Infection - Antibiotics Flashcards
Which medication can be IV or IM?
Gentamicin
Which Drug action is not:
Interfere with bacterial cell-wall synthesis
penicillin with b-lactamase (zosyn)
What is photosensitivity?
sunburn easily
What is the action of piperacillin?
PCN antibiotic that inhibits cell wall synthesis
Which is not a side effect for Penicillin V?
- coagulation abnormalities with high doses
- cross reaction with cephalosporin allergy
- Nephrotoxicity in pts with renal disease
- do not give with grapefruit or citric acids
Nephrotoxicity in pts with renal disease
Reason: Side for Penicillin with B-Lactamase Inhibitor
Which medication has this blackbox:
serious adverse reactions include: tendonitis, tendon rupture, peripheral nephropathy, CNS effects, flare muscle weakness in pts with myasthenia gravis
fluoroquinolones / levofloxacin
Which medication has following black box?
Nephrotoxicity, neurotoxic, ototoxicity, fetal harm
Aminoglycosides / gentamicin
Which medication has side effect:
Disulfiram
Cephalosporins
What is the action of tazobactam?
B-Lactalase Inhibitor that inactivates bacterial beta lactamase
Therapeutic For Penicillin v
Bactericidial
What is gentamicin side effect?
Nephrotoxicity
Ototoxicity
Neurotoxicity
What do each of Gentamicin BB mean?
high risk with impaired renal function and who get higher dosage of prolonged therapy
What is Ototoxicity?
irreversible
What is Neurotoxocity?
numbness, tingling, twitching, convulsions
what is the monitor for Gentamicin?
check pregnancy, hx renal/auditory issues, assess toxicity
monitor for b lactase inhibitor
allergies to PNC drugs, ceph. b lactase inhibitors, nephrotoxicity in pt with renal disease
Do for B lactase Anticipate age related dosage
anticipate age related dosage adjustment in elderly with renal impairment
Do for gentamicin
give plenty fluids, need for peak and trough blood lils to titrate dose
B lactase teach
report s/s thrush, vaginal yeast infections, c. diff, fever that’s not improved below 100 in 3 days, value of eating yogurt/ other products with life culture or taking probiotics
teach for gentamicin
report tendon pain, peripheral neuropathy, jaundice, rash, call provider if possible pregnancy, report tinnitus/ hearing changes and numbness/tingling
