Industrial Dust Diseases Flashcards

1
Q

what is coal workers pneumoconiosis

A

due to inhalation coal dust particles over 15-20y. ingested by macrophages which die and release enzymes leading to fibrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is coal workers pneumoconiosis

A

due to inhalation coal dust particles over 15-20y. ingested by macrophages which die and release enzymes leading to fibrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

features coal workers pneumoconiosis

A

mainly asymptomatic. co existing chronic bronchitis.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

CXR coal workers pneumoconiosis

A

many round opacities (upper zone)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what can CWP lead to due to progression

A

progressive massive fibrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

signs progressive massive fibrosis

A

progressive dyspnoea, fibrosis, cor pulmonale

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

CXR PWF

A

upper zone fibrotic masses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

caplans

A

RA, pneumoconiosis, pulmonary rheum nodules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what is silicosis

A

silica is fibrogenic. jobs- sand blasting, stone quarrying

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

features silicosis

A

progressive dyspnoea, incr TB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

CXR silicosis

A

diffuse military or nodular pattern, egg shell calcification hilar nodes.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what is the most fibrogenic particle in asbestosis

A

crocidolite (blue)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

which is the least fibrogenic particle in asbestosis

A

chrysolite (white)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

features asbestosis

A

progressive dyspnoea, clubbing, fine end crackles, incr risk adenocarcinoma and mesothelioma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is malignant mesothelioma

A

tumour of mesothelial cells in the pleura. occupational exposure to asbestos

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

features malignant mesothelioma

A

chest pain, dyspnoea, weight loss, clubbing, recurrent effusion, met disease signs- lymphadenopathy, hepatomegaly, bone pain/tenderness, abdo pain/obstruction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

tests MM

A

CXR/CT, bloody pleural fluid

18
Q

diagnosis MM

A

histology, autopsy

19
Q

management MM

A

pemetrexed + cisplatin. surgery. pleurodesis

20
Q

what is pleurodesis

A

artificially obliterating the pleural space

21
Q

prognosis MM

A
22
Q

features coal workers pneumoconiosis

A

mainly asymptomatic. co existing chronic bronchitis.

23
Q

CXR coal workers pneumoconiosis

A

many round opacities (upper zone)

24
Q

what can CWP lead to due to progression

A

progressive massive fibrosis

25
Q

signs progressive massive fibrosis

A

progressive dyspnoea, fibrosis, cor pulmonale

26
Q

CXR PWF

A

upper zone fibrotic masses

27
Q

caplans

A

RA, pneumoconiosis, pulmonary rheum nodules

28
Q

what is silicosis

A

silica is fibrogenic. jobs- sand blasting, stone quarrying

29
Q

features silicosis

A

progressive dyspnoea, incr TB

30
Q

CXR silicosis

A

diffuse military or nodular pattern, egg shell calcification hilar nodes.

31
Q

what is the most fibrogenic particle in asbestosis

A

crocidolite (blue)

32
Q

which is the least fibrogenic particle in asbestosis

A

chrysolite (white)

33
Q

features asbestosis

A

progressive dyspnoea, clubbing, fine end crackles, incr risk adenocarcinoma and mesothelioma

34
Q

what is malignant mesothelioma

A

tumour of mesothelial cells in the pleura. occupational exposure to asbestos

35
Q

features malignant mesothelioma

A

chest pain, dyspnoea, weight loss, clubbing, recurrent effusion, met disease signs- lymphadenopathy, hepatomegaly, bone pain/tenderness, abdo pain/obstruction

36
Q

tests MM

A

CXR/CT, bloody pleural fluid

37
Q

diagnosis MM

A

histology, autopsy

38
Q

management MM

A

pemetrexed + cisplatin. surgery. pleurodesis

39
Q

what is pleurodesis

A

artificially obliterating the pleural space

40
Q

prognosis MM

A