Infections Flashcards

1
Q

Acute Sore Throat

A

1st line: Phenoxymethylpenicillin
Penicillin allergy: Clarithromycin
Pregnant: Erythromycin

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2
Q

Influenza Treatment

A

Oseltamavir (Tamiflu) and Zanamavir (Relenza)

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3
Q

Scarlett Fever Treatment

A

1st Line: Phenyoxymethylpenicillin
(Pen V)
Penicillin allergy: Clarithromycin

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4
Q

Acute Otitis Media Treatment

A

1st line: Amoxicillin
2nd: Co-amoxiclav
Penicillin allergy: Clarithromycin
Pregnant: Erythromycin

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5
Q

(?)Acute Otitis Externa Treatment

A

1st line: Analgesia and apply localised heat.
2nd: Topical Acetic acid-2% (Ear Calm) and Topical Antibiotics/steroids
If cellulitis: Flucloxacillin

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6
Q

Sinusitis Treatment

A

1st line/Non-life-threatening: Phenoxymethylpenicillin
Penicillin allergy: Doxycycline or Clarithromycin
Pregnancy: Erythromycin
2nd line/Life Threatening: Co-amoxiclav

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7
Q

Treatment for Acute exacerbation of COPD (mild and severe)

A

Mild: Amoxicillin or Doxycycline or Clarithromycin
Severe: Co-amoxiclav or Co-trimoxazole or Levofloxacin

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8
Q

Acute exacerbation of Bronchiectasis

A

1st Line: Amoxicillin (preferred in pregnancy) or Doxycycline (not for <12 years old)
In risk of treatment failure: Co-amoxiclav, levofloxacin, ciprofloxacin.

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9
Q

Acute Cough infection treatment (LRTI)

A

Adults: Doxycycline/Amoxicillin/Clarithromycin
If pregnant: Erythromycin
Children: Amoxicillin/Clarithromycin/ Erythromycin/Doxycycline (Not <12 years old)

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10
Q

Community Acquired Pneumonia Treatment: All severities

A

Low: Amoxicillin, can also use Clarithromycin/Doxycycline (not under 12)/Erythromycin (pregnancy) CURB65- 0-1
Medium: Amoxicillin and another antibiotic (atypical pathogens suspected!) Clarithromycin and Erythromycin (pregnancy). Penicillin allergy: Doxycycline or Clarithromycin. CURB65 score -2
Severe: Co-amoxiclav + clarithromycin/Erythromycin (pregnancy). Penicillin allergy: Levofloxacin (consider patient safety issues e.g. age, kidney function etc.) CURB65 score- 3-5

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11
Q

Treatment for Community Acquired Pneumonia Treatment in children. All severities

A

Non-severe :Amoxicillin
Penicillin allergy: Clarithromycin (1month to 17 years) or Doxycycline (12 years-17 years) or erythromycin (8 years to 17 years)
Severe: Co-amoxiclav and* clarithromycin or erythromycin.
*only if atypical pathogen suspected.

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12
Q

Hospital Acquired Pneumonia treatment: all severities

A

Non-severe: Co-amoxiclav
Alternatives: Doxycycline or Cefalexin or Co-trimoxazole or Levofloxacin
(Co-trimoxazole and Levofloxacin aren’t licensed for this use)
Severe: Specialist Advice required; options include: Piperacillin with tazobactam, ceftriaxone, cefuroxime, ceftazidime, ceftazidime with avibactam, meropenem, Levofloxacin.

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13
Q

Severe HAP and suspected/confirmed MRSA INFECTION. What therapy should be added?

A

Vancomycin and Teicoplanin along with the IV antibiotics treating the HAP.
Linezolid (if vancomycin can’t be used and specialist advice only)

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14
Q

HAP Treatment (microbial) in children- All severities

A

Non-severe- Co-amoxiclav
Penicillin allergy: Clarithromycin
Severe- IV antibiotics by specialist options include: Piperacillin with Tazobactam, Ceftazidime, Ceftriaxone.

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15
Q

Urinary tract infection treatment in women

A

1st line: Nitrofuratoin (if eGFR >45) or trimethoprim.
2nd: Nitrofuratoin, pivmecillinam or fosfomycin (3 days)
Pregnancy: Nitrofuratoin (avoid at term due to risk of neonatal haemolysis)
2nd line: amoxicillin and cefalexin for 7 days.

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16
Q

Urinary Tract Infection treatments for Men

A

1st line: Trimethoprim
2nd line: Nitrofuratoin for 7 days

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17
Q

Urinary tract infections for children over 3 months

A

1st line: Nitrofuratoin, Trimethoprim
2nd line: Nitrofuratoin, amoxicillin, cefalexin

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18
Q

Acute Prostatis Treatment

A

1st line: Ciprofloxacin, ofloxacin, trimethoprim
2nd line: Levofloxacin, Co-trimoxazole

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19
Q

Acute Pyelonephritis (Upper UTI)

A

1st line in Women: cefalexin, trimethoprim, ciprofloxacin, Co-amoxiclav
1st line in Men: IV Antibiotics (specialist)
Pregnancy: Cefalexin
Children over 3 months: Co-amoxiclav

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20
Q

Prophylactic Recurrent UTI Treatment

A

Prophylaxis:
1st line: Nitrofuratoin or Trimethoprim
2nd line: amoxicillin or cefalexin

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21
Q

Catheter associated UTI

A

1st line with no upper UTI symptoms: Nitrofuratoin, Trimethoprim, amoxicillin.
2nd line with no upper UTI symptoms:
Cefalexin, Co-amoxiclav, trimethoprim, ciprofloxacin.
Pregnancy: Cefalexin
Children over 3 months: Trimethoprim, amoxicillin, Co-amoxiclav, Cefalexin

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22
Q

Bacterial Meningococcal Meningitis treatment

A

IV/IM Benzylpenicillin, cefotaxime, ceftriaxone.
Penicillin allergy: Chloramphenicol

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23
Q

Oral candidiasis treatment

A

Miconazole gel if not tolerated use Nystatin oral solution.
Fluconazole can be used if severe.

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24
Q

Infectious diarrhoea treatment

A

If campylobacter suspected: clarithromycin
If giardia suspected: tinidazole

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25
Q

Traveller’s Diarrhoea treatment

A

Azithromycin
Prophylaxis: Bismuth subsalicylate

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26
Q

Threadworms treatment

A

Adults and children >6 months: Mebendazole
Children <6 months and pregnancy: only hygiene measures.

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27
Q

C. Difficile infection treatment

A

1st line: Vancomycin
2nd line: Fidaxomicin
Relapse infection within 12 weeks: Fidaxomicin
Relapse infection after 12 weeks: Vancomycin (and Fidaxomicin if it’s severe)

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28
Q

Helicobacter Pylori treatment

A

Triple therapy: 2 antibiotics and a PPI
Amoxicillin, clarithromycin and metronidazole are normally considered first line.

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29
Q

H. Pylori treatment 2nd line

A

PML -(PPI +metronidazole+levofloxacin)

To be used if levo/clarithromycin is unsuccessful: PBMT -(PPI + Bismuth+ metronidazole+tetracycline)

30
Q

Acute diverticulitis Treatment

A

1st line: Co-amoxiclav
2nd line/penicillin allergy:
Cefalexin and metronidazole, OR trimethoprim and metronidazole, OR ciprofloxacin and metronidazole.

31
Q

Conjunctivitis treatment

A

Chloramphenicol

32
Q

Chlamydia Trachomata/Urethritis Treatment

A

1st line: Doxycycline
2nd line/allergy/breastfeeding/intolerance: Azithromycin

33
Q

Epididymitis gram negative bacteria

A

Doxycycline or ofloxacin or ciprofloxacin

34
Q

Vaginal Candidiasis Treatment

A

Clotrimazole or fenticonazole or oral fluconazole.
If recurrent, then oral fluconazole 150mg every 72 hours then 150mg once weekly

35
Q

Bacterial Vaginitis

A

Oral or topical Metronidazole gel
Or clindamycin 2% cream

36
Q

Genital Herpes Treatment

A

Oral Aciclovir or

Valaciclovir or famciclovir

37
Q

Gonorrhoea treatment (Susceptibility known and unknown)

A

Known: Ciprofloxacin 500mg single oral dose
Unknown/Pregnancy : Ceftriaxone 1g IM
Alternatively: Azithromycin 2g single dose oral + (gentamicin 240mg IM/cefixime 400mg oral)

38
Q

Trichomoniasis Treatment

A

Metronidazole or Clotrimazole

39
Q

Pelvic Inflammatory Disease Treatment

A

1st line: Ceftriaxone+metronidazole+ doxycycline
2nd line: (metronidazole+ofloxacin) or moxifoxacin alone

40
Q

Cold sores Treatment

A

Aciclovir 400mg BD

41
Q

Eczema bacterial infection treatment

A

Topical antibiotics
1st line: Fusidic acid 2%
Oral antibiotics
1st line: Flucloxacillin
Penicillin allergy: Clarithromycin or Erythromycin (pregnant)

42
Q

Impetigo Treatment

A

Topical antiseptic: Hydrogen peroxide 1%
Topical antibiotics:
1st line: fusidic acid 2%
Resistance option: mupirocin 2%
Oral antibiotics:
Flucloxacillin (clarithromycin or erythromycin in pregnancy)

43
Q

Mastitis treatment

A

1st line: Flucloxacillin
Penicillin allergy/pregnancy: Clarithromycin or Erythromycin (in pregnancy)

44
Q

Leg Ulcer infection treatment

A

1st line: Flucloxacillin
Unsuitable/pregnancy: doxycycline or clarithromycin, erythromycin (in pregnancy)
2nd line: Co-amoxiclav or
Co-trimoxazole (penicillin allergy)

45
Q

Cellulitis and/or erysipelas treatment (away from face)

A

1st line: Flucloxacillin
Penicillin allergy/unsuitable: clarithromycin, Co-amoxiclav, doxycycline (adults only)
Pregnancy: Erythromycin

46
Q

Cellulitis and/or erysipelas treatment (near eyes and nose)

A

1st line: Co-amoxiclav
Penicillin allergy: clarithromycin and metronidazole (only add metronidazole in children if anaerobes are present)

47
Q

Mild Diabetic foot infection treatment

A

1st line: Flucloxacillin
Penicillin allergy: Clarithromycin or Doxycycline
Pregnancy: Erythromycin

48
Q

Mild Acne Vulgaris treatment

A

Benzoyl peroxide or topical clindamycin (not in under 12)

49
Q

Scabies treatment

A

Permethrin
Penicillin allergy: malathion (6 months over)

50
Q

Insect bite treatment

A

Chlorophenamine

51
Q

Human animal Bite treatment

A

1st line: Co-amoxiclav
Penicillin allergy: doxycycline and metronidazole

52
Q

Dermatophyte skin infection treatment

A

Topical terbafine/imidazole

53
Q

Dermatophyte nail treatment

A

1st line: Terbafine
2nd line: Itraconazole

54
Q

Varicella Zoster/Chickenpox/Shingles treatment

A

1st line: Aciclovir
2nd line: famiciclovir or valaciclovir

55
Q

Conjunctivitis treatment

A

1st line: Bath/clean eyelid with cotton wool dipped in sterile saline or boiled cooled water to remove crusting
2nd line: Chloramphenicol eye drops or ointment
3rd line: fusidic acid 1%

56
Q

Blepharitis treatment

A

1st line: Lid Hygiene for symptoms
2nd line: Topical Chloramphenicol
3rd line: Oral oxytetracycline or doxycycline

57
Q

Mucosal ulceration and inflammation treatment (simple gingivitis)

A

Chlorhexidine 0.1-0.12% or
Hydrogen peroxide 6%

58
Q

Acute necrotising ulcerative gingivitis treatment

A

Chlorhexidine 0.1-0.12% or hydrogen peroxide or metronidazole

59
Q

Pericoronitis treatment

A

Metronidazole/amoxicillin+ Chlorhexidine/hydrogen peroxide

60
Q

Dental abscess treatment

A

Amoxicillin or Phenoxymethylpenicillin
Penicillin allergy: metronidazole or clarithromycin

61
Q

Osteomyelitis treatment for 6 weeks

A

Flucloxacillin
Penicillin allergy: Clindamycin
consider adding fusidic acid and rifampicin for initial 2 weeks

62
Q

Epiglottis treatment

A

1st line: Cefotaxime or ceftriaxone
Penicillin allergy: Chloramphenicol

63
Q

Syphillis treatment

A

Benzylpenicillin or procaine penicillin

64
Q

Treating Septicaemia

A

Anti-pseudomonal beta lactam e.g. Piperacillin with tazobactam, Ticarcillin with clavulanic acid, or broad spec cephalosporin (Cefuroxime).

Add metronidazole if anaerobic infection

65
Q

Initial Blind Endocarditis treatment

A

1st line: Amoxicillin (maybe add low dose gentamicin)
Penicillin allergy/MRSA suspected: Vancomycin and low dose gentamicin

If severe sepsis with risk factors for gram negative: Vancomycin +Meropenem

66
Q

Prosthetic valve endocarditis

A

Vancomycin+ Rifampicin+ low-dose gentamicin

67
Q

Staphylococcal endocarditis treatment

A

1st line: Flucloxacillin for 4 weeks
Penicillin allergy/MRSA: Vancomycin+ rifampicin for 4 weeks

( 6 weeks if secondary lung abscess or osteomyelitis is also there)

68
Q

Staphylococcal endocarditis with prosthetic valve treatment

A

1st line: Flucloxacillin+rifampicin+low dose gentamicin
Penicillin allergy/MRSA: Vancomycin+ rifampicin+low dose gentamicin

Both plans for 6 weeks

69
Q

Fully sensitive streptococcal endocarditis treatment

A

1st line: Benzylpenicillin
Penicillin allergy: Vancomycin (or teicoplanin) + low dose gentamicin

Duration: 4-6 weeks (Stop gentamicin after 2 weeks)

70
Q

Less-sensitive streptococcal endocarditis treatment

A

Benzylpenicillin+ low dose gentamicin

71
Q

Enterococcal endocarditis treatment

A

1st line: Amoxicillin or Benzylpenicillin +low dose gentamicin
Penicillin allergy/resistance: Vancomycin (or teicoplanin)+ low dose gentamicin

72
Q

HACEK Endocarditis treatment

A

1st line: Amoxicillin +low dose gentamicin
Penicillin allergy/resistance: Ceftriaxone (or cefotaxime) + low dose gentamicin