infection

Question 1

immunocompromised abx selection

Answer 1

bacteriocidal > bacteriostatic

Question 2

prophylactic vs therapeutic vs empiric abx

Answer 2

prophylactic - preventative (surgery, immunocompromised, freq infx)

therapeutic - you know the pathogen

empiric - unknown but common pathogen, immunocompromised

Question 3

when to start empiric abx

Answer 3

hemodynamic instabillity or immunocompromised

do NOT start for unknown source of fever

Question 4

what do beta lactase not treat and why

Answer 4

atypical bacteria

because they do not have a cell wall

Question 5

main causes of C. Diff

Answer 5

clindamycin, fluoroquinolone, 2/3rd gen cephalosporins

Question 6

cell wall synthesis inhibitors

Answer 6

bactericidal

penicillins
cephalosporins
carbapenems
monobactam (azotrenam)
glycopeptides (vancomycin)

Question 7

protein synthesis inhibtors

Answer 7

bacteriostatic

macrolides
tetracyclines
lincomycin (clindamycin)

Question 8

common BC contaminants

Answer 8

coagulase negative staph
corynebacterium spp.
bacillus spp.
propionibacterium acnes
micrococcus

Question 9

anti fungal AEs

Answer 9

nausea
vomiting
hypoK
elevated LFTs