Infections Immunology RT Flashcards
Primary function of immune system?
.defend and eliminate foreign material- minimising damages
Innate immune response?
nonspecific response - not affected by prior contact
adaptive immune response
highly specific recognition and immunological memory - altered reactivity to specific antigen - more rapid response occurs with subsequent exposure.
- humoral immunity - antibodies
- cell-mediated - T cells
adaptive I r - amplify protective mechanisms - sites of antigen entry
B lymphocyte?
generates diverse antibodies
T lymphocyte
Secretes chemical messengers
also directly destroy pathogens, regulate nearly all other types of adaptive immune
Plasma cell
secretes antibodies
NK cell
destroys virally infected cells
Innate defence against entry of micro organisms?
Commensal microorganisms
Physical barrier
Secretions (physical and chemical barriers)
When barriers penetrated: mediated by:
Phagocytic cells:
1. Macrophage
2. Neutrophil
3. NK cells (cytotoxic for tumour or host cells infected with virus)
Complement system (alternative pathway)