Indoor Air pollution Flashcards
Most common indoor pollution
Tobacco smoke
Other common indoor pollution
Nitrogen Dioxide, asbestos, Carbon Monoxide
Common indoor pollution sources
Polycyclic aromatic hydrocarbons
comes from cooking oils and burning of coal
Polycyclic aromatic hydrocarbons
Derived from microbiologic agents (pet dander, dust mites, fungi, molds)
Bioaerosols
can cause Legionnaire’s disease
Bioaerosols
comes from uranium and can cause Lung cancer
Radon
in building materials (cabinets, furniture)
Formaldehyde
causes breathing difficulties, burning sensation in the eyes & throat, trigger asthma and a carcinogen
Formaldehyde
What is Sick building Syndrome
exposure to 1 or more indoor pollutants
Irreversible CNS disturbance and peripheral neuropathy
High levels of Lead
Subclinical Lead poisoning in children (level)
<45ug
80-85% absorbed in bone and and teeth, competes with Ca and binds with Phosphates
Lead
found in residential paints and gasoline
Lead
Mild dysfunction, reduced IQ, learning disabilities, delayed psychomotor development, higher intestinal absorption, more permeable to BBB
Chronic Lead exposure in children
Higher doses of what chemical leads to blindness, psychoses, seizure, coma and death
Lead
Interferes with normal remodeling of cartilage and primary bone trabeculae in the epiphyses
Lead lines
Excess pigmentation in the gums caused by
Lead
Inhibits healing of fractures by increasing chondrogenesis and delaying cartilage mineralization
Lead
Type of anemia in Lead poisoning
Microcytic Hypochromic anemia
Enzymes inhibited by Lead
Ferrochelatase and Delta aminolevullinic acid
Inhibition of what pump leads to RBC hemolysis (Lead)
Na-K-ATPase pump
Diagnosis of Lead poisoning:
Neurologic changes + anemia + basophilic stippling in red cells
Diagnosis of Lead poisoning (zinc-bound red-cell level)
> 50ug/dL
