Inf Dz's of the Dog pt 2

Question 1

Clinical signs of C botulinum

Answer 1

• weakness and flacid paralysis
• progressive, symmetrical ascending paralysis
• mydriasis, decreased gag reflex, excess salication, diminished palpebral reflexes and weak vocalization
• HR variable, constipation/urinary retention might happen

Question 2

Dx of C botulinum

Answer 2

CS
EMG
Finding the toxin in serum, feces, vomitus, or stomach content

Question 3

Tx for C botulinum

Answer 3

supportive care
anti toxin is Crap bc it’s doesn’t contain specific type C (for crap) antitoxin
Antibacterials- metro or penicillin
prev- heat food + vx

Question 4

2 toxins found in C tetani

Answer 4

tetanoleptin- hemolysis of rbcs

tetanospasmin- neuro dysfunction

Question 5

Clinical findings of C tetani

Answer 5

sardonic grin
trismus (lock jaw)
salivation, dysphagia, rigid gait
progresses to opisthotonus, convulsions, and resp comprimise -> death

Question 6

Dx of C tetani

Answer 6

CS
leukocytosis and LS neutrophilia 
tachy/bradyarrythmia 
megaesophagus on rads 
isolation of bacterium from wound (not likely)

Question 7

Tx for C tetani

Answer 7

toxin wears off in 3-4 wks, supportive care til then
antitoxin IM (careful of allergic rxns)
Antibiotics (metro, pen G, tetra)
Sedatives, muscle relaxants, antimuscarinics, sx and wound mgt, nursing care

Question 8

What transmits Mycoplasma haemocanis

Answer 8

brown tick rhiphicephalus sanguineus

Question 9

What is required before CS develop for M haemocanis

Answer 9

splenectomy

Question 10

Dx of M haemocanis?

Answer 10

PCR or seeing organism on blood smear

Question 11

Tx of M haemocanis?

Answer 11

Doxycyline

Question 12

Dx of Bartonellosis

Answer 12

Serology (only 50%, no good) 
BacT isolation (PCR)

Question 13

Tx of Bartonellosis

Answer 13

Doxycycline

Question 14

Rocky mountain spotted fever

Answer 14

rickettsia rickettsia

Question 15

monocytotrophic ehrlichiosis

Answer 15

e canis, e chaffeensis

Question 16

granulocytotrophic ehrlichiosis

Answer 16

e ewingii

Question 17

granulocytotrophic anaplasmosis

Answer 17

anaplasma phagocytophilum

Question 18

thrombocytoropic anaplasmosis

Answer 18

a platys

Question 19

salmon poisoning

Answer 19

neorickettsia helminthoeca

Question 20

Pathophysiology for Rickettsial Dzs

Answer 20

Rickettsia enters the blood, replicates in endothlial cells -> vascular damage and increase in vascular permeability and leakage of fluids/rbcs into extravascular space
vasculitis leads to decreased platelets and decreased albumin

Question 21

Vector for e canis or e chaffeensis

Answer 21

rhiphichepalis spp

Question 22

A equi or A ewingii, cells infected and CS

Answer 22

infected neutrophils

lameness, fever, joint swelling, pain

Question 23

Vector for A phagocytophilum

Answer 23

ioxdes

Question 24

A platys cells infected and CS

Answer 24

platelets

usually non clinical but can see cyclic rickettsemia and thrombocytopenia

Question 25

Dx of Rickettsial Dz’s

Answer 25

cytology
serology
PCR

Question 26

Chronic Rickettsial Dz is mainly due to

Answer 26

E canis

Question 27

MDB for Rickettsial dz’s

Answer 27

thrombocytopenia
neutropenia w/ lymphocytosis 
anemia
hypoalb, hyperglob
proteinuria

Question 28

Salmon poisoing, where can you find it, CS, DX, Rx

Answer 28

WA, OR, CA
Fever, v/d, weight loss, lymphadenopathy, splenomegaly
Dx: fecal= fluke eggs, FNA of LN= rickettsial inclusions
Rx: supportive care + tetra/doxy