Infections Flashcards

1
Q

What is pneumonia?

A

Infection of the alveoli and distal airways by pathogenic organisms (bacterial, viral, fungal, parasitic)

Pneumonia can be caused by various types of organisms, leading to different clinical presentations.

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2
Q

What are typical organisms that cause pneumonia?

A
  • Streptococcus Pneumoniae
  • Haemophilus Influenzae

These organisms are commonly associated with typical pneumonia presentations.

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3
Q

What are atypical organisms that can cause pneumonia?

A
  • Legionella spp.
  • Mycoplasma Pneumoniae
  • Chlamydia Pneumoniae

Atypical pneumonia often presents differently than typical pneumonia.

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4
Q

Which organisms are associated with abnormal lungs in pneumonia cases?

A
  • Moraxella Catarrhalis
  • Staphylococcus Aureus
  • Pseudomonas Aeruginosa

These pathogens are often found in patients with underlying lung conditions.

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5
Q

What are the common organisms involved in aspiration pneumonia?

A
  • Oral anaerobes
  • Enteric GNB (Klebsiella Pneumoniae, Escherichia Coli)

Aspiration pneumonia occurs when food, liquid, or vomit is inhaled into the lungs.

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6
Q

What are the key organisms in hospital-acquired pneumonia (HAP)?

A
  • Staphylococcus Aureus
  • Pseudomonas Aeruginosa
  • Enteric GNB

HAP is typically more severe and associated with resistant organisms.

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7
Q

Name some fungal organisms that can cause pneumonia.

A
  • Aspergillus spp.
  • Cryptococcus spp.
  • Pneumocystis Jirovecii
  • Histoplasmosis

Fungal pneumonia is often seen in immunocompromised patients.

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8
Q

What are some zoonotic infections that can lead to pneumonia?

A
  • Psittacosis (Chlamydia Psittaci)
  • Q Fever (Coxiella Burnetti)
  • Tularaemia (F. Tulrensis)

These infections are transmitted from animals to humans.

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9
Q

Which disease is associated with travel and can cause pneumonia?

A

Melioidosis (Burkholderia Pseudomallei)

This organism is found in specific regions and can lead to severe illness.

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10
Q

What diagnostic tools are used for pneumonia?

A
  • CXR
  • WCC, CRP
  • Lactate, UEC, LFT
  • Respiratory Viral Swabs
  • Sputum MCS, Pneumococcal & Legionella urinary antigens, Blood cultures

These tests help determine the presence and type of pneumonia.

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11
Q

What is the management for mild community-acquired pneumonia (CAP)?

A
  • Amoxicillin 1 g TDS
  • Doxycycline 100 mg BD (or both)

Treatment is usually empirical based on local guidelines.

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12
Q

What is the treatment for moderate community-acquired pneumonia (CAP)?

A
  • Benzylpenicillin 1.2 g QID
  • Doxycycline 100 mg BD

Adjustments may be made based on patient response.

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13
Q

What is the recommended treatment for severe community-acquired pneumonia (CAP)?

A
  • Ceftriaxone 1-2 g Daily
  • Azithromycin 500 mg Daily

Severe cases may require hospitalization and intravenous antibiotics.

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14
Q

What is the treatment for high dependency instability in pneumonia?

A
  • Tazocin 4.5 g TDS or QID
  • Azithromycin 500 mg Daily

High dependency patients may need more aggressive treatment.

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15
Q

What should be considered for aspiration pneumonia treatment?

A
  • Ceftriaxone 1 g Daily (consider anaerobic cover if not responding)

Coverage for anaerobes is critical in aspiration pneumonia.

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16
Q

What is the treatment for hospital-acquired pneumonia (HAP)?

A
  • Ceftriaxone 1 g Daily (unless suspecting Pseudomonas, MRSA)

Treatment may vary based on local resistance patterns.

17
Q

What is the management for anaerobic pneumonia?

A
  • Add Metronidazole 400 mg BD or swap to Tazocin 4.5 g TDS

Anaerobic coverage is essential in certain pneumonia cases.

18
Q

What are some complications of pneumonia?

A
  • Pulmonary Abscess
  • Necrotising Pneumonia
  • Parapneumonic effusion
  • Empyema

These complications can significantly worsen patient outcomes.