Infection, Immunity + Pathogenesis Flashcards

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1
Q

How does a sneeze transmit disease?

A

As we sneeze we produce a large number of aerosols - within these are huge numbers of infectious particles!

A single sneeze can release 100 thousand infectious viral particles.

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2
Q

What is correct about cytotoxic T lymphocytes?

A

Cytotoxic T Lymphocytes have the CDS molecule!

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3
Q

Chancroid is caused by…

A

Haemophilus ducrevi

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4
Q

The most common outcome of infection with Mycobacterium tuberculosis is…

A

Latent tuberculosis

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5
Q

Zoonoses are infections that…

A

Occur in animals and humans

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6
Q

Replication of Plasmodium in the liver cell is known as…

A

The exoerythrocytic cycle

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7
Q

The common myeloid progenitor gives rise to…

A

Monocytes

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8
Q

Virulence factors may be…

A

Toxins
Leukocidins
Proteases
Flagella

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9
Q

What causes a discharge from the GU tract?

A

Gonorrhoea

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10
Q

Which infectious agent has a stage known as an elementary body?

A

Chlamydia trachomatis

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11
Q

Non-lethal multiplication of Yersinia pestis in FLEAS and wild RODENTS is known as the…

A

Sylvatic cycle

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12
Q

Thalassemias gives resistance to…

A

Malaria

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13
Q

What is NOT part of adaptive immunity?

A

Skin

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14
Q

People who are at most risk of tuberculosis in the UK are NOT…

A

Those who are sexually promiscuous people

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15
Q

Rabies is transmitted by…

A

Direct transmission

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16
Q

What 2 statements about phagocytes are INCORRECT?

A

Neutrophil phagocytes are derived from monocytes

The phagosome recognises bacteria using the T-cell receptor

17
Q

What 2 activities can cytotoxic T cells perform?

A

Release Perforin to create pores in the target cell membrane

Release Granzyme to induce Apoptosis of an infected cell

18
Q

The common cold can be caused by which 2 organisms?

A

Rhinovirus

Coronavirus

19
Q

What2 statements about Chlamydia are INCORRECT?

A

Asymptomatic chlamydia is NOT transmissible

Vaccination against chlamydia IS effective

20
Q

What 2 statements about immune response cells are correct?

A

B cells produce antibodies

Natural killer cells are derived from the Lymphoid Progenitor Cell

21
Q

Which molecules allow sub typing of Influenza A?

A

Hemagglutinin + Neuraminidase

22
Q

What neurotransmitter is blocked by the Tetanus toxin?

A

Glycine!

23
Q

What molecule would you use to treat Gonorrhoea?

A

Ceftriaxone