Induction Agents

Question 1

What is the adult induction dose for Propofol?

Answer 1

1.5 - 2.5mg/kg

Question 2

What is the onset of action for Propofol?

Answer 2

Approx. 30-60 seconds.

Question 3

What is the duration of action for Propofol?

Answer 3

5-10 minutes.

Question 4

Does Propofol cause pain on injection?

Answer 4

Yes.

Question 5

Why does Propofol cause a drop in blood pressure?

Answer 5

This is mainly due to systemic vasodilation.

Question 6

What are the effects of Propofol?

Answer 6

1. Vasodilation.
2. Respiratory depression.
3. It has an antiemetic effect.

Question 7

Why do we use Propofol and how does it work?

Answer 7

It is an induction agent.
Propofol suppresses laryngeal reflexes, allowing LMA insertion.

Question 8

How is Propofol administered?

Answer 8

Intravenously.

Question 9

What are the common side effects of Propofol?

Answer 9

1. Apnoea
2. Arrhythmia
3. Headache
4. Hypotension (low BP)
5. Nausea
6. Vomiting
7. Localised pain

Question 10

What is the adult induction dose of Thiopentone?

Answer 10

3-7mg/kg

Question 11

What is the onset of Thiopentone?

Answer 11

20-30 seconds

Question 12

What is the duration of action of Thiopentone?

Answer 12

5-10 minutes

Question 13

Describe the onset of Thiopentone.

Answer 13

A smooth onset with good definitive endpoints.

Question 14

When Thiopentone has been administered, what causes intense pain and tissue necrosis?

Answer 14

Extravasation.

Question 15

When is Thiopentone the drug of choice?

Answer 15

In RSI, seizures & neuro (anticonvulsant).