Infection and Response Flashcards

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1
Q

Describe bacteria

A
  • once inside the human body, reproduces very rapidly
  • can release harmful chemicals called toxins
  • toxins damage tissues and make us feel ill
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2
Q

Describe viruses

A
  • cannot reproduce by themselves
  • can only reproduce inside a host cell
  • very damaging to the cell
  • when the virus leaves the cell, it can cause the cell to burst open and die
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3
Q

How are pathogens spread

A
  • air e.g. water droplets sneezing and coughing
  • directly through water like cholera
  • direct contact between individuals
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4
Q

How to prevent spread?

A
  • clean drinking water
  • washing hands
  • condom during intercouse
  • vaccination
  • isolation
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5
Q

Symptoms, spread, effects and prevention of measles

A

symptoms

  • fever
  • a red skin rash 3 days after

spread by:
-droplets when an infected person sneezes or coughs

effects:
-can cause damage to the brain and breathing system

prevention:
-children should be vaccinated very young

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6
Q

Symptoms, treatment, transmission and prevention of HIV

A

symptoms:

  • flu like illness which usually disappears after 1-2 weeks
  • virus attacks the rest fo the immune system, damaging it over time severely
  • patient becomes unable to fight off other infections and cancer cells
  • this is called AIDS

Treatment:

  • antiretroviral drugs stop the virus from multiplying in the patient so it doesn’t damage the immune system
  • they will not develop AIDS and are able to live a normal life

Transmission:

  • exchange of bodily fluids between humans
  • sharing infected needles
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7
Q

Symptoms, transmission and prevention of salmonella.

A

symptoms:

  • fever
  • abdominal cramps
  • vomitting
  • diarrhoea

transmission:

  • eating infected food that is prepared in unhygenic conditions
  • bacteria secrete toxins that cause the symptoms

prevention:

  • cook meat thoroughly
  • vaccinate chickens
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8
Q

Gonorrhoea symptoms, prevention and treatment

A

symptoms:
thick green/yellow discharge from the penis or vagina
pain when urinating

treatment:

  • antibiotics (penicillin)
  • however antibiotic resistant strains are now common

prevention:

  • use condoms
  • get tested if you have unprotected sex
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9
Q

What is a protist?

A
  • single celled eukaryotes

- often transferred to an organism by a vector

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10
Q

Symptoms and preventing malaria

How is malaria spread?

A

symptoms:
-repeated bolts of fever

prevention:

  • stop them breeding by draining areas with still water
  • spray areas of still water with insecticide
  • sleep under a mosquito net sprayed with insecticide

how is it spread?

  1. infected person is bitten by a mosquito
  2. the malaria pathogen passes into the mosquito
  3. now it bites into another person and passes it into them
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11
Q

How does the skin prevent pathogens from entering the body?

A
  • forms protective layer covering the body
  • outer layer consists of dead cells and is difficult for pathogens to penetrate
  • prodeces sebum which kills bacteria
  • when it is damaged, it scabs over to prevent pathogens from entering
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12
Q

How does the nose prevent pathogens from entering the body?

A

-contains hair and mucus which traps pathogens before they enter the breathing system

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13
Q

How do the lungs prevent pathogens from entering the body?

A
  • trachea and the bronchi are covered with tiny hairs called cilia
  • cilia is covered in mucus which traps pathogens
  • now wafts the mucus upwards towards the throat where it is swallowed into the stomach
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14
Q

How does the stomach prevent pathogens from attacking the body?

A
  • contains hydrochloric acid

- kills pathogens before the go further into the digestive system

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15
Q

What does the immune system do?

A

Destroys pathogens and any pathogens they produce.

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16
Q

Explain phagocytosis

A
  • WBC detects chemicals released from the pathogen and moves towards it
  • WBC then ingests the pathogens
  • the WBC uses enzymes to destroy the pathogens
17
Q

What are antibodies and how do they work?

A
  • protein molecules produced by the WBCs
  • the antibodies stick to the pathogens
  • triggers the pathogens to be destroyed
  • extremely specific
  • will not protect you against any other pathogen
  • remain in the blood for a very long time
18
Q

How do antitoxins work?

A
  • WBCs produce these

- they stick to toxin molecules and prevent them from damaging cells

19
Q

How does a vaccination work?

A
  • introduce small quantities of a dead/weakened pathogen into the body
  • won’t lead to disease
  • WBCs are now stimulated to produce antibodies against it
  • WBC divides by mitosis to produce lots of copies of itself
  • they can stay in the blood for decades
  • if the same pathogen enters, the WBCs can produce antibodies quickly, preventing infection
20
Q

What is herd immunity?

A
  • important that many people get vaccinated
  • if enough people are, it protects unvaccinated people
  • there won’t be anyone around the unvaccinated person that can pass the pathogen on
21
Q

Why is it difficult to develop drugs that kill viruses?

A
  • viruses live and reproduce inside human cells

- so the drugs could damage the body’s cells and tissues

22
Q

What do lymphocytes produce antibodies against?

A

Antigens

23
Q

explain the monoclonal anitbody mouse thing

A
  • inject a mouse with antigen
  • lymphocytes will produce antibodies against it
  • collect the lymphocytes from the mouse
  • fuse the lymphoyctes with the tumour cell
  • tumour cells are very good at dividing by mitosis
  • hybridoma cell produced
  • these can produce antibodies and divide by mitosis
  • select a single hybridoma producing the antibody we want
  • hybridoma divides by mitosis to form a clone of identical cells
  • antibodies produced are all identical
24
Q

How are monoclonal antibodies used in pregnancy testing?

A
  • detect a specific hormone
  • which is produced by the placenta of the developing fetus
  • cheap and easy to use
  • simply urinate and look for a reaction
  • highly accurate
25
Q

How are monoclonal antibodies used in lab testing?

A
  • measure the level of hormones in blood
  • we can use them to detect pathpgens in the blood
  • completely specific to what they are looking for
26
Q

How do monoclonal antibodies work?

A

They are produced from a single clone of identical hybridoma cells.
Monoclonal antibodies are specific to a single binding site on one protein antigen.
We can produced monoclonal antibodies against any antigen we want.

27
Q

How are monoclonal antibodies used to locate specific molecules in a cell or tissue?

A

The monoclonal antibodies are attached to fluorescent dyes.

The antibodies then stick to specific molecules within the cell and allow us to see their locations.

27
Q

How are monoclonal antibodies used to locate specific molecules in a cell or tissue?

A

The monoclonal antibodies are attached to fluorescent dyes.

The antibodies then stick to specific molecules within the cell and allow us to see their locations.

28
Q

How do monoclonal antibodies prevent cancer growth?

A
  • antibodies can be made specific to the cancer cells
  • they attach a radioactive substance of a toxic drug to the antibody
  • when injected into the blood , it attaches to cancer cells
  • the substance/toxic drug stops the cancer cells from growing and dividing