Infection - Antimicrobial Chemotherapy

Question 1

Causative bacteria for pneumonia

Answer 1

• streptococcus pneumonia
• haemophilus influenzae
• staphylococcus aureus
• klebsiella pneumonia

Question 2

Bacteriocidal antibiotics premise

Answer 2

Beta-lactams
Act on cell wall
Kill organisms

Question 3

Indications for bacteriocidal antibiotics

Answer 3

Neutropenia
Meningitis
Endocarditis

Question 4

Bacteriostatic antibiotic premise

Answer 4

Macrolides
Inhibit protein synthesis
Prevent colony growth
Require immune system to “mop up” residual infection

Question 5

Indications for bacteriostatic antibiotics

Answer 5

Toxin-mediated illness

Question 6

Which antibiotics are prone to causing thrush as a side effect

Answer 6

Broad spectrum penicillins and cephalosporins

Question 7

Side effects of gentamycin and vancomycin

Answer 7

Renal side effects (more if pre-existing renal disease)
Ototoxicity
…

Question 8

Which antibiotics inhibit cell synthesis

Answer 8

Beta-lactams: penicillins and cephalosporins

Glycopeptides: vancomycin and teicoplanin

Question 9

Which antibiotics of protein synthesis

Answer 9

Aminoglycosides: gentamycin
Macrolides: clarithromycin
Tetracyclines: doxycyline
Oxazolidonones: linezolid

Question 10

Inhibition of nucleic acid synthesis

Answer 10

Trimethoprim
Sulphonamides: sulphamethoxazole
Quinolones: ciprofloxacin

Question 11

Causative organism for soft tissue infection

Answer 11

• streptococcus pyogenes
• staphylococcus aureus
• streptococcus group C and G

E.coli, pseudomonas aerginosa, clostridium species