (older adults), rubella, and coccidiodomycosis
Tx of anthrax
cipro (tx and exposure) (alt doxy +rifampin)
invasive chronic sinusitis
acute invasive aspergillius
cause of lyme dz
borrelia burgdorferi
Tx of amebiasis
Flagyl
rabies CNS phase
encephalitis, hydrophobia (painful laryngospasm with liquids), aerophobia and foaming at the mouth
cause of severe acute respiratory syndrome (SARS)
coronavirus
Whooping cough organism
Bordetella pertussis
“100 day cough”
MCC of urethritis/prostatitis/orchitis
<30 = gonorrhea
sxs of leishmaniasis
papules, plaques and ulcerations that continue to develop weeks-months after bite
childhood Rubella presentation
postaricular and occipital lymphadenopathy, maculopapular rash starting on face spreading inferiorly (3d)
Manifestations of Babesiosis
hemolytic anemia and jaundice
Can’t see, can’t pee, can’t climb a tree
Reactive arthritis
blocks release of Acetylcholinesterase –> sustained contraction
tetanus
High fever X 3-5d –> rose pink blanchable rash STARTS ON TRUNK and spreads to face
Roseola
Common NNRTIs
Efavirenz, Delaviridine, Etravirine, Nevirapine, Rilpivirine
Common PIs
AtazaNAVIR, Darunavir, Lopinavir, Nelfinavir, etc (look for ending in NAVIR)
Rubella common in which population
immigrants and non vaccinators
Varicella remains latent in the
dorsal root ganglia
stages of whooping cough
- catarrhal phase (URI sxs 1-2wks)
- paroxysmal phase (severe coughing fits with post vomiting emesis up to 6 wks)
- convalescent phase (sxs resolving, no longer contagious, lasts 1 month)
Centor criteria
Strep throat (GAS) - 1. fever 2. pharyngotonsillar exudate 3. tender anterior cervical lymphadenopathy 4. NO COUGH
dendritic lesions
keratoconjunctivitis
Common INTIs
Raltegravir and Dolutegravir
Tx of blastomycosis
Itraconazole (Amp B if severe)
complications of kawasaki
MI and coronary artery aneurysm
allergic bronchopulmonary aspergillosis PC in pts with….
asthma and CF d/t airway hypersensitivity reaction to fungus
Kawasaki dx
Warm (fever) + CREAM (4 out of 5)
C: conjunctivitis
R: rash (polymorphous)
E: extremity changes (desquamation, edema, etc)
A: Adenopathy (cervical)
M: mucous membrane involved (tongue, lips, pharnyx
phases of Hantavirus
prodromal (fever chills and severe myalgias in back and legs) and cardiopulm phase (sudden resp distress, pulm edema, CV collapse and renal failure)
Dx of SARS
CT scan (ground glass opacities or focal consolidation) and + stool test (14d)
Tx of Leprosy
Dapsone + Rifampin + clofazimine X 2-3yrs
vesicles on nail or finger
herpetic whitlow (common in dentists and kids)
large septate hyphae
Aspergillosis (Aspergillus fungus)
rhabdovirus infection of the CNS
Rabies
common phases of trichinosis
GI phase: abd pain, N/V/D.
Muscle phase: myositis and palpebral/circumorbital edema
common times to suspect pseudomonas
conjunctivitis in contact wearer, puncture wound while wearing tennis shoes, and hot tubs folliculitis
Painful parotid gland swelling
mumps
Dx of HIV
Ab testing (Elisa + within 4-12wks post-infxn); Western blot (confirmation); Viral load to check infectivity and treatment effectiveness
Fornier gangrene
penis/scrotum infection d/t trauma (MC in diabetics)
Varicella zoster virus is part of what family
Herpes (HHV 3)
Tx of Roseola
Supportive
Common ADEs of NNRTIs
TERATOGENIC, SJS, vivid dreams and CNS sxs (HA, dizzy, etc)
gram stain of yersinia pestis shows
safety pin appearance of organism (gram negative)
Common ADEs of PIs
GI, hyperlipidemia, lipodystrophy, hyperglycemia and renal stones
prion-mediated degenerative brain dz –> rapidly progressive dementia (fatal within 1 yr)
Creutzfeldt-jakob dz
Dx of CMV
owl’s eye inclusion bodies on bx of tissue
sxs of cat scratch disease
regional lymphadenopathy (MC axillary) and fever
Tx of staph aureus
nafcillin or vanco
MC opportunistic pathogen (CD4 <100 typically)
Candida Albicans
Clinical manifestations of Toxoplasmosis
- mono-like illness with cervical lymphadenopathy
- ENCEPHALITIS in immunocompromised pts (CD4 <100)
- TORCH infxn - blueberry muffin rash, hepatosplenomegaly, hearing loss and mental retardation
Tx of trichinosis
mild (self-limiting), severe (albendazole)
vector for african trypanosomiasis (african sleeping sickness)
tsetse fly (T. brucei)
Def of AIDS
+ HIV and one AIDS defining illness (or CD4 <200)
Tx of Tularemia
streptomycin (alt gentamicin or doxy)
oral hairy leukoplakia caused by…
EBV (HHV 4)
Bird (Pigeon) droppings
Cryptococcus neoformans
RMSF mc in what region
south atlantic (dog/wood tick)
What family does Roseola belong to
Herpes (HHV 6)
Dx of amebiasis
stool ova and parasites
Fungal ball on CXR
Aspergillus fungus (aspergilloma)
Dx of malaria
Giemsa stain peripheral smear (thin and thick)
HIV pts with CMV are at increased risk of what if CD4 <50
Retinitis (blindspots, unilateral), linear large SF ulcerations in esophagus, and colitis
Dx of ascariasis
eosinophilia; stool O&P
Tx for west nile
supportive
MC intestinal helminth infxn worldwide
ascariasis (d/t ascaris lumdricoides - roundworm)
MCC of fungal meningitis
Cryptococcus neoformans
Common HIV opportunistics infxns at CD4 <100
Toxoplasmosis, cryptococcus
HAART tx regimens
- 2 NRTIs + 1 NNRTI
- 2 NRTIs + 1 PI
- 2 NRTIs + 1 INSTI
Tx of neisseria meningitidis
Pen G (alt ceftriaxone); Prophylaxis for those exposed - Rifampin or Cipro
MCC of acute pancreatitis in kids
Mumps
CMV is part of what family
Herpes (HHV 5)
Dx of pertussis
Nasopharyngeal swab if in catarrhal pahse
HIGH lymphocytosis
Tx of pinworm
albendazole
Tx of Hantavirus
ICU support
sxs of brucellosis
undulant fever and anorexia
Amebiasis sxs/presentation
GI colitis, bloody diarrhea, and amebic liver abscess
dx of MAC (mycobacterium avium complex)
AFB and culture
3 phases of syphilis
1: painless genital chancre (3-4wks)
2: rash on palms/soles and condyloma lata (weeks - 6 mo)
3: gumma (soft growth with necrotic center) and argyll robertson pupil (small irregular pupil that constricts for accommodation but NOT to light); neurosyphilis (demyleniation of posterior colums –> ataxia, gait, weakness and decreased propioception); cardiovascular (aortic regurg and aneurysm)
vector for west nile
mosquitos
parasite for amebiasis
entamoeba histolytica
honey crusted
impetigo
Risk factors for H influenza
COPD, bronchiectasis, CF
Tx of ascariasis
albendazole (pyrantel if prego)
Tx of PCP
Bactrim (+prednisone prn O2 <80%)
puncture wound involving raw fish/meat/poultry
erysipeloid (erysipelothrix rhusiopathiae)
Tx of Measles (Rubeola)
Supportive and anti-inflammatory; vit A decreases morbidity and mortality; isolate for 1 week
neonate conjunctivitis causes
- gonorrhea (1-3d), 2. chlamydia (5-7d), 3. HSV (2-4wks)
Tx for human bites
augmentin (alt clindamycin)
TX of acanthamoeba keratitis
biguanides (ie. metformin), chlorahexadine (antiseptic), propamidine (SU class) and neomycin-polymyxin
sxs of measles
- Fever + URI sxs (2-3d), 2. mobiliform brick red rash on face (starting at hairline) spreading to extremities (7d)
Trichinosis caused by…
undercooked meats (PORK) - parasitic round worm infxn
MC manifestation of malaria
cyclical fever every 2-3 days (also leukopenia and thrombocytopenia)
Presentation of acanthamoeba keratitis
keratitis (especially with contacts), ocular pain, photophobia, and corneal stromal ring infiltrate on PE
Neonatal rubella (TORCH)
Teratogenic esp in 1st trimester; Congenital cataracts, PDA, sensorineural deafness, jaundice, mental retardation and blueberry muffin rash
west nile sxs
encephalitis, meningitis and flaccid paralysis –> seizures and coma
What is babesiosis?
malaria-like protozoa that attack RBC (history of tick bite from NE US area); common in long island and massachusetts
Do you have to see bite marks to start tx for rabies
NO!!!!!!!!!! once sx occur, patient rarely survive
tx of MAC
Clarithromycin + ethambutal X 12 months (+/- rifampin); prophylaxis if CD4 <50
MC opportunistic infxn in HIV pts
PCP pneumonia (CD4 typically <200)
Paramyxovirus causes…
Measles, Mumps, RSV and Parainfluenza
Yersinia pestis transmission
fleas bit rodents then bite humans