Infectious disease Flashcards
Diagnosis of systemic Aspergillosis?
Female GSD
Terreus/flavus
Galactomannan antigen sens/spec, more sens serum more spec urine
Atovaquone mechanism of action?
Structural analogue of protozoan ubiquinone (coenzyme Q), inhibits aerobic respiration electron flow
Cytauxzoon felis cytb mutations confer resistance
How to treat Cytauxzoon felis?
Atovaquone and azithromycin
60 % survive to discharge vs 26 % imidocarb diproprionate
H. capsulatum diagnosis?
Hitopath gold standard
Galactomannan antigen sens/spec
Fungal dz in brain/eye - what anti fungal?
Fluconazole
What mutation facilitates feline coronavirus systemic spread?
S gene mutation - tropism for macrophages
What tick transmits Anaplasma phagocytophilum?
Ixodes, transstadial
Morulae in neutrophils, P selectin,
Can infect cats
Morulae cannot be differentiated from E ewingii
IFAT > ELISA for ABs
New FIP treatment?
Nucleoside analogue GS-441524 = inhibit virus replication
Long term survival in some, in particular neuro but need higher dose
GC376 - 3C-like protease inhibitor