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AN SCI 375 > Infectious Disease > Flashcards

Infectious Disease Flashcards

1
Q

What is difference between virus and other pathogens?

A

Obligate requirements for intracellular growth - heavy dependence on host machinery / cell components and metabolic components.

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2
Q

What Type of virus is Rinderpest?

A

Paramyxovirus / morbillovirus/ pestes de petits ruminants

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3
Q

What does paramyxovirus / morbillovirus do in humans / animals?

A

Distemper / Measles

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4
Q

Symptoms of rinderpest?

A

Dehydrated / depressed /diarrhea / hemmorage oral lesions - gut mouth / GIT necrosis / intestinal lesions- invasion by ghengis khan

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5
Q

Extra alimentary rinderpest?

A

Immune system depression, respiratory lesions, Extra alimentary lesions

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6
Q

What is name of Glanders disease bacterium?

A

Burkholderia mallei, pseudomonas mallei

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7
Q

History Glanders?

A

WWI biological warfare
infect russian horses
WWII Japanese infected POW military

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8
Q

Glanders symptoms?

A

Oral ulcers
pyogranulomatous pneumonia
pyogranuloma in lung
Puss in bronchioles

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9
Q

Name Production Disease in pigs

A

Atrophic Rhinitis

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10
Q

What is the name of the agent involved in atrophic rhinitis?

A

Pasteurella multicoda - resides in tonsils and upper respiratory tract.

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11
Q

What does pasteurella multicoda bacterium release that causes damage?

A

dermatonecrotic factor which degrades bone

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12
Q

Is atrophic rhinitis primary / secondary pathogen?

A

Secondary is opportunistic - usually requires mucosal damage to establish itself - bordetella / ammonia etc.

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13
Q

Clinical signs of atrophic rhinitis?

A

sneezing, bloody discharge, nasal septal deviation

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14
Q

Fungi / moulds

A

Eukaryotic, primary decomposer of dead material, uptake nutrients up from the environment, reproduce sexually / asexually

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15
Q

Name a dimorphic fungi (primary pathogen)?

A

Cryptococcus neoformans - only pathogenic to mammals. C. Neofomans var gattti - appears on vancouver island

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16
Q

What does cryptococcus neoformans primarily effect?

A

Lung, CNS and Skin (dermis)

17
Q

Aspirgillus t/f is a primary pathogen?

A

FALST it is an opportunistic pathogen - occurs in comprimised animals like eating lots of grain etc. Can cause mortality same as dimorphic fungi.

18
Q

Are there vaccines / antimicrobials / immunomodulatns / quarentine / trade reestrictions / test / slaughter for fungi / molds?

A

Not really

19
Q

Parasites are eukaryotic T / f?

A

True, multicellular eukaryotes. Can infect teh ENDO (gut / lung) ecto (skin) and epiparasite (live off another parasite)

20
Q

What is an epiparasite?

A

Parasite that lives off another parasite

21
Q

How do parasites cause injury?

A

Nutrient depletion, aberrant migrations, chronic tissue injury (inflammation / allergy) persistant infestation.

22
Q

Name a parasite that east live tissue?

A

Screwworm

23
Q

When does larvae emerge after eggs deposited in screwworms? What happens after 3 days?

A

8-12 hours screwworm larvae emerge from eggs deposited and a bloody discharge is seen after 3 days. Can affect humans. Death can occur via secondary infection. Female flies attracted to wound and lay more eggs.

24
Q

Name an opportunistic pathogen?

A

Echinococcus (cystic hydatid disease)
E. Granulosus (large cysts)
E. Multiloccularis (small cysts) destroys tissue like neoplasia.

25
Q

What is the definitive host in echinococcus (cystic hydatid disease)

A

Carnivores (canine) is where the adult tapeworm releases eggs into the environment.

26
Q

Who is the dead end host in echinococcus (cystic hydatid disease)

A

Humans

27
Q

Who is the intermediate host in echinoccous disease (cystic hydatid disease)

A

Ruminants / herbivores get cysts and infective (protoscolices)

28
Q

In cystic hydatid disease (echinococus) what does the larvae form? What is the infective agent?

A

If forms hydatid cysts and PROTOSCOLICES which are infective.

29
Q

What is the name of an antiparasitic?

A

Anhelminethics. Can use immunomodulants.
Not usually a quarentine / test / slaughter issue
Can have trade restrictions for ectoparasites.

AN SCI 375 (2 decks)

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