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Patho. > Indoor Air pollution > Flashcards

Indoor Air pollution Flashcards

1
Q

Most common indoor pollution

A

Tobacco smoke

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2
Q

Other common indoor pollution

A

Nitrogen Dioxide, asbestos, Carbon Monoxide

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3
Q

Common indoor pollution sources

A

Polycyclic aromatic hydrocarbons

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4
Q

comes from cooking oils and burning of coal

A

Polycyclic aromatic hydrocarbons

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5
Q

Derived from microbiologic agents (pet dander, dust mites, fungi, molds)

A

Bioaerosols

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6
Q

can cause Legionnaire’s disease

A

Bioaerosols

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7
Q

comes from uranium and can cause Lung cancer

A

Radon

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8
Q

in building materials (cabinets, furniture)

A

Formaldehyde

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9
Q

causes breathing difficulties, burning sensation in the eyes & throat, trigger asthma and a carcinogen

A

Formaldehyde

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10
Q

What is Sick building Syndrome

A

exposure to 1 or more indoor pollutants

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11
Q

Irreversible CNS disturbance and peripheral neuropathy

A

High levels of Lead

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12
Q

Subclinical Lead poisoning in children (level)

A

<45ug

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13
Q

80-85% absorbed in bone and and teeth, competes with Ca and binds with Phosphates

A

Lead

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14
Q

found in residential paints and gasoline

A

Lead

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15
Q

Mild dysfunction, reduced IQ, learning disabilities, delayed psychomotor development, higher intestinal absorption, more permeable to BBB

A

Chronic Lead exposure in children

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16
Q

Higher doses of what chemical leads to blindness, psychoses, seizure, coma and death

A

Lead

17
Q

Interferes with normal remodeling of cartilage and primary bone trabeculae in the epiphyses

A

Lead lines

18
Q

Excess pigmentation in the gums caused by

A

Lead

19
Q

Inhibits healing of fractures by increasing chondrogenesis and delaying cartilage mineralization

A

Lead

20
Q

Type of anemia in Lead poisoning

A

Microcytic Hypochromic anemia

21
Q

Enzymes inhibited by Lead

A

Ferrochelatase and Delta aminolevullinic acid

22
Q

Inhibition of what pump leads to RBC hemolysis (Lead)

A

Na-K-ATPase pump

23
Q

Diagnosis of Lead poisoning:

A

Neurologic changes + anemia + basophilic stippling in red cells

24
Q

Diagnosis of Lead poisoning (zinc-bound red-cell level)

A

> 50ug/dL

25
Q

Diagnosis of Lead poisoning: Zn-_______ levels

A

Zn-protoporphyrin levels

26
Q

Detection of Lead poisoning in mild cases

A

Anemia

27
Q

(3) Morphology of Blood cell in Lead poisoning (LP)

A

ring sideroblast, microcytic hypochromic, baspophilic stippling of RBCs

28
Q

Peripheral demyelinating neuropathy in LP

A

Wrist drop then foot drop

29
Q

assoc. with intranuclear inclusions, interstitial fibrosis and saturnine gout

A

Kidney damage in LP

30
Q

Most severe case (what organ) in LP

A

Brain

Patho. (2 decks)

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