Induction Agents Flashcards

1
Q

How long should it take for induction agents to work?

What is this the equivalent of?

A

10-20 seconds

1-2 arm-brain circulation times

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2
Q

What is the most common induction agent?

A

Propofol

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3
Q

What are 2 benefits of propofol?

A

Very good airway suppression

Lowers risk of PONV

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4
Q

What effect does propofol have on BP and HR?

A

Lowers both BP and HR

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5
Q

What are 2 cons of propofol?

A

Pain on injection (lipid-based)

Involuntary movements

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6
Q

What is thiopentone mainly used for?

A

Rapid sequence induction

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7
Q

What is a pro of thiopentone over propofol?

A

Faster acting than propofol

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8
Q

What are two benefits of thiopentone?

A

anti-epileptic properties

Protects the brain

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9
Q

What effect does thiopentone have on HR and BP

A

Increases HR, decreases BP

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10
Q

What condition is thiopentone contraindicated in?

A

Porphyria (metabolic disorder where not enough haem is produced)

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11
Q

What are the risks associated with thiopentone?

A

Rash/ bronchospasm

Intra-arterial injection–> thrombosis & gangrene

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12
Q

What is often the sole anaesthetic for short procedures?

A

Ketamine

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13
Q

What effect does ket have on HR and BP?

A

Rise in HR and rise in BP

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14
Q

What is the onset of ketamine?

A

90 seconds

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15
Q

What effect does ket have on the airway?

A

Bronchodilation

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16
Q

Give 2 cons of ketamine

A
N+V
Emergence phenomenon (closely mimics schizophrenia)
17
Q

Give 3 pros of etomidate

A

Rapid onset
Haemodynamic stability (BP stays as it is)
Lowest risk of hypersensitivity

18
Q

Give 4 cons of etomidate

A

Pain on injection
Spontaneous movements
PONV
Adrenal-corticol suppression

19
Q

When is adreno-corticol suppression most dangerous?

A

Post op <72 hours

20
Q

Best induction agent:

changing a burns dressing

A

ketamine

21
Q

Undergoing an op under GA

A

propofol

22
Q

Requires GA, history of heart failure

A

Etomidate (haemdynamic stability)

23
Q

Give 4 induction agents

A

Propofol
Thiopentone
Ketamine
Etomidate