Infection Prevention & Control Flashcards

1
Q

What are the 6 steps in the chain of infection necessary to cause disease?

A

1) Pathogenic organism - of sufficient virulence and in adequate numbers to cause disease
2) Reservoir or source that allows the organism to survive and multiply
3) Mode of exit from the source
4) Mode of transmission from the source to the host
5) Portal of entry through which the pathogen can enter the host
6) Susceptible (ie. non-immune) host

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2
Q

Infection prevention and control refers to activities undertake with the aim of breaking the chain of infection, give 5 possible chain interventions?

A

1) Eliminate pathogenic organism
2) Remove source/reservoir
3) Minimise transmission
4) Eliminate exit and entry
5) Reduce susceptibility to infection

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3
Q

Give 4 examples of how pathogenic organisms can be eliminated?

A

1) Environmental cleaning and decontamination: H2O2 room decontamination, spillage management, laundry
2) Equipment decontamination: sterilisation, disinfection
3) Antisepsis: Surgical skin prep, MRSA decolonisation
4) Antibiotic prophylaxis: perioperative, post-exposure

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4
Q

Give 2 ways in which a source or reservoir can be removed?

A

1) Hand hygiene

2) Environmental cleaning and decontamination

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5
Q

Give 5 ways in which transmission can be minimised?

A

1) Hand hygiene
2) Personal protective equipment PPE
3) Equipment decontamination: Surgical instruments, stethoscopes, BP monitors, USS probes
4) Source and protective isolation
5) Use of disposable equipment: syringes, needles

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6
Q

Give 5 ways in which infection prevention and control can eliminate entry and exit?

A

1) Antisepsis: surgical skin prep
2) Asepsis: insertion and management of invasive devices
3) Air handling: air filtration and laminar flow, positive pressure ventilated lobby rooms
4) Sharps management
5) Patient management: minimise use an duration of invasive devices

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7
Q

Give 2 ways in which infection prevention and control reduces susceptibility to infection?

A

1) Ab stewardship - start smart then focus - reduce susceptibility to c.diff infection, reduce change of colonisation with multi-resistant organisms
2) Immunisation

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8
Q

What is meant by surveillance in infection prevention and control?

A

Process of gathering information to ensure that disease outbreaks are pre-empted or identified early
Have alert organisms (organisms with the propensity to cause outbreaks) and alert conditions (conditions caused by such organisms)

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9
Q

How is surveillance carried out in infection prevention an control?

A

Hospitals - IPC team, passive surveillance: clinical reporting and laboratory records, active surveillance: seeking out trouble e.g. surgical site infection surveillance programmes
Community - legislation on reportable/notifiable diseases

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10
Q

What is meant by the process of sterilisation?

A

1) Complete killing or removal of all types of micro-organisms - bacteria both vegetative and spores, viruses, fungi and mycobacteria

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11
Q

Which 2 common bacteria survive as spores?

A

1) Clostridium tetani

2) C.difficile

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12
Q

What is meant by vegetative bacteria?

A

Bacteria endowed with the power or faculty of growth

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13
Q

Give the 4 main methods of sterilisation?

A

1) Heat - moist, dry
2) Chemical - gas, liquid
3) Filtration
4) Ionising radiation - used for single use disposable equipment

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14
Q

Give the 2 methods of sterilisation by heat?

A

1) Moist heat - autoclave - delivery of steam under high pressure, specific pressure and temperature cycles
2) Dry heat - oven - controlled temperature cycles, 160 degrees for 2 hours or 170 degrees for 1 hr

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15
Q

What is meant by disinfection?

A

Removal or destruction of sufficient numbers of potentially harmful micro-organisms to make an item safe to use

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16
Q

What is meant by antisepsis?

A

Antisepsis is disinfection applied to damaged skin or living tissues - requires a disinfectant with minimal toxicity

17
Q

In which way is disinfection almost always achieved?

A

By use of chemical disinfectants

18
Q

What 4 considerations need to be made when choosing a chemical disinfectant?

A

1) Effects on micro-organisms - antimicrobial spectrum, sporicidality
2) Chemical properties - shelf life, in-use concentration, compatibility with other chemicals
3) Physical effects - corrosiveness
4) Harmful effects - irritant potential, toxicity

19
Q

What 3 factors need to be considered when choosing the method of infection control of items?

A

1) Risk of infection - high, intermediate, low
2) Physical properties - item, packaging material
3) Decontamination level - sterilisation, disinfection (antisepsis), cleaning, disposal

20
Q

Which is the least hazardous method of cleaning and is used where possible?

A

Heat

21
Q

Chemical disinfection is largely limited to which 3 situations?

A

1) Environmental decontamination - surfaces, spills etc.
2) Antisepsis
3) Heat-sensitive items

22
Q

In surgical instrument reprocessing what is the risk of infection, physical properties to consider and decontamination level and method?

A

Risk of infection: high
Physical properties: metal construction, paper/cloth packaging
Decontamination level: sterilisation
Decontamination method: moist heat

23
Q

What is the risk of infection, physical properties and decontamination level and method of a flexible endoscope?

A

Risk of infection: high
Physical properties: metal/plastic construction, fragile, sensitive parts
Decontamination level: high level disinfection
Decontamination method: chemical (several alternative agents, delivered via ‘washer-disinfector’)

24
Q

What is the risk of infection, physical properties and decontamination level and method of a syringe needle?

A

Risk of infection: high
Physical properties: Plastic/metal construction, paper packaging
Decontamination level: sterilisation
Decontamination method: gamma-irradiation pre-use, disposal after use

25
Q

What are the physical properties, decontamination levels and decontamination method of a central venous catheter insertion site?

A

Physical properties: living tissue
Decontamination level: disinfection (antisepsis)
Decontamination method: chemical (2% chlorhexidane in 70% isopropyl alcohol)

26
Q

What are the physical properties and decontamination level and decontamination method or a surgeon’s hands?

A

Physical properties: living tissue
Decontamination level: washing
Decontamination method: surgical scrub