Infection and Immunity :Perioperative prophylaxis Flashcards

1
Q

What is prophylaxis?

A

treatment given, or action taken to prevent disease

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1
Q

What are Healthcare Associated Infections?

A
  • MRSA
    • From poor hygiene, indwelling catheters
  • Clostridium difficile
    • Antibiotics, proton pump inhibitors, poor hygiene
  • Extended Spectrum Beta-Lactamase (ESBL)
    • Urinary catheters
  • Surgical site infections
    • Infections from gram negative bacteria, MRSA, group A streptococcus, anaerobes
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2
Q

What are the main ways that infection if prevented?

A
  • Infection control in healthcare
  • Vaccines
  • Post-exposure prophylaxis
  • Outbreak investigation → find out how far outbreak has spead, how is involved, how it can be contained?
  • Standardisation
  • Aseptic Non Touch Technique (ANTT) → used in clinical procedures
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3
Q

Why do we need to prevent infection?

A

need to prevent infection: to reduce morbidity and mortality, which may result from sepsis

reduce length of stay in hospital and risk of hospital procedures

less economic burden

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4
Q

What are the Principles of Prevention?

A
  • Remove sources
  • Block routes of transfer
  • Enhanced natural resistance
  • Offer chemical (antimicrobial) prophylaxis
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5
Q

What are the routes of transmission?

A
  • airdrops
    -direct contact
    -faecal-oral
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6
Q

How to prevent airborne transmission?

A
  • Place patients in source isolation
  • Use filtered air, negative pressure
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7
Q

How to prevent Direct contact?

A
  • patients placed in source isolation → esp with microorganisms that easily spread
  • Aseptic technique, hand hygiene
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8
Q

How to Minimise and Control Exposure to Microorganisms

A
  • Decontamination of contaminated equipment
  • Uncontaminated food and drinks to pts.
  • Safe disposal of hospital waste
  • Screening (pts.) and immunisation (staff)
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9
Q

What are the factors that affect infection?

A
  • Microorganisms
  • host
  • enviroment
  • treatment: previous and current
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