Infec

Question 1

What bacteria commonly cause bacterial conjunctivitis?

Answer 1

Staphylococcus aureus
Streptococcus pneumoniae
Haemophilus influenzae

Question 2

1st line for bacterial conjunctivitis?

Answer 2

Chloramphenicol

Question 3

What is chloramphenicol contraindicated in?

Answer 3

Porphyria

Question 4

What antibiotic can cause cholestatic jaundice

Answer 4

Flucloxacillin

Question 5

What class of antibiotics are nephrotoxic and ototoxic

Answer 5

Aminoglycosides

Question 6

What common side effect do all antibiotics cause

Answer 6

Diarrhoea

Question 7

What is the normal dose of Piperacillin with Tazosin and the pseudomonas cover dose

Answer 7

4.5g q8h
4.5g QDS

Question 8

Which antibiotics need TDM

Answer 8

Gentamicin, Vancomycin, Teicoplanin, Amikacin

Question 9

H. Pylori eradication

Answer 9

7 day course
Amoxicillin 1g BD + Clarithromycin 500mg BD + Omeprazole 40mg OD

Penicillin allergic
Clarithromycin + Metronidazole 400mg TDS + PPI

Question 10

What is co-administered with Isoniazid and why

Answer 10

Pyridoxine to reduce peripheral neuropathy effects

Question 11

Which antimalarial if a patient has rheumatoid arthritis

Answer 11

Chloroquine

Question 12

Which Abx can cause fatal arrhythmias with Amiodarone and how

Answer 12

Clarithromycin, Erythromycin CYP3A4 inhibitors

Ciprofloxacin can prolong QT which would warrant monitoring

Question 13

How does renal function affect Nitrofurantoin

Answer 13

CI <45mL/min
Wont work as it can’t get through kidney into urine

Question 14

When are prophylactic antibiotics indicated

Answer 14

2 infections within 6 months

Question 15

Risks of long term antibiotic prophylaxis

Answer 15

Liver
Pulmonary fibrosis
Peripheral neuropathy

Question 16

Risks of long term antibiotic prophylaxis

Answer 16

Liver
Pulmonary fibrosis
Peripheral neuropathy

Question 17

A patient with a sore throat has been taking amoxicillin for tonsillitis and develops a rash, they’ve not had a rash from penicillins before, what action

Answer 17

Glandular fever and penicillins causes a rash, refer to GP as it isn’t an allergic reaction rash

Question 18

How long after stopping isotretinoin can you give blood

Answer 18

4 weeks

Question 19

How long should UTIs be treated for in different populations

Answer 19

F 3d
Preg F 7d
M 7d
CAUTI 5-7d

Question 20

OTC advice to Doxycycline course

Answer 20

Photosensitive
Headache common will subside
Avoid <12

Question 21

Pregnant UTI 1st line

Answer 21

Cefalexin

Question 22

Catheter associated UTI drug

Answer 22

Pivmecillinam

Question 23

Vancomycin issues

Answer 23

Nephrotoxic
Ototoxic
SJS
Red man syndrome

Question 24

Clostridium difficile treatment pathway

Answer 24

1st Vancomycin PO
2nd Fidaxomycin
Relapse <12w Fidaxomycin
Relapse >12w Vancomycin
ALT Metronidazole
Suspend all laxatives, PPIs and Antacids

Question 25

Drugs that cause C.diff

Answer 25

Clindamycin
Cefalosporins
Co-Amoxiclav
Ciprofloxacin
PPIs

Question 26

Dog bite ABX

Answer 26

Co-Amoxiclav

Question 27

Outline the CURB65 scoring system

Answer 27

1 Confusion
1 Urea >7
1 RR >=30
1 BP SYS <90 / DIA =<60
1 Age >=65

Question 28

Outline the FeverPAIN scoring system

Answer 28

1 Fever in last 24h
1 No cough or coryza (runny congested nose)
1 Symptom onset =<3d

1 Purulent tonsils
1 SEV tonsil inflammation