Infec Flashcards
What bacteria commonly cause bacterial conjunctivitis?
Staphylococcus aureus
Streptococcus pneumoniae
Haemophilus influenzae
1st line for bacterial conjunctivitis?
Chloramphenicol
What is chloramphenicol contraindicated in?
Porphyria
What antibiotic can cause cholestatic jaundice
Flucloxacillin
What class of antibiotics are nephrotoxic and ototoxic
Aminoglycosides
What common side effect do all antibiotics cause
Diarrhoea
What is the normal dose of Piperacillin with Tazosin and the pseudomonas cover dose
4.5g q8h
4.5g QDS
Which antibiotics need TDM
Gentamicin, Vancomycin, Teicoplanin, Amikacin
H. Pylori eradication
7 day course
Amoxicillin 1g BD + Clarithromycin 500mg BD + Omeprazole 40mg OD
Penicillin allergic
Clarithromycin + Metronidazole 400mg TDS + PPI
What is co-administered with Isoniazid and why
Pyridoxine to reduce peripheral neuropathy effects
Which antimalarial if a patient has rheumatoid arthritis
Chloroquine
Which Abx can cause fatal arrhythmias with Amiodarone and how
Clarithromycin, Erythromycin CYP3A4 inhibitors
Ciprofloxacin can prolong QT which would warrant monitoring
How does renal function affect Nitrofurantoin
CI <45mL/min
Wont work as it can’t get through kidney into urine
When are prophylactic antibiotics indicated
2 infections within 6 months
Risks of long term antibiotic prophylaxis
Liver
Pulmonary fibrosis
Peripheral neuropathy
Risks of long term antibiotic prophylaxis
Liver
Pulmonary fibrosis
Peripheral neuropathy
A patient with a sore throat has been taking amoxicillin for tonsillitis and develops a rash, they’ve not had a rash from penicillins before, what action
Glandular fever and penicillins causes a rash, refer to GP as it isn’t an allergic reaction rash
How long after stopping isotretinoin can you give blood
4 weeks
How long should UTIs be treated for in different populations
F 3d
Preg F 7d
M 7d
CAUTI 5-7d
OTC advice to Doxycycline course
Photosensitive
Headache common will subside
Avoid <12
Pregnant UTI 1st line
Cefalexin
Catheter associated UTI drug
Pivmecillinam
Vancomycin issues
Nephrotoxic
Ototoxic
SJS
Red man syndrome
Clostridium difficile treatment pathway
1st Vancomycin PO
2nd Fidaxomycin
Relapse <12w Fidaxomycin
Relapse >12w Vancomycin
ALT Metronidazole
Suspend all laxatives, PPIs and Antacids
Drugs that cause C.diff
Clindamycin
Cefalosporins
Co-Amoxiclav
Ciprofloxacin
PPIs
Dog bite ABX
Co-Amoxiclav
Outline the CURB65 scoring system
1 Confusion
1 Urea >7
1 RR >=30
1 BP SYS <90 / DIA =<60
1 Age >=65
Outline the FeverPAIN scoring system
1 Fever in last 24h
1 No cough or coryza (runny congested nose)
1 Symptom onset =<3d
1 Purulent tonsils
1 SEV tonsil inflammation
