Infections - My Cards Flashcards
When should you refer conjunctivitis?
Eye pain
Headache or photophobia
Under 2 years
Contact lenses
Reduced visual acuity
What monitor is required for clindamycin?
Platelets - thrombocytopenia
Liver and renal function if using for over 10 days
What are the severe side effects of clindamycin?
Thrombocytopenia
C.Diff
SJS
What activity does linezolid have?
Gram positive including MRSA and VRE
No gram negative activity
What is the safety advice with linezolid? (2)
Optic neuropathy if used for more than 28 days
Blood disorders - weekly FBC
What are the contraindications for linezolid?
Adrenal tumours and thyroitoxicosis
Bipolar and schizophrenia
Uncontrolled hypotension
What are the key interactions for linezolid?
MAIOs (or used within 2 weeks)
SSRIs and TCAs - hypertensive crisis (serotonin syndrome)
What are the key side effects for trimethoprim?
Hyperkalaemia
Fungal overgrowth
SJS
Blood disorders
What is the interaction between trimethoprim and warfarin?
Increase warfarin levels - monitor INR
Why should oral preparations of vancomycin be avoided in systemic infections?
Not well absorbed (therefore oral preparations are good for C.diff
What are the key side effects for vancomycin? (5)
Red man syndrome
Thrombophlebitis- infusion site reaction
Ototoxicity
Nephrotoxicity
Thrombocytopenia
Which tetracycline has a very broad spectrum?
Minocycline
But rarely used due to irreversible pigmentation and risk of lupus-erythematosus-like syndrome
What condition are all tetracyclines contraindicated?
Myasthenia gravis
Which tetracyclines can cause oesophageal irritation?
Doxy
Mino
Tetra
Which tetracyclines interact with milk?
Demo
Oxy
Tetra