Infectious Disease Flashcards

1
Q

What is an infectious disease?

A

Illness caused by specific infectious agent or its toxic product that results from transmission from an infected person or animal directly or indirectly

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2
Q

What are factors that affect the immune system?

A

Pregnancy

Age

Malignancy

Malnutrition

Immunosuppressive disease and treatment

Stress

Age

Obesity

Lymph trauma

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3
Q

What is the definition of a virus?

A

Subcellular organism made up only of RNA or DNA covered with proteins

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4
Q

Why are new vaccinations often needed to be created to treat viruses?

A

They have rapid replication and high mutation rates

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5
Q

Why do most viruses not require specific antiviral therapy?

A

They are self limiting

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6
Q

What are not effective for viruses?

A

Antibiotics

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7
Q

What are types of viruses?

A

Flu, herpes, hepatitis, cold

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8
Q

What is the definition of bacteria?

A

Single-celled microorganism with well defined cell walls that can grow independently on artificial media without the need for other cells

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9
Q

How is bacteria classified?

A

By shape and oxygen need

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10
Q

What percentage of bacteria makes up human pathogens?

A

38%

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11
Q

How is bacteria treated?

A

Antibiotics (may need labs to determine gram stain)

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12
Q

What are types of bacteria?

A

Streptococcus, staphylococcus, clostridium, and escherichia coli

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13
Q

What is the definition of fungi?

A

Single celled or multicellular organism

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14
Q

What are the two forms of fungi?

A

True pathogen (causes infections in healthy people)

Opportunistic pathogen (causes infection in immunocompromised people)

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15
Q

What does the common fungus yeast cause?

A

Thrust, diaper rash, and athletes foot

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16
Q

What is the treatment of fungi?

A

Antifungals or antivirals applied directly to the skin (injected in serious cases)

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17
Q

What is the definition of a parasite?

A

Organism that lives on or in a host and gets its food from or at the expense of the host

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18
Q

Where are parasites more common?

A

Rural or developing areas

19
Q

What is the mode of infections for parasites?

A

Through mouth or skin

20
Q

What are common types of parasites?

A

Pinworms and malaria from mosquitos

21
Q

What is the treatment of parasites?

A

Anti-parasitic drugs

22
Q

What is the definition of prions?

A

Infectious agent composed of protein material that can fold in multiple distinct ways leading to disease similar to viral infection

23
Q

What is the mode of transmission for prions?

A

Animal to human

24
Q

What are prions characterized by?

A

Long latent interval in the host that when reactivated causes a rapid deteriorating state

25
What is an example of prion?
Mad cow disease
26
What is the treatment for prions?
None
27
What are the types of direct contact transmission?
Person to person Bites from insects or animals Mother to unborn child
28
What are types of indirect contact transmission?
Contact with contaminated surface or through the air
29
What are microbiomes?
Microorganisms in the human gut
30
What can disorders in the microbiome cause?
Issues with the immune system
31
What is sepsis?
Body’s response to infection where the immune system triggers inflammatory responses throughout the body
32
Where does sepsis most commonly start?
Lung Urinary tract Skin GI tract
33
What are the stages of sepsis?
Sepsis Severe sepsis Septic shock
34
What are the symptoms of sepsis that when 2 out of the 3 or present it is confirmed?
Body temp > 101 or < 97 HR > 90 bpm RR > 20 breaths/min
35
What are the symptoms of severe sepsis that is confirmed if you have at least one?
Decrease in urine output Mental status change Decreased platelet count Difficulty breathing Abdominal pain
36
What is septic shock?
When all signs and symptoms of severe sepsis are present plus severe hypotension
37
What is an infection acquired in a hospital setting called?
Nosocomial infection
38
What are the most common Nosocomial infections?
E-coli Staph C-diff Pseudomonas Yeast
39
Where are the common sites of Nosocomial infection?
Urinary tract Surgical wounds Joints Lower respiratory tract
40
What are the antibiotic resistant infections?
Methicillin-resistant staphylococcus aureus (MRSA) Vancomycin resistant enterococci infection Multi-drug resistant Acinetobacter baumannii
41
What is management of MRSA?
IV vancomycin and several weeks of IV antibiotic treatment
42
What is treatment of vancomycin-resistant Enterococci infection?
Options are limited (prevention and proper utilization of antibiotics)
43
Where are Multi-drug resistant Acinetobacter baumannii usually found?
ICU environments (ventilator dependent pneumonia and bloodstream infections)
44
What is the neck check rule when exercising with infection?
Do not exercise if their are symptoms below the neck (exercise can raise fever even higher)