Infection Control Flashcards
Causes of surgical/traumatic wound HAIs?
- Improper skin preparation
- failure to cleanse skin properly
- failure to use aseptic technique for dressings
- use of contaminated antiseptics
- improper hand hygiene
Causes of urinary tract HAIs?
- Unsterile catheterization
- inadequate catheter monitoring, tubing obstructions
- improper specimen collection
- urine reflux into bladder
- improper hand hygiene
Causes of respiratory tract HAIs?
- Contaminated respiratory equipment
- failure to use aseptic technique during suctioning
- improper secretion disposal
- improper hand hygiene
Causes of bloodstream HAIs?
- Contaminated IV tubing/needles
- medication additives to IV fluid
- connecting tubes to IV system
- improper IV insertion/care
- failure to change IV site with inflammation
- improper blood product administration
- improper dialysis catheter care
- improper hand hygiene
What is immune senescence?
An age-related decline in immune system function that increases susceptibility to infection and weakens the overall immune response.
How do age-related changes affect response to infection in older adults?
They can result in atypical signs and symptoms of infection.
What factors increase older adults’ exposure to pathogens?
- Chronic diseases
- Hospitalization
- Institutionalization
Risk factors for infections in older patients include
- Poor nutrition
- Unintentional weight loss
- Low serum albumin levels.
What infections have increased risk and mortality in older adults due to age-related immune changes?
Pneumonia and influenza.
Older adults present with altered responses to infections how?
With altered, atypical signs and symptoms such as confusion.
How does susceptibility to infection change with age?
Susceptibility changes throughout the lifespan. Infants have immature defenses, while older adults experience immune senescence increasing susceptibility.
What protects breastfed infants from infection?
Breastfed infants receive antibodies from the mother’s breast milk, providing greater immunity than formula-fed infants.
What infections are children still susceptible to as their immune system matures?
Children remain susceptible to common cold viruses, intestinal infections, and vaccine-preventable diseases like mumps and measles if not vaccinated.
Examples of inadequate primary defenses
- Broken skin or mucosa
- traumatized tissue
- decreased ciliary action
- obstructed urine outflow
- altered peristalsis
- change in pH of secretions
- decreased mobility
Examples of inadequate secondary defenses
Reduced hemoglobin level
- suppressed white blood cells (from medication or disease)
- suppressed inflammatory response (from medication or disease)
- low white blood cell count (leukopenia)
Defenses against infection in young/middle-aged adults
- Normal flora
- body system defenses
- inflammation
- immune response - viruses are the most common infectious cause
Changes in defenses with aging
- Declining immune response (especially cell-mediated immunity)
- alterations in skin/urinary tract/lung structure
- function increasing pathogen invasion risk
How does inadequate protein intake affect infection risk?
- Protein breakdown exceeds synthesis
- reducing defenses and impairing wound healing
Nursing assessment for nutritional risk
- Assess dietary intake
- ability to tolerate solid foods
- swallowing/digestive issues
- confusion/weakness affecting self-feeding
How does stress affect infection risk during the alarm stage?
The basal metabolic rate increases as the body uses energy stores. Adrenocorticotropic hormone raises serum glucose and decreases anti-inflammatory responses through cortisone release.
How does prolonged/intense stress impact infection risk?
Elevated cortisone levels result in decreased resistance to infection. Continued stress leads to exhaustion, depleting energy stores and leaving no resistance to invading organisms.
What conditions increase physiological stress and infection risk?
Conditions that increase nutritional requirements like surgery or trauma also increase physiological stress and infection risk.
How do chronic diseases increase infection risk?
Chronic diseases increase infection risk by impairing the immune system’s defenses against infectious organisms.
What diseases/conditions compromise the immune system’s defenses?
Leukemia, AIDS, lymphoma, aplastic anemia weaken defenses against infectious organisms by impacting white blood cell production.
How do other chronic conditions increase infection susceptibility?
Conditions like CAD, diabetes, arthritis, MS cause general debilitation and nutritional impairment increasing infection risk. Cancer, renal failure, vascular disease, and COPD also impair immune defenses.
How do burns increase infection risk?
Burns cause exceedingly high infection susceptibility due to skin damage. Greater burn depth and extent further increases infection risk.
What medications increase infection risk by impairing inflammatory response?
Adrenal corticosteroids are anti-inflammatory medications that cause protein breakdown and impair the inflammatory response against bacteria and pathogens.
How do cytotoxic/antineoplastic medications increase infection susceptibility?
They depress bone marrow activity and cause normal cell toxicity, preventing production of lymphocytes and sufficient white blood cells to fight infection.
What medications taken by transplant recipients increase infection risk?
Cyclosporine and other immunosuppressants decrease the body’s immune response to prevent organ rejection, but also increase susceptibility to infection.
How does radiotherapy for cancer increase infection risk?
Massive radiation doses that destroy cancer cells can also depress bone marrow activity and destroy normal cells needed to fight infection.
What are common sites of localized infections?
Areas of skin or mucous membrane breakdown like wounds, pressure injuries, mouth lesions, and abscesses beneath the skin.
What are the risk factors for infections?
- Inadequate primary and secondary defences
- Nutritional Status
- Stress
- Disease process
- Medical therapy
What are examples of inadequate primary defenses that increase infection risk?
Broken skin or mucosa, traumatized tissue, decreased ciliary action, obstructed urine outflow, altered peristalsis, change in pH of secretions, decreased mobility.
What are examples of inadequate secondary defenses that increase infection risk?
Reduced hemoglobin level, suppression of white blood cells (medication or disease related), suppressed inflammatory response (medication or disease related), low white blood cell count (leukopenia).
How do defenses against infection change with aging?
The immune response, particularly cell-mediated immunity, declines. Older adults also experience alterations in skin, urinary tract, and lung structure/function that increase infection risk.
How does inadequate protein intake affect infection risk?
When protein intake is inadequate, the rate of protein breakdown exceeds tissue synthesis, reducing the body’s defenses against infection and impairing wound healing.
What patient factors increase risk of inadequate dietary intake?
Difficulty swallowing, alterations in digestion, confusion or weakness preventing self-feeding put patients at risk of inadequate intake and subsequent infection risk.
How does stress affect the body’s resistance to infection?
During the alarm stage of stress, cortisone levels increase, leading to decreased resistance to infection. Continued intense stress depletes energy stores, leaving the body with no resistance against invading organisms.
What conditions increase physiological stress and infection risk?
Conditions that increase nutritional requirements like surgery or trauma also increase physiological stress and susceptibility to infections.
How do diseases of the immune system raise infection risk?
Conditions like leukemia, AIDS, lymphoma and aplastic anemia weaken the body’s defenses against infectious organisms by compromising immune function.
What chronic diseases increase susceptibility to infections?
Chronic diseases like coronary artery disease, diabetes, arthritis, multiple sclerosis, cancer, end-stage renal disease, peripheral vascular disease, COPD raise infection risk due to factors like debilitation, nutritional impairment, and impaired immune/body system defenses.
Why do burn patients have an extremely high infection risk?
Burn patients have exceedingly high susceptibility to infection due to the damage to skin surfaces acting as an entry point for pathogens. Greater burn depth and extent further increases this risk.
What medications impair the inflammatory response and increase infection risk?
Adrenal corticosteroids cause protein breakdown and impair the inflammatory response against bacteria and pathogens.
How do cytotoxic/antineoplastic medications raise infection susceptibility?
They depress bone marrow activity, preventing production of lymphocytes and white blood cells needed to fight infection. They also damage normal cells, impairing cellular defenses.
What medications taken by transplant recipients increase infection risk?
Immunosuppressants like cyclosporine decrease the body’s immune response to prevent organ rejection, but also raise susceptibility to infections.
Why are cancer patients receiving radiotherapy at risk for infections?
The high doses of radiation destroy cancerous cells but can also depress bone marrow activity and damage normal cells needed for immune function.
Where are localized infections most common?
Areas of skin or mucosal breakdown like wounds, pressure injuries, mouth lesions, and skin abscesses.
List some chronic diseases that increase infection risk.
Coronary artery disease, cancer, COPD, diabetes mellitus, cardiovascular disease, arthritis, neurodegenerative diseases, renal failure, asthma, comorbidities (having two or more chronic conditions).
What factors related to chronic diseases raise the risk of infection?
Smoking/alcohol use, poor nutrition, obesity, older age, low economic status, unhealthy environment, inactivity, impaired circulation, immunosuppressive medications, compromised host defenses (low WBC count), compromised immune system, stress.
What factors increase the risk of hospital-acquired infections in chronic disease patients?
Long hospitalizations, surgical procedures, invasive procedures like intubation/lines, antibiotic use, wounds/incisions/burns/ulcers, inadequate hand hygiene, exposure to healthcare environment, immobility, treatments like dialysis or TPN.
What should the nurse do first when assessing for localized infection?
Inspect the area for redness and swelling caused by inflammation. Wear disposable gloves if drainage is present.
What may the characteristics of infected drainage indicate?
The color (yellow, green, brown) may suggest the type of pathogen causing the infection.
What symptoms may a patient report with a localized infection?
Pain, tenderness, tightness and edema around the site. Movement may be restricted if the infected area is large.
What are common symptoms of systemic infections?
Fever, fatigue, malaise, enlarged/swollen/tender lymph nodes, loss of appetite, nausea, vomiting.
What should nurses monitor for systemic infection development?
Changes in activity level, lethargy, loss of energy, elevated temperature, increased heart/respiratory rates, low blood pressure, system-specific signs like productive cough or cloudy urine.
Why may infections lack typical signs in older adults?
Lower body temperatures, decreased pain sensation, weaker immune response.
What may be the only symptoms of infection in older adults?
Atypical symptoms like new/increased confusion, incontinence, agitation.
hat percentage of older adults with pneumonia may lack typical symptoms?
Up to 20% may not have fever, chills, or productive cough.
What atypical symptoms may indicate pneumonia in older adults?
Increased heart rate with no reason, confusion, generalized fatigue.
What is important to note about laboratory values for detecting infection?
Laboratory values alone are not sufficient to detect infection. Other clinical signs must also be assessed.
What factors other than infection can alter test values?
Trauma and physical stress can cause an elevation in neutrophil count. Cultures may show organism growth without overt infection signs.
What should nurses assess for patients with infections?
Assess how the infection affects the patient’s and family’s physical, psychological, social and economic needs.