Industrial Dust Diseases Flashcards
what is coal workers pneumoconiosis
due to inhalation coal dust particles over 15-20y. ingested by macrophages which die and release enzymes leading to fibrosis
what is coal workers pneumoconiosis
due to inhalation coal dust particles over 15-20y. ingested by macrophages which die and release enzymes leading to fibrosis
features coal workers pneumoconiosis
mainly asymptomatic. co existing chronic bronchitis.
CXR coal workers pneumoconiosis
many round opacities (upper zone)
what can CWP lead to due to progression
progressive massive fibrosis
signs progressive massive fibrosis
progressive dyspnoea, fibrosis, cor pulmonale
CXR PWF
upper zone fibrotic masses
caplans
RA, pneumoconiosis, pulmonary rheum nodules
what is silicosis
silica is fibrogenic. jobs- sand blasting, stone quarrying
features silicosis
progressive dyspnoea, incr TB
CXR silicosis
diffuse military or nodular pattern, egg shell calcification hilar nodes.
what is the most fibrogenic particle in asbestosis
crocidolite (blue)
which is the least fibrogenic particle in asbestosis
chrysolite (white)
features asbestosis
progressive dyspnoea, clubbing, fine end crackles, incr risk adenocarcinoma and mesothelioma
what is malignant mesothelioma
tumour of mesothelial cells in the pleura. occupational exposure to asbestos
features malignant mesothelioma
chest pain, dyspnoea, weight loss, clubbing, recurrent effusion, met disease signs- lymphadenopathy, hepatomegaly, bone pain/tenderness, abdo pain/obstruction