Infections Flashcards

1
Q

Acute Sore Throat

A

1st line: Phenoxymethylpenicillin
Penicillin allergy: Clarithromycin
Pregnant: Erythromycin

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2
Q

Influenza Treatment

A

Oseltamavir (Tamiflu) and Zanamavir (Relenza)

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3
Q

Scarlett Fever Treatment

A

1st Line: Phenyoxymethylpenicillin
(Pen V)
Penicillin allergy: Clarithromycin

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4
Q

Acute Otitis Media Treatment

A

1st line: Amoxicillin
2nd: Co-amoxiclav
Penicillin allergy: Clarithromycin
Pregnant: Erythromycin

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5
Q

(?)Acute Otitis Externa Treatment

A

1st line: Analgesia and apply localised heat.
2nd: Topical Acetic acid-2% (Ear Calm) and Topical Antibiotics/steroids
If cellulitis: Flucloxacillin

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6
Q

Sinusitis Treatment

A

1st line/Non-life-threatening: Phenoxymethylpenicillin
Penicillin allergy: Doxycycline or Clarithromycin
Pregnancy: Erythromycin
2nd line/Life Threatening: Co-amoxiclav

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7
Q

Treatment for Acute exacerbation of COPD (mild and severe)

A

Mild: Amoxicillin or Doxycycline or Clarithromycin
Severe: Co-amoxiclav or Co-trimoxazole or Levofloxacin

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8
Q

Acute exacerbation of Bronchiectasis

A

1st Line: Amoxicillin (preferred in pregnancy) or Doxycycline (not for <12 years old)
In risk of treatment failure: Co-amoxiclav, levofloxacin, ciprofloxacin.

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9
Q

Acute Cough infection treatment (LRTI)

A

Adults: Doxycycline/Amoxicillin/Clarithromycin
If pregnant: Erythromycin
Children: Amoxicillin/Clarithromycin/ Erythromycin/Doxycycline (Not <12 years old)

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10
Q

Community Acquired Pneumonia Treatment: All severities

A

Low: Amoxicillin, can also use Clarithromycin/Doxycycline (not under 12)/Erythromycin (pregnancy) CURB65- 0-1
Medium: Amoxicillin and another antibiotic (atypical pathogens suspected!) Clarithromycin and Erythromycin (pregnancy). Penicillin allergy: Doxycycline or Clarithromycin. CURB65 score -2
Severe: Co-amoxiclav + clarithromycin/Erythromycin (pregnancy). Penicillin allergy: Levofloxacin (consider patient safety issues e.g. age, kidney function etc.) CURB65 score- 3-5

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11
Q

Treatment for Community Acquired Pneumonia Treatment in children. All severities

A

Non-severe :Amoxicillin
Penicillin allergy: Clarithromycin (1month to 17 years) or Doxycycline (12 years-17 years) or erythromycin (8 years to 17 years)
Severe: Co-amoxiclav and* clarithromycin or erythromycin.
*only if atypical pathogen suspected.

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12
Q

Hospital Acquired Pneumonia treatment: all severities

A

Non-severe: Co-amoxiclav
Alternatives: Doxycycline or Cefalexin or Co-trimoxazole or Levofloxacin
(Co-trimoxazole and Levofloxacin aren’t licensed for this use)
Severe: Specialist Advice required; options include: Piperacillin with tazobactam, ceftriaxone, cefuroxime, ceftazidime, ceftazidime with avibactam, meropenem, Levofloxacin.

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13
Q

Severe HAP and suspected/confirmed MRSA INFECTION. What therapy should be added?

A

Vancomycin and Teicoplanin along with the IV antibiotics treating the HAP.
Linezolid (if vancomycin can’t be used and specialist advice only)

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14
Q

HAP Treatment (microbial) in children- All severities

A

Non-severe- Co-amoxiclav
Penicillin allergy: Clarithromycin
Severe- IV antibiotics by specialist options include: Piperacillin with Tazobactam, Ceftazidime, Ceftriaxone.

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15
Q

Urinary tract infection treatment in women

A

1st line: Nitrofuratoin (if eGFR >45) or trimethoprim.
2nd: Nitrofuratoin, pivmecillinam or fosfomycin (3 days)
Pregnancy: Nitrofuratoin (avoid at term due to risk of neonatal haemolysis)
2nd line: amoxicillin and cefalexin for 7 days.

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16
Q

Urinary Tract Infection treatments for Men

A

1st line: Trimethoprim
2nd line: Nitrofuratoin for 7 days

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17
Q

Urinary tract infections for children over 3 months

A

1st line: Nitrofuratoin, Trimethoprim
2nd line: Nitrofuratoin, amoxicillin, cefalexin

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18
Q

Acute Prostatis Treatment

A

1st line: Ciprofloxacin, ofloxacin, trimethoprim
2nd line: Levofloxacin, Co-trimoxazole

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19
Q

Acute Pyelonephritis (Upper UTI)

A

1st line in Women: cefalexin, trimethoprim, ciprofloxacin, Co-amoxiclav
1st line in Men: IV Antibiotics (specialist)
Pregnancy: Cefalexin
Children over 3 months: Co-amoxiclav

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20
Q

Prophylactic Recurrent UTI Treatment

A

Prophylaxis:
1st line: Nitrofuratoin or Trimethoprim
2nd line: amoxicillin or cefalexin

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21
Q

Catheter associated UTI

A

1st line with no upper UTI symptoms: Nitrofuratoin, Trimethoprim, amoxicillin.
2nd line with no upper UTI symptoms:
Cefalexin, Co-amoxiclav, trimethoprim, ciprofloxacin.
Pregnancy: Cefalexin
Children over 3 months: Trimethoprim, amoxicillin, Co-amoxiclav, Cefalexin

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22
Q

Bacterial Meningococcal Meningitis treatment

A

IV/IM Benzylpenicillin, cefotaxime, ceftriaxone.
Penicillin allergy: Chloramphenicol

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23
Q

Oral candidiasis treatment

A

Miconazole gel if not tolerated use Nystatin oral solution.
Fluconazole can be used if severe.

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24
Q

Infectious diarrhoea treatment

A

If campylobacter suspected: clarithromycin
If giardia suspected: tinidazole

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25
Traveller’s Diarrhoea treatment
Azithromycin Prophylaxis: Bismuth subsalicylate
26
Threadworms treatment
Adults and children >6 months: Mebendazole Children <6 months and pregnancy: only hygiene measures.
27
C. Difficile infection treatment
1st line: Vancomycin 2nd line: Fidaxomicin Relapse infection within 12 weeks: Fidaxomicin Relapse infection after 12 weeks: Vancomycin (and Fidaxomicin if it’s severe)
28
Helicobacter Pylori treatment
Triple therapy: 2 antibiotics and a PPI Amoxicillin, clarithromycin and metronidazole are normally considered first line.
29
H. Pylori treatment 2nd line
PML -(PPI +metronidazole+levofloxacin) To be used if levo/clarithromycin is unsuccessful: PBMT -(PPI + Bismuth+ metronidazole+tetracycline)
30
Acute diverticulitis Treatment
1st line: Co-amoxiclav 2nd line/penicillin allergy: Cefalexin and metronidazole, OR trimethoprim and metronidazole, OR ciprofloxacin and metronidazole.
31
Conjunctivitis treatment
Chloramphenicol
32
Chlamydia Trachomata/Urethritis Treatment
1st line: Doxycycline 2nd line/allergy/breastfeeding/intolerance: Azithromycin
33
Epididymitis gram negative bacteria
Doxycycline or ofloxacin or ciprofloxacin
34
Vaginal Candidiasis Treatment
Clotrimazole or fenticonazole or oral fluconazole. If recurrent, then oral fluconazole 150mg every 72 hours then 150mg once weekly
35
Bacterial Vaginitis
Oral or topical Metronidazole gel Or clindamycin 2% cream
36
Genital Herpes Treatment
Oral Aciclovir or Valaciclovir or famciclovir
37
Gonorrhoea treatment (Susceptibility known and unknown)
Known: Ciprofloxacin 500mg single oral dose Unknown/Pregnancy : Ceftriaxone 1g IM Alternatively: Azithromycin 2g single dose oral + (gentamicin 240mg IM/cefixime 400mg oral)
38
Trichomoniasis Treatment
Metronidazole or Clotrimazole
39
Pelvic Inflammatory Disease Treatment
1st line: Ceftriaxone+metronidazole+ doxycycline 2nd line: (metronidazole+ofloxacin) or moxifoxacin alone
40
Cold sores Treatment
Aciclovir 400mg BD
41
Eczema bacterial infection treatment
Topical antibiotics 1st line: Fusidic acid 2% Oral antibiotics 1st line: Flucloxacillin Penicillin allergy: Clarithromycin or Erythromycin (pregnant)
42
Impetigo Treatment
Topical antiseptic: Hydrogen peroxide 1% Topical antibiotics: 1st line: fusidic acid 2% Resistance option: mupirocin 2% Oral antibiotics: Flucloxacillin (clarithromycin or erythromycin in pregnancy)
43
Mastitis treatment
1st line: Flucloxacillin Penicillin allergy/pregnancy: Clarithromycin or Erythromycin (in pregnancy)
44
Leg Ulcer infection treatment
1st line: Flucloxacillin Unsuitable/pregnancy: doxycycline or clarithromycin, erythromycin (in pregnancy) 2nd line: Co-amoxiclav or Co-trimoxazole (penicillin allergy)
45
Cellulitis and/or erysipelas treatment (away from face)
1st line: Flucloxacillin Penicillin allergy/unsuitable: clarithromycin, Co-amoxiclav, doxycycline (adults only) Pregnancy: Erythromycin
46
Cellulitis and/or erysipelas treatment (near eyes and nose)
1st line: Co-amoxiclav Penicillin allergy: clarithromycin and metronidazole (only add metronidazole in children if anaerobes are present)
47
Mild Diabetic foot infection treatment
1st line: Flucloxacillin Penicillin allergy: Clarithromycin or Doxycycline Pregnancy: Erythromycin
48
Mild Acne Vulgaris treatment
Benzoyl peroxide or topical clindamycin (not in under 12)
49
Scabies treatment
Permethrin Penicillin allergy: malathion (6 months over)
50
Insect bite treatment
Chlorophenamine
51
Human animal Bite treatment
1st line: Co-amoxiclav Penicillin allergy: doxycycline and metronidazole
52
Dermatophyte skin infection treatment
Topical terbafine/imidazole
53
Dermatophyte nail treatment
1st line: Terbafine 2nd line: Itraconazole
54
Varicella Zoster/Chickenpox/Shingles treatment
1st line: Aciclovir 2nd line: famiciclovir or valaciclovir
55
Conjunctivitis treatment
1st line: Bath/clean eyelid with cotton wool dipped in sterile saline or boiled cooled water to remove crusting 2nd line: Chloramphenicol eye drops or ointment 3rd line: fusidic acid 1%
56
Blepharitis treatment
1st line: Lid Hygiene for symptoms 2nd line: Topical Chloramphenicol 3rd line: Oral oxytetracycline or doxycycline
57
Mucosal ulceration and inflammation treatment (simple gingivitis)
Chlorhexidine 0.1-0.12% or Hydrogen peroxide 6%
58
Acute necrotising ulcerative gingivitis treatment
Chlorhexidine 0.1-0.12% or hydrogen peroxide or metronidazole
59
Pericoronitis treatment
Metronidazole/amoxicillin+ Chlorhexidine/hydrogen peroxide
60
Dental abscess treatment
Amoxicillin or Phenoxymethylpenicillin Penicillin allergy: metronidazole or clarithromycin
61
Osteomyelitis treatment for 6 weeks
Flucloxacillin Penicillin allergy: Clindamycin *consider adding fusidic acid and rifampicin for initial 2 weeks*
62
Epiglottis treatment
1st line: Cefotaxime or ceftriaxone Penicillin allergy: Chloramphenicol
63
Syphillis treatment
Benzylpenicillin or procaine penicillin
64
Treating Septicaemia
Anti-pseudomonal beta lactam e.g. Piperacillin with tazobactam, Ticarcillin with clavulanic acid, or broad spec cephalosporin (Cefuroxime). Add metronidazole if anaerobic infection
65
Initial Blind Endocarditis treatment
1st line: Amoxicillin (maybe add low dose gentamicin) Penicillin allergy/MRSA suspected: Vancomycin and low dose gentamicin If severe sepsis with risk factors for gram negative: Vancomycin +Meropenem
66
Prosthetic valve endocarditis
Vancomycin+ Rifampicin+ low-dose gentamicin
67
Staphylococcal endocarditis treatment
1st line: Flucloxacillin for 4 weeks Penicillin allergy/MRSA: Vancomycin+ rifampicin for 4 weeks ( 6 weeks if secondary lung abscess or osteomyelitis is also there)
68
Staphylococcal endocarditis with prosthetic valve treatment
1st line: Flucloxacillin+rifampicin+low dose gentamicin Penicillin allergy/MRSA: Vancomycin+ rifampicin+low dose gentamicin Both plans for 6 weeks
69
Fully sensitive streptococcal endocarditis treatment
1st line: Benzylpenicillin Penicillin allergy: Vancomycin (or teicoplanin) + low dose gentamicin Duration: 4-6 weeks (Stop gentamicin after 2 weeks)
70
Less-sensitive streptococcal endocarditis treatment
Benzylpenicillin+ low dose gentamicin
71
Enterococcal endocarditis treatment
1st line: Amoxicillin or Benzylpenicillin +low dose gentamicin Penicillin allergy/resistance: Vancomycin (or teicoplanin)+ low dose gentamicin
72
HACEK Endocarditis treatment
1st line: Amoxicillin +low dose gentamicin Penicillin allergy/resistance: Ceftriaxone (or cefotaxime) + low dose gentamicin